Different measures of impulsivity in patients with anxiety disorders: A case control study

Carlo, A Del; Benvenuti, M; Fornaro, Michele; Toni, Cristina; Rizzato, Salvatore; Swann, Alan C.; Dell’Osso, Liliana; Perugi, Giulio

doi:10.1016/j.psychres.2011.09.020

Cited by 48 publications

(39 citation statements)

References 55 publications

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“…In our study, PD patients also exhibited more dis-inhibitional/dis-attentional impulsivity ("state impulsivity") compared to healthy controls as measured by the high percentage of commission errors both in the IMT and in the DMT; moreover the levels of inattentive and dis-inhibited impulsivity were higher in cyclothymic subjects than in non cyclothymic ones. These results, taken as a whole, are in line with previous reports by our group [26,27] in patients with ADs belonging to different diagnostic subtypes. AD patients resulted more impulsive than control subjects, in both psychometric and neurocognitive measures [60,61] and impulsivity was highest in patients with both AD and CD [27].…”

Section: Clinical Featuressupporting

confidence: 93%

“…Among the anxiety disorder patients (n= 45) the most frequent diagnosis was panic disorder with (26,55.3%) and without (11,23.4%) agoraphobia; only 1 subject (1.8%) presented agoraphobia without panic disorder. Concerning the other anxiety disorders, 12 patients (25.5%) met diagnostic criteria for obsessive-compulsive disorder, 9 (19.1%) for generalized anxiety disorder and 7 (14.9%) for social anxiety disorder.…”

Section: Diagnostic Distribution Comorbidities and Actual Treatmentmentioning

confidence: 99%

“…The evaluation procedure used has been described in our previous reports [26,27] evaluating impulsivity in a sample of subject belonging to different diagnostic subtypes of anxiety disorders. The present report is focused on a sample of patients with Panic Disorder/agoraphobia as a specific diagnostic subtype.…”

Section: Acknowledgmentsmentioning

confidence: 99%

“…We recently evaluated impulsivity, by two different rating tools, in patients with primary anxiety disorders and control subjects [26,27]. In contrast with the idea that harm avoidance and behavioural inhibition are invariably associated with anxiety disorders, anxious patients resulted more impulsive than control subjects, in both psychometric and neurocognitive measures [26].…”

Section: Introductionmentioning

confidence: 99%

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Impulsivity in anxiety disorders

Carlo

Benvenuti

Dima

et al. 2012

International Clinical Psychopharmacology

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Section: Clinical Featuressupporting

confidence: 93%

Section: Diagnostic Distribution Comorbidities and Actual Treatmentmentioning

confidence: 99%

Section: Acknowledgmentsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Impulsivity in anxiety disorders

Carlo

Benvenuti

Dima

et al. 2012

International Clinical Psychopharmacology

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“…Another important point is that some common axis I comorbidities in patients with BD, such as anxiety disorders, drug addiction, and attention-deficit hyperactivity disorder (ADHD), are associated with high levels of impulsivity. [25][26][27] Given this association, we can speculate that impulsivity in particular, rather than axis I disorder comorbidities in general, may be what drives the higher rates of SB in patients with BD.…”

Section: Discussionmentioning

confidence: 97%

Suicide attempts in bipolar I patients: impact of comorbid personality disorders

Bezerra-Filho

Galvão-de-Almeida

Studart

et al. 2017

Rev. Bras. Psiquiatr.

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Objective: To evaluate the association between personality disorders (PDs) and suicide attempts (SAs) in euthymic patients with type I bipolar disorder (BD). Methods: One-hundred twenty patients with type I BD, with and without history of SA, were evaluated during euthymia. The assessment included a clinical and sociodemographic questionnaire, the Hamilton Depression Rating Scale, the Young Mania Rating Scale, the Barratt Impulsiveness Scale, and Structured Clinical Interviews for DSM-IV Axis I and II Disorders. Logistic regression was employed to determine associations between history of SA and patient characteristics. Results: History of SA was significantly associated with comorbid axis I disorder, rapid cycling, high impulsivity (attentional, motor, non-planning, and total), having any PD, and cluster B and C PDs. Only cluster B PDs, high attentional impulsivity, and lack of paid occupation remained significant after multivariate analysis. Conclusions: Cluster B PDs were significantly associated with SA in patients with type I BD. High attentional impulsivity and lack of gainful employment were also associated with SA, which suggests that some cluster B clinical and social characteristics may exacerbate suicidal behavior in this population. This finding offers alternatives for new therapeutic interventions.

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Trait impulsivity in Juvenile Myoclonic Epilepsy

Shakeshaft

Panjwani

McDowall

et al. 2020

Ann Clin Transl Neurol

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ObjectiveImpulsivity is a multidimensional construct that can predispose to psychopathology. Meta‐analysis demonstrates an association between response impulsivity and Juvenile Myoclonic Epilepsy (JME), a common genetic generalized epilepsy. Here, we test the hypotheses that trait impulsivity is (i) elevated in JME compared to controls; (ii) moderated by specific seizure characteristics; and (iii) associated with psychiatric adverse effects of antiepileptic drugs (AEDs).Methods322 participants with JME and 126 age and gender‐matched controls completed the Barratt’s Impulsiveness Scale (BIS‐brief) alongside information on seizure history and AED use. We compared group BIS‐brief scores and assessed associations of JME BIS‐brief scores with seizure characteristics and AED adverse effects.ResultsThe mean BIS‐brief score in JME was 18.1 ± 4.4 compared with 16.2 ± 4.1 in controls (P = 0.0007). Elevated impulsivity was associated with male gender (P = 0.027), frequent absence seizures (P = 0.0004) and lack of morning predominance of myoclonus (P = 0.008). High impulsivity significantly increased the odds of a psychiatric adverse event on levetiracetam (P = 0.036), but not any other psychiatric or somatic adverse effects.InterpretationTrait impulsivity is elevated in JME and comparable to scores in personality and neurotic disorders. Increased seizure frequency and absence of circadian seizure pattern moderate BIS score, suggesting disruption of both cortico‐striatal and thalamocortical networks as a shared mechanism between seizures and impulsivity in JME. These findings warrant consideration of impulsivity as a distinct target of intervention, and as a stratifying factor for AED treatment in JME, and perhaps other types of epilepsy. The role of impulsivity in treatment adherence and psychosocial outcome requires further investigation.

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Different measures of impulsivity in patients with anxiety disorders: A case control study

Cited by 48 publications

References 55 publications

Impulsivity in anxiety disorders

Impulsivity in anxiety disorders

Suicide attempts in bipolar I patients: impact of comorbid personality disorders

Trait impulsivity in Juvenile Myoclonic Epilepsy

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