Different source of commercial vegetable oils may regulate metabolic, inflammatory and redox status in healthy rats

Gomes, Sttefany Viana; Dias, Bruna Vidal; Pereira, Renata Rebeca; Lúcio, Karine de Pádua; Souza, Débora Maria Soares de; Talvani, André; Brandão, Geraldo Célio; Cosenza, Gustavo Pereira; Queiroz, Karina Barbosa de; Costa, Daniela Caldeira

doi:10.1016/j.jff.2020.103780

Cited by 4 publications

(1 citation statement)

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“…In a study conducted by Gomes et al [36], healthy rats were supplemented with linseed oil, and the authors observed no significant differences between the control and supplemented groups in the serum content of total cholesterol and triglycerides. In another study, Wistar rats were supplemented with hot-and cold-pressed linseed oil, and both supplements caused a significant decrease in triglycerides, total cholesterol and the LDL fraction, as well as an increase in the HDL level, compared to a control group and a group fed a hypercholesterolemic diet [37].…”

Section: Blood Lipid Profilementioning

confidence: 94%

Different Sources of Omega-3 Fatty Acid Supplementation vs. Blood Lipid Profiles—A Study on a Rat Model

Sokoła-Wysoczańska,

Czyż,

Wyrostek

2024

Foods

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Dyslipidemia is a serious condition affecting an increasing number of people, and thus, preventive measures, including supplementation, are being developed. We aimed to compare the effect of linseed oil, its ethyl esters and fish oil supplementation on the serum lipid profiles of rats fed a high-fat diet. Wistar rats were divided into nine groups. Four of them were fed a high-fat diet for the whole experiment, four groups were fed a high-fat diet before the supplementation period and then the control one with supplements, and one was fed a control diet without supplements. The whole experiment lasted 12 weeks. A significant reduction in blood triglycerides, total cholesterol and the LDL fraction was noted in supplemented groups compared to the controls, especially in groups supplemented with ethyl esters of linseed oil and linseed oil compared to fish oil groups. The results were also more beneficial in groups where, in addition to supplementation, there was also a diet change from a high-fat diet to a control diet during the supplementation period. We may conclude that supplementation with omega-3 fatty acids, combined with a healthy diet, may be a good way of preventing or alleviating dyslipidemia.

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Section: Blood Lipid Profilementioning

confidence: 94%