Different impulsivity profiles in borderline personality disorder and bipolar II disorder

Bøen, Erlend; Hummelen, Benjamin; Elvsåshagen, Torbjørn; Boye, Birgitte; Andersson, Stein; Karterud, Sigmund; Malt, Ulrik Fredrik

doi:10.1016/j.jad.2014.08.033

Cited by 48 publications

(60 citation statements)

References 57 publications

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“…Impulsivity as assessed with the BIS-11 can be further subdivided into attentional, motor, and non-planning impulsivity, but most clinical studies employ the sum score. Compatible with the clinical observation of frequent impulsive behavior in BPD, higher BIS-11 scores have frequently been observed in BPD patients compared to healthy controls ( Henry et al, 2001 , Berlin et al, 2005 , McCloskey et al, 2009 , Jacob et al, 2010 , Lynam et al, 2011 , Sebastian et al, 2013 ) and also to other patient groups like patients with bipolar II disorder ( Henry et al, 2001 , Wilson et al, 2007 , Boen et al, 2015 ) or even patients with orbitofrontal cortex lesions ( Berlin et al, 2005 ). Several studies of impulsivity in BPD using laboratory tasks have provided direct evidence for behavioral manifestations of impulsivity, such as impaired response inhibition ( Leyton et al, 2001 , Hochhausen et al, 2002 , Rentrop et al, 2008 ), difficulties in feedback-guided decision making ( Haaland and Landro, 2007 , Maurex et al, 2009 , Svaldi et al, 2012 , Mak and Lam, 2013 ), and higher levels of impulsive aggression ( Dougherty et al, 1999 , New et al, 2009 ) in BPD patients compared to clinical and nonclinical controls.…”

Section: Introductionmentioning

confidence: 91%

A negative relationship between ventral striatal loss anticipation response and impulsivity in borderline personality disorder

Herbort

Soch

Wüstenberg

et al. 2016

NeuroImage: Clinical

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Patients with borderline personality disorder (BPD) frequently exhibit impulsive behavior, and self-reported impulsivity is typically higher in BPD patients when compared to healthy controls. Previous functional neuroimaging studies have suggested a link between impulsivity, the ventral striatal response to reward anticipation, and prediction errors. Here we investigated the striatal neural response to monetary gain and loss anticipation and their relationship with impulsivity in 21 female BPD patients and 23 age-matched female healthy controls using functional magnetic resonance imaging (fMRI). Participants performed a delayed monetary incentive task in which three categories of objects predicted a potential gain, loss, or neutral outcome. Impulsivity was assessed using the Barratt Impulsiveness Scale (BIS-11). Compared to healthy controls, BPD patients exhibited significantly reduced fMRI responses of the ventral striatum/nucleus accumbens (VS/NAcc) to both reward-predicting and loss-predicting cues. BIS-11 scores showed a significant positive correlation with the VS/NAcc reward anticipation responses in healthy controls, and this correlation, while also nominally positive, failed to reach significance in BPD patients. BPD patients, on the other hand, exhibited a significantly negative correlation between ventral striatal loss anticipation responses and BIS-11 scores, whereas this correlation was significantly positive in healthy controls. Our results suggest that patients with BPD show attenuated anticipation responses in the VS/NAcc and, furthermore, that higher impulsivity in BPD patients might be related to impaired prediction of aversive outcomes.

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Section: Introductionmentioning

confidence: 91%

A negative relationship between ventral striatal loss anticipation response and impulsivity in borderline personality disorder

Herbort

Soch

Wüstenberg

et al. 2016

NeuroImage: Clinical

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show abstract

“…In those with a BP II disorder there was predominant 'attentional impulsiveness' associated with cognitive disturbances (including impaired concentration, distractibility and racing thoughts) in contrast to the BPD group which demonstrated motor and 'non-planning impulsiveness' characterized by difficulty in planning actions and thinking about consequences. Differing impulsivity profiles have been reported by Boen et al (2015), with BPD compared to BP II participants showing higher scores on the Urgency and (lack of) Perseverance sub-scales of the Urgency, Premeditation, Perseverance and Sensation Seeking Impulsive Behavior Scale (Whiteside and Lynam, 2001). While impulsivity in BPD is considered trait related and a core diagnostic feature, there is evidence of both mood-state dependent (during hypo/manic episodes) and mood state-independent (during euthymic periods) impulsivity in bipolar disorder (Strakowski et al, 2010).…”

Section: Comorbid Bp/bpd Vs Bpd Vs Bp Comparisonsmentioning

confidence: 90%

Emotional dysregulation in those with bipolar disorder, borderline personality disorder and their comorbid expression

Bayes

Parker

McClure

2016

Journal of Affective Disorders

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“…One of the most relevant components is the tendency for rash or regrettable actions because of intense negative affect (Boen et al,2015;Hochhausen, Lorenz & Newman, 2002;Peters, Upton & Baer, 2013;Whiteside & Lynam, 2001;Whiteside, Lynam, Miller & Reynolds, 2005;van Reekum, Links & Fedorov, 1994) while self-regulatory problems are suggested as the underlying cause of impulsivity (Sansone & Wiederman, 2013). Thus, impulsivity is an expected outcome, given the intense negative affect and problems in self-regulation.…”

Section: According To Both the Diagnostic And Statistical Manual For mentioning

confidence: 99%

Mindfulness skills in individuals with borderline personality features: Roles of impulsivity and rejection sensitivity

Emiral-Coskun¹,

Egeci²

2017

GJPR

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The current s tudy explores whether mindfulness mediates the rela tionships between borderline pers onality fea tures and the fa cets of i mpulsi vi ty a nd borderline personality features and rejection sensiti vi ty. The sample consisted of 419 i ndividuals aged between 20 and 39 (M = 26.24, SD = 4.67). Da ta were collected using the Borderline Personali ty Inventory, Mi ndful Attention Awa reness Scale, Urgency, Premedi ta tion, Perseverance, and Sensation-Seeking Impulsi vi ty Scale, and rejection sensiti vi ty ques tionnaire. Mediation anal ysis of the da ta was conducted using the PROCESS ma cro of Ha yes . It was found that mi ndfulness pa rtiall y media tes the relationship between borderline personali ty fea tures and urgency (N = (419) R 2 = (0.22), F = (120.67), p < 0.001), a nd borderline personality fea tures and sensation-seeking fa cets of i mpulsi ve beha viours (N = (419) R 2 = (0.08), F = (36.62), p < 0.001). The study's findings a re dis cussed in rela tion to the exis ting litera ture.Keywords : Borderline personali ty features, mindfulness , i mpulsi vi ty, rejection sensiti vi ty.

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Different impulsivity profiles in borderline personality disorder and bipolar II disorder

Cited by 48 publications

References 57 publications

A negative relationship between ventral striatal loss anticipation response and impulsivity in borderline personality disorder

A negative relationship between ventral striatal loss anticipation response and impulsivity in borderline personality disorder

Emotional dysregulation in those with bipolar disorder, borderline personality disorder and their comorbid expression

Mindfulness skills in individuals with borderline personality features: Roles of impulsivity and rejection sensitivity

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