Different Psychosocial Factors Are Associated with Seasonal and Perennial Allergies in Adults: Cross-Sectional Results of the KORA FF4 Study

Harter, Katharina; Hammel, Gertrud; Krabiell, Lisa; Linkohr, Birgit; Peters, Annette; Schwettmann, Lars; Ring, Johannes; Johar, Hamimatunnisa; Ladwig, Karl‐Heinz; Traidl‐Hoffmann, Claudia

doi:10.1159/000499042

Cited by 14 publications

(12 citation statements)

References 38 publications

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“…Also, there was a positive association between depression and perennial allergies, as well as a negative association between anxiety and perennial allergies. This study supported the relevance of psychosocial factors in association with allergies [8].…”

Section: Introductionsupporting

confidence: 85%

Personality Profiles in Patients With Allergic Rhinitis

Soleimani

Jalali

Bour

2020

Caspian J Neurol Sci

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Background: Psychological factors can be associated with allergic disorders. However, no particular personality pattern associated with these disorders has yet been identified. Objectives: This study aimed at comparing the personality profiles of patients with perennial allergic rhinitis and normal controls. Materials & Methods: This cross-sectional study was done on 50 adult people with persistent allergic rhinitis for at least one year and 50 age- and sex-matched normal controls that completed the Minnesota Multiphasic Personality Inventory-2 (MMPI-2). A multivariate covariance analysis (MANCOVA) was carried out to discover possible personality differences between the two groups. The data were analyzed by SPSS v. 19 software. Results: The results of the MMPI showed no significant difference between the two groups in the validity scales (P=0.29). The most common modal validity presentation style in both groups was neutral self-presentation. The MANCOVA analysis showed significantly high scores on the hypochondriasis (F=18.13, P<0.005, partial η2 =0.16) and hysteria scales in allergic rhinitis subjects (F=8.68, P=0.04, partial η2 =0.08) compared with normal controls. The most common profiles with high scores in the allergic rhinitis subjects were schizophrenia (52%, P<0.01) and hypochondriasis (50%, P<0.01). These scales emphasized the feelings of isolation and discomfort in allergic people. The frequency of psychasthenia scale, which measures long lasting anxiety, was significantly different between the two groups (40% in allergic rhinitis subjects vs. 10% in normal controls, odds ratio=6 [95%CI 1.9-22.3], P<0.001). Conclusion: The score of psychological health is lower among allergic people than in normal contro

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Section: Introductionsupporting

confidence: 85%

Personality Profiles in Patients With Allergic Rhinitis

Soleimani

Jalali

Bour

2020

Caspian J Neurol Sci

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“… 113,114 Also, in adults with allergies, psychoneuroimmunologic mechanisms might play an important role. 115 An association of anxiety and depression with allergies was reported in many studies 116,117 …”

Section: Factors Modulating Allergic Diseasementioning

confidence: 95%

Advances and novel developments in environmental influences on the development of atopic diseases

Alkotob

Cannedy

Harter

et al. 2020

Allergy

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Both genes and the environment shape human health and disease. Although IgE-mediated allergic diseases (atopic diseases) have a genetic component and are more prevalent in individuals with a family history of allergic disease, the observed rapid increases in allergic diseases suggest that environmental factors are the predominant driving forces behind these increases rather than genetic alterations. 1,2 Common atopic diseases include atopic dermatitis, food allergy, allergic rhinitis, and allergic asthma. Human diets and lifestyle have undergone major alterations. The exposome, which is the sum total of all the exposures of an individual in a lifetime, has undergone major shifts in the last few decades, affecting human health and disease. A number of environmental factors have been implicated in the increased prevalence of allergic diseases. Predominant among them are increased exposure to pollutants and decreased exposure to microbes and parasitic infections. Air pollution has increased significantly in the last few decades. The hygiene hypothesis suggests that increased hygiene and lack of exposure to microbes and parasitic infections at an early age prevents the necessary stimulus to train the immune system to develop tolerogenic responses. Lifestyle factors,

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“…The stress level coming from the psychosocial environment is another extrinsic factor, which is correlated with disease symptom severity and exacerbation, 6 leading to a vicious circle as AE is a strong psychological burden for patients 44,45 . In line, psychological interventions had a positive effect on AE severity in a meta‐analysis and were also associated with other allergic diseases 46,47 …”

Section: Atopic Eczema As An Environmental Diseasementioning

confidence: 96%

A new era of atopic eczema research: Advances and highlights

Hülpüsch

Weins

Traidl‐Hoffmann

et al. 2021

Allergy

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Atopic eczema (AE) or atopic dermatitis (AD) is an inflammatory skin disease with involvement of genetic, immunological and environmental factors which are highly interconnected. 1,2 The heterogenic disease can be separated into different phenotypes and clinical presentations defined by the ethnicity, disease onset, disease severity, chronic vs acute, intrinsic vs extrinsic (IgE level), paediatric vs adult and inflammatory signature. [3][4][5] A common feature of all subtypes is a tremendous psychosocial burden for all patients with AE. 6 Prevalence varies by area and is reported to be 15-20% in children in Europe, persisting in up to 5-10% of adults. [7][8][9] Although severe cases are less abundant than mild or moderate disease pattern, 2% of affected children are severely suffering. 7,9 Therefore, AE remains to be a high and even increasing socio-economic burden in the United States and in Europe, 10,11 whereas slightly decreasing numbers were reported over the last few years in Japan. 12 Children often overcome atopic eczema, but set off on the so-called 'atopic march', that is begin a classic 'allergy career'. Scientifically, AE is a risk factor for the development of allergies. These are primarily type I allergies with clinical features such as hay fever and asthma. Allergies are increasingly becoming a widespread disease. Currently, almost every fourth person in Europe suffers from symptoms such as asthma or hay fever and the associated restrictions in everyday life or at work. For society, the reduced ability to perform at school, university and at work means great socio-economic damage.

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Different Psychosocial Factors Are Associated with Seasonal and Perennial Allergies in Adults: Cross-Sectional Results of the KORA FF4 Study

Cited by 14 publications

References 38 publications

Personality Profiles in Patients With Allergic Rhinitis

Personality Profiles in Patients With Allergic Rhinitis

Advances and novel developments in environmental influences on the development of atopic diseases

A new era of atopic eczema research: Advances and highlights

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