Different shades of cholesterol: Gold nanoparticles supported on MoS2 nanoribbons for enhanced colorimetric sensing of free cholesterol

Nirala, Narsingh R.; Pandey, Shobhit; Bansal, Anushka; Singh, Vijay Kumar; Mukherjee, Bratindranath; Saxena, Preeti S.; Srivastava, Anchal

doi:10.1016/j.bios.2015.06.043

Cited by 103 publications

(41 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…They suggested that the excellent catalytic activity of the MoS 2 –Au@Pd composite should be attributed to not only the intrinsic catalytic activity of MoS 2 , but also the metal–metal and metal–support interactions. A complete study on the catalytic mechanism of noble‐metal‐nanostructure‐decorated TMD nanosheets towards TMB by H 2 O 2 was reported by Nirala et al They found that the MoS 2 –Au composite exhibited synergistically enhanced intrinsic peroxidase‐like catalytic activity. By introduction of cholesterol oxidase in the sensing system, a sensitive colorimetric sensor for cholesterol detection in human serum samples was established.…”

Section: Tmd Nanosheets and Their Composite‐based Optical Sensorsmentioning

confidence: 99%

Recent Advances in Sensing Applications of Two‐Dimensional Transition Metal Dichalcogenide Nanosheets and Their Composites

Ping

Fan

Sindoro

et al. 2017

Adv Funct Materials

218

136

View full text Add to dashboard Cite

of 18) 1605817As a newly emerging class of nanomaterials, 2D TMD nanosheets possess a unique layered structure and large surface areas, as well as outstanding physical, chemical, optical, and electronic properties, which holds great potential for applications in catalysis, [37] sensing, [38] optics, [39] and energy. [40] In this review, we will focus on the introduction of state of the art sensing applications for 2D TMD nanosheets and their composites. In particular, different sensing strategies together with signal-transducing mechanisms in sensors based on 2D TMD nanosheets and their composites are thoroughly discussed. Our aim is to demonstrate a complete concept in this rapidly emerging research area and to address basic knowledge, opportunities, and challenges in this promising field. We expect that more 2D TMD nanosheets and their composites, as well as more sensing strategies, will be explored in this research field, enabling the fabrication of more accurate sensing devices for practical applications. TMD Nanosheets and Their Composite-Based Electrochemical SensorsThe electrochemical method has been extensively recognized as a powerful tool for fast access to biochemical information in complex samples due to its easy operation, fast response, high sensitivity, and low cost. Inspired by the use of graphene as transducers in electrochemical sensors, [41][42][43] researchers have attempted to use 2D TMD nanosheets as a transducer layer. Their good conductivity, large surface area, fast electron transfer kinetics, high signal/noise ratio, and, more importantly, their feasibility for forming composites, make 2D TMD nanosheets attractive as for electrochemical sensors. [44][45][46][47][48][49][50] Table 1 summarizes the recent progress of electrochemical sensors based on 2D TMD nanosheets and their composites. TMD Nanosheets as a Transducer Layer in Electrochemical SensorsIn 2012, our group developed a single-layer TMD-nanosheetbased electrochemical sensor, in which a single-layer MoS 2nanosheet-modified glassy carbon electrode was directly used for selective detection of dopamine in the presence of uric acid Two-dimensional (2D) transition metal dichalcogenide (TMD) nanosheets, such as MoS 2 , WS 2 , etc., are attracting increasing interest due to their intriguing physical, chemical, electronic, and optical properties. Success in development of methods for large-scale production of 2D TMD nanosheets and their composites has given great potential for various novel applications. In this review, recent progress in sensing applications of 2D TMD nanosheets and their composites is introduced. Moreover, different sensing strategies and signal-transducing mechanisms for sensing devices based on 2D TMD nanosheets and their composites are also summarized and discussed.

show abstract

Section: Tmd Nanosheets and Their Composite‐based Optical Sensorsmentioning

confidence: 99%

Recent Advances in Sensing Applications of Two‐Dimensional Transition Metal Dichalcogenide Nanosheets and Their Composites

Ping

Fan

Sindoro

et al. 2017

Adv Funct Materials

218

136

View full text Add to dashboard Cite

show abstract

“…[1][2] However,a bnormal cholesterol levels in physiology is relatedt om any diseases includingh ypolipoproteinemia, septicemia, brain thrombosis, arteriosclerosis, and so on. [3][4][5] Besides cholesterol, H 2 O 2 represents the oxidative stress in living tissues. The ab-normalH 2 O 2 level in tissues can potentially induce various types of damage to cellular compartments, consequently causing aging, atherosclerosis, cancer,a nd renal diseases.…”

Section: Introductionmentioning

confidence: 99%

“…[57][58][59] However,u pt on ow,t here are only af ew reportsa bout the peroxidase-like activity of MoS 2 for colorimetric detection of cholesterol. [4][5] For example, Nirala et al reportedacolorimetric detection of free cholesterol by using MoS 2 -Au composites. [4] Guo et al also reported an interesting work for the simple colorimetric detectiono fc holesterol in serum by using purchased raw MoS 2 nanosheets withouts urface modification.…”

Section: Introductionmentioning

confidence: 99%

“…[4][5] For example, Nirala et al reportedacolorimetric detection of free cholesterol by using MoS 2 -Au composites. [4] Guo et al also reported an interesting work for the simple colorimetric detectiono fc holesterol in serum by using purchased raw MoS 2 nanosheets withouts urface modification. [5] The sensitivity of this platform is high with ar apid detection process.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Synthesis of Surface‐Modification‐Oriented Nanosized Molybdenum Disulfide with High Peroxidase‐Like Catalytic Activity for H₂O₂ and Cholesterol Detection

Yin

et al. 2018

Chemistry A European J

View full text Add to dashboard Cite

Abnormal H O and cholesterol levels are closely related to many diseases. This work reports a facile process for the synthesis of oxidized glutathione (GSSG)-modified MoS nanosheets (MoS -GSSG NSs). The biocompatible MoS -GSSG NSs have good dispersibility and high affinity to the substrate 3,3',5,5'-tetramethylbenzidine (TMB), which is beneficial for improving peroxidase-like catalytic activity of MoS . The high peroxidase-like activity of MoS -GSSG NSs was applied as a robust nanoplatform for low-cost, rapid, and highly effective colorimetric detection of H O and total/free cholesterol. Moreover, the peroxidase-like catalytic mechanism was studied by the steady-state kinetics method. The catalytic activity was remarkably high at a wide range of pH (2.4-7.0) and temperature values (25-70 °C). The cholesterol was catalyzed by cholesterol oxidase (ChOx) in the presence of O to generate H O , which oxidized TMB to generate a blue-colored product (oxTMB) under the catalysis of MoS -GSSG NSs. The detection limit (DL) of total cholesterol and H O was as low as 5.36 and 0.51 μm, respectively. The linear ranges for detecting cholesterol and H O were from 5.36 to 800 μm and from 0.51 to 50 μm, respectively. This method was also successfully applied to the detection of cholesterol in serum. The detection concentration of total cholesterol was consistent with that of the value detected by the blood biochemical method used in the clinic.

show abstract

“…[20] Although the introduction of MoS 2 effectively improves dispersibility and reduces air voids and gaps, there are still two shortcomings in its practical applications. [23] Therefore, considering all these factors, an effective way to improve the thermal conductivity and electrical conductivity is to deposit highly thermally conductive and highly reactive materials on the MoS 2 substrate. [22] The second is that the effective transfer of electrons is limited, as the electrons move laterally along the layered structure of the MoS 2 nanosheet, resulting in poor electrical conductivity of the MoS 2 .…”

Section: Introductionmentioning

confidence: 99%

Tailoring Highly Thermal Conductive Properties of Te/MoS₂/Ag Heterostructure Nanocomposites Using a Bottom‐Up Approach

Yan

et al. 2018

Adv Elect Materials

View full text Add to dashboard Cite

Ever‐increasing packaging and power densities of modern electronic devices in the present “More‐than‐Moore” technology era demand higher performance thermal interface materials (TIMs). However, conventional composite TIMs require higher loading to achieve better thermal conductive property, resulting in a mechanical problem. The poor wetting property of matrix loading materials further increases the interfacial thermal resistance (ITR). In this work, a one‐step hydrothermal method is employed to grow 2D molybdenum disulfide (MoS2) nanosheets on a tellurium (Te) nanowire skeleton and silver (Ag) nanoparticles are further decorated on MoS2 nanosheets via the photoreduction method. The in‐plane thermal conductivity of the final nanocomposite reaches as high as 10.4 W m−1 K−1, which is 4,160% higher than that of a pure epoxy resin and one order of magnitude higher than that of conventional polymeric nanocomposites. The 3D interconnected heat transferring network of Te/MoS2/Ag greatly enhances the thermal stability of the composite in practical applications. The rational materials design concept may contribute to the development of new types of high‐performance thermal management materials.

show abstract

Different shades of cholesterol: Gold nanoparticles supported on MoS2 nanoribbons for enhanced colorimetric sensing of free cholesterol

Cited by 103 publications

References 37 publications

Recent Advances in Sensing Applications of Two‐Dimensional Transition Metal Dichalcogenide Nanosheets and Their Composites

Recent Advances in Sensing Applications of Two‐Dimensional Transition Metal Dichalcogenide Nanosheets and Their Composites

Synthesis of Surface‐Modification‐Oriented Nanosized Molybdenum Disulfide with High Peroxidase‐Like Catalytic Activity for H₂O₂ and Cholesterol Detection

Tailoring Highly Thermal Conductive Properties of Te/MoS₂/Ag Heterostructure Nanocomposites Using a Bottom‐Up Approach

Contact Info

Product

Resources

About

Different shades of cholesterol: Gold nanoparticles supported on MoS2 nanoribbons for enhanced colorimetric sensing of free cholesterol

Cited by 103 publications

References 37 publications

Recent Advances in Sensing Applications of Two‐Dimensional Transition Metal Dichalcogenide Nanosheets and Their Composites

Recent Advances in Sensing Applications of Two‐Dimensional Transition Metal Dichalcogenide Nanosheets and Their Composites

Synthesis of Surface‐Modification‐Oriented Nanosized Molybdenum Disulfide with High Peroxidase‐Like Catalytic Activity for H2O2 and Cholesterol Detection

Tailoring Highly Thermal Conductive Properties of Te/MoS2/Ag Heterostructure Nanocomposites Using a Bottom‐Up Approach

Contact Info

Product

Resources

About

Synthesis of Surface‐Modification‐Oriented Nanosized Molybdenum Disulfide with High Peroxidase‐Like Catalytic Activity for H₂O₂ and Cholesterol Detection

Tailoring Highly Thermal Conductive Properties of Te/MoS₂/Ag Heterostructure Nanocomposites Using a Bottom‐Up Approach