2022
DOI: 10.3390/endocrines3040049
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Different Expression Patterns of Metabolic Reprogramming Proteins in Testicular Germ Cell Cancer

Abstract: Metabolic reprogramming is an emerging hallmark of cancer, involving the overexpression of metabolism-related proteins, such as glucose and monocarboxylate transporters and intracellular glycolytic enzymes. The biology of testicular germ cell tumors (TGCTs) is very complex, and although their metabolic profile has been scantily explored, some authors have recently reported that the metabolic rewiring of cancer cells resulted in an association with aggressive clinicopathological characteristics. In this study w… Show more

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