2022
DOI: 10.3389/fsurg.2022.978798
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Different treatments for 3- or 4-part proximal humeral fractures in the elderly patients: A Bayesian network meta-analysis of randomized controlled trials

Abstract: BackgroundProximal humeral fractures are the third most common fracture in the body, and their incidence is rising year by year as the population ages. However, the treatment of the proximal humerus in parts 3 and 4 is still debatable, necessitating a network meta-analysis to determine the best treatment for each treatment modality.MethodsWe searched PubMed, Embase, Cochrane Library for randomized controlled trials on proximal humeral fractures up to June 21, 2022. We performed data extraction and literature q… Show more

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Cited by 3 publications
(2 citation statements)
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References 39 publications
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“…These age-related changes in MC may be responsible for the increased risk of proximal humeral fractures (PHFs) and higher fracture severity (1,4,6,7). Furthermore, incompetent MC, i.e., fragile with impaired strength, due to advanced age is also associated with a higher risk of fracture complications (8)(9)(10)(11)(12). Conversely, elderly patients with severe osteopenia treated with integrity restoration of MC could achieve a satisfactory prognosis, similar to that of younger patients (13-16).…”
Section: Introductionmentioning
confidence: 99%
“…These age-related changes in MC may be responsible for the increased risk of proximal humeral fractures (PHFs) and higher fracture severity (1,4,6,7). Furthermore, incompetent MC, i.e., fragile with impaired strength, due to advanced age is also associated with a higher risk of fracture complications (8)(9)(10)(11)(12). Conversely, elderly patients with severe osteopenia treated with integrity restoration of MC could achieve a satisfactory prognosis, similar to that of younger patients (13-16).…”
Section: Introductionmentioning
confidence: 99%
“…1,4 While most PHFs are minimally displaced or nondisplaced, for which conservative management is usually recommended, 1,5 controversy exists regarding optimal management of displaced and comminuted PHF. 6,7 There are a number of fixation techniques, such as tension-band routing, locking plate fixation, and intramedullary nailing over the past decade [8][9][10][11][12][13][14] ; however, no single technique demonstrated evidence-based superiority. Although locking plate fixation is considered as the standard treatment, complication rates are still unsatisfactory.…”
Section: Introductionmentioning
confidence: 99%