2016
DOI: 10.1007/s11695-016-2449-9
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Different Supplementation Regimes to Treat Perioperative Vitamin B12 Deficiencies in Bariatric Surgery: a Systematic Review

Abstract: Vitamin B12 dosage in multivitamin supplementation in the current literature is quite variable. There is no consensus about the optimal treatment of vitamin B12 deficiency. A systematic literature search on different supplementation regimes to treat perioperative vitamin B12 deficiencies in bariatric surgery was performed. The methodological quality of ten included studies was rated using the Newcastle Ottawa scale and ranged from moderate to good. The agreement between the reviewers was assessed with a Cohen'… Show more

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Cited by 30 publications
(22 citation statements)
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“…Discussion continues as to the optimal dosage and route of supplementation 133–135 . Some studies suggest that supplementation with high doses of oral vitamin B12 may prevent or reduce the development of deficiency 34,135 .…”
Section: Vitamin and Mineral Supplementationmentioning
confidence: 99%
“…Discussion continues as to the optimal dosage and route of supplementation 133–135 . Some studies suggest that supplementation with high doses of oral vitamin B12 may prevent or reduce the development of deficiency 34,135 .…”
Section: Vitamin and Mineral Supplementationmentioning
confidence: 99%
“…The diets of patients suffering from nutritional deficiencies should be supplemented. According to practical experience, an oral vitamin B 12 supplement administered in a daily dose of 350 µg offers effective treatment for most patients [ 30 , 31 ].…”
Section: Dietary Managementmentioning
confidence: 99%
“…The most prescribed drugs were from the ATC groups B, A and C. The group B was prominent mainly because of the widespread use of vitamin B12. Although vitamin B12 is known to be important for nerve function, there is no consensus about the optimal dose of vitamin B12 supplementation 19,20 . It is obvious that prescribing of a very high dose of vitamin B12 (2.5 mg versus 20 µg according to the DDD for hypovitaminosis) in off-label indication 21 (e.g., diabetic neuropathy and radiculopathy) led vitamin B12 to the first position.…”
Section: Discussionmentioning
confidence: 99%