Different Types of Physical Activity and Metabolic Control in People With Type 1 Diabetes Mellitus

Abstract

BackgroundThe aim of presented cross-sectional study was to determine the association of different types of physical activity (PA) with metabolic control in people with type 1 diabetes.Materials and MethodsA total of 109 adult subjects with type 1 diabetes were asked to complete the non-exercise activity thermogenesis (NEAT) questionnaire, the hypoglycemia questionnaire, and the World Health Organization Global PA Questionnaire (GPAQ) which was used to assess moderate PA (MPA) and vigorous PA (VPA).ResultsNEAT score (p < 0.001) and total duration of work as assessed with GPAQ (p = 0.007) were positively associated with chronic glycemic control when controlled for sex, BMI, and continuous glucose monitoring system (CGMS) use. We could not confirm such association with total leisure time PA (LTPA) assessed with GPAQ (p = 0.443), though. Multivariate regression model controlled for sex showed positive effects of HbA1c (p = 0.011) and age (p = 0.035), and negative effect of NEAT score (p = 0.001) on BMI. Systolic blood pressure was positively associated with duration of MPA (p = 0.009) and VPA (p = 0.012), but not with NEAT score (p = 0.830) when controlled for sex and BMI. NEAT score and VPA were positively associated with HDL levels when controlled for sex and BMI. Controlled for sex and BMI, higher values of VPA were significantly associated with lower levels of total cholesterol (p = 0.009) and LDL (p = 0.005).ConclusionHigher levels of NEAT are associated with some favorable metabolic effects in adult people with type 1 diabetes, but may also present an additional burden for them with more challenging environment regarding glycemic control.

Diabetic Cardiomyopathy and Ischemic Heart Disease: Prevention and Therapy by Exercise and Conditioning

“…High-intensity interval training induced an increased oxidative capacity of skeletal muscle and blunts the rates of glucagon breakdown, which could be a possible protective effect against hypoglycemia after exercise [139]. However, a recent study published by Štotl et al [140], conducted in a cohort of 109 T1DM patients, demonstrated that physical activity in leisure time did not affect glycemic control measured and glycated hemoglobin in T1DM individuals.…”