Differential activation and tyrosine hydroxylase distribution in the hippocampal, pallial and midbrain brain regions in response to cognitive performance in Indian house crows exposed to abrupt light environment

Taufique, S. K. Tahajjul; Kumar, Vinod

doi:10.1016/j.bbr.2016.07.046

Cited by 28 publications

(30 citation statements)

References 57 publications

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“…Light at night (LAN, an illuminated night) can blur the boundaries of day and night and affect the synchronization of many circadian clock‐controlled functions, e.g., daily cycles of activity‐rest, sleep‐wake, and melatonin secretion (de Jong et al., ; Gaston, Davies, Nedelec, & Holt, ; Ouyang et al., ). Emerging evidence suggests association of LAN‐induced circadian disruptions with increasing incidences of metabolic dysfunctions, cognition impairment, and mood disorders in both nocturnal and diurnal species (Bedrosian, Weil, & Nelson, ; Fonken, Kitsmiller, Smale, & Nelson, ; Fonken & Nelson, ; Gaston et al., ; Ikeno & Yan, ; Lunn et al., ; Taufique & Kumar, ).…”

Section: Introductionmentioning

confidence: 99%

“…Furthermore, a no‐night light (constant light, LL) environment caused negative effects on daily behavioural patterns, advanced brain functions like the acquisition of learning and cognition, and novel object exploration (NOE) in zebra finches ( Taeniopygia guttata ) when adult, and in the future generation (Jha & Kumar, ). LL also induced circadian rhythm disruptions and caused impairment of visuo‐spatial learning and memory in Indian house crows, Corvus splendens (Taufique & Kumar, ).…”

Section: Introductionmentioning

confidence: 99%

“…At the brain level, the accumulated evidence suggests the role of hippocampus (HP) in learning (Nadel, ; Taufique & Kumar, ), novel object location recognition (Crusio, ; Squire, Stark, & Clark, ), and mood performance (Becker & Wojtowicz, ). LAN negatively affected neural plasticity as shown by decreased spine density, altered dendritic morphology, and suppressed neurogenesis in HP of both nocturnal and diurnal rodents (Bedrosian, Fonken, Walton, Haim, & Nelson, ; Fonken et al., ; Fujioka et al., ).…”

Section: Introductionmentioning

confidence: 99%

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Illuminated night alters hippocampal gene expressions and induces depressive‐like responses in diurnal corvids

Taufique

Prabhat

Kumar

2018

Eur J of Neuroscience

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Artificial light at night induces circadian disruptions and causes cognitive impairment and mood disorders; yet very little is known about the neural and molecular correlates of these effects in diurnal animals. We manipulated the night environment and examined cellular and molecular changes in hippocampus, the brain region involved in cognition and mood, of Indian house crows (Corvus splendens) exposed to 12 hr light (150 lux): 12 hr darkness (0 lux). Diurnal corvids are an ideal model species with cognitive abilities at par with mammals. Dim light (6 lux) at night (dLAN) altered daily activity:rest pattern, reduced sleep, and induced depressive-like responses (decreased eating and self-grooming, self-mutilation, and reduced novel object exploration); return to an absolute dark night reversed these negative effects. dLAN suppressed nocturnal melatonin levels; however, diurnal corticosterone levels were unaffected. Concomitant reduction of immunoreactivity for DCX and BDNF suggested dLAN-induced suppression of hippocampal neurogenesis and compromised neuronal health. dLAN also negatively influenced hippocampal expression of genes associated with depressive-like responses (bdnf, il-1β, tnfr1, nr4a2), but not of those associated with neuronal plasticity (egr1, creb, syngap, syn2, grin2a, grin2b), cellular oxidative stress (gst, sod3, cat1) and neuronal death (caspase2, caspase3, foxo3). Furthermore, we envisaged the role of BDNF and showed epigenetic modification of bdnf gene by decreased histone H3 acetylation and increased hdac4 expression under dLAN. These results demonstrate transcriptional and epigenetic bases of dLAN-induced negative effects in diurnal crows, and provide insights into the risks of exposure to illuminated nights to animals including humans in an urban setting.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Illuminated night alters hippocampal gene expressions and induces depressive‐like responses in diurnal corvids

Taufique

Prabhat

Kumar

2018

Eur J of Neuroscience

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“…A bin of sections containing the hypothalamic region was processed for double‐labelled IHC of CART/NPY, GnRH/GnIH, or ZENK/TH. We used a standard avidin‐biotin peroxidase protocol that has been standardised in our laboratory . Briefly, PBS sections washed three times (pH 7.4) were successively treated with hydrogen peroxide (0.3% dissolved in methanol, 30 minutes) and bovine serum albumin (1% dissolved in PBS containing 0.3% Triton‐X‐100 [PBSBT], 60 minutes) to block endogenous peroxidase activity and non‐specific binding, respectively.…”

Section: Methodsmentioning

confidence: 99%

Changes in brain peptides associated with reproduction and energy homeostasis: Putative roles of gonadotrophin‐releasing hormone‐II and tyrosine hydroxylase in determining reproductive performance in response to daily food availability times in diurnal zebra finches

Mishra

Agarwal

Prabhat

et al. 2020

J Neuroendocrinology

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Previous studies have demonstrated ‘quality‐quantity’ trade‐offs with daily food availability times in zebra finches. Compared with food access ad lib., zebra finch pairs with restricted food access for 4 hours in the morning produced poor quality offspring, whereas those with the same food access in the evening produced fewer but better quality offspring. The present study investigated whether food‐time‐dependent differential effects on reproductive performance involved brain peptides associated with reproduction and energy homeostasis in zebra finches. We measured peptide/protein expression of gonadotrophin‐releasing hormone (GnRH)‐I, GnRH‐II, gonadotrophin‐inhibitory hormone (GnIH), tyrosine hydroxylase (TH), neuropeptide Y (NPY), cocaine‐ and amphetamine regulated transcript (CART) and ZENK (a neuronal activation marker) by immunohistochemistry and mRNA expression of genes coding for the type 2 (DIO2) and type 3 (DIO3) deiodinase by a quantitative polymerase chain reaction in male and female zebra finches that were paired and kept under a 12:12 hour light/dark photocycle at 24 ± 2°C temperature for > 12 months with access to food ad lib., or for only 4 hours in the morning or evening. In both sexes, GnRH‐I, DIO2 and DIO3 expression did not differ significantly between the three feeding conditions, although levels showed an overall food effect. However, in males, GnIH expression was significantly higher in evening‐fed birds compared to ad lib. fed birds. Interestingly, GnRH‐II and TH levels were significantly lower in restricted feeding compared to the ad lib. group and, importantly, GnRH‐II and TH‐immunoreactivity levels were negatively and positively correlated with egg laying latency and reproductive success (offspring/brood/pair), respectively. At the same time, we found no effect on the hypothalamic expression of orexigenic (NPY) and anorexigenic (CART) peptides, or ZENK protein (ie, the neuronal activity marker). These results suggest the involvement of reproductive neuropeptides, with putative roles for GnRH‐II and TH, in the food‐time‐dependent effect on reproductive performance, albeit with subtle sex differences, in diurnal zebra finches, which possess the ability to reproduce year‐round, in a manner similar to other continuously breeding vertebrates.

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“…Apart from association of circadian rhythm to diseases, the timing and duration of therapy, also known as Chronotherapy, is crucial in determining the efficacy of the drugs as different types of chemotherapy drugs kill cells at different stages of the cell cycle. Several animal studies have also shown the possible impact of the loss of night on brain health and functions in an emerging ecosystem in which other diurnal species including humans may be inadvertently exposed to an illuminated night such as in an overly lighted metropolitan urban habitat (Taufique and Kumar 2016).…”

mentioning

confidence: 99%

Introduction: special issue on “Rhythms, Calendar and Biological Processes”

Kumar

2017

Biological Rhythm Research

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Differential activation and tyrosine hydroxylase distribution in the hippocampal, pallial and midbrain brain regions in response to cognitive performance in Indian house crows exposed to abrupt light environment

Cited by 28 publications

References 57 publications

Illuminated night alters hippocampal gene expressions and induces depressive‐like responses in diurnal corvids

Illuminated night alters hippocampal gene expressions and induces depressive‐like responses in diurnal corvids

Changes in brain peptides associated with reproduction and energy homeostasis: Putative roles of gonadotrophin‐releasing hormone‐II and tyrosine hydroxylase in determining reproductive performance in response to daily food availability times in diurnal zebra finches

Introduction: special issue on “Rhythms, Calendar and Biological Processes”

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