Different Age Distribution between Campylobacteriosis and Nontyphoidal Salmonellosis in Hospitalized Korean Children with Acute Inflammatory Diarrhea

Shim, Jung Ok; Chang, Ju Young; Kim, Ahlee; Shin, Sue

doi:10.3346/jkms.2017.32.7.1202

Cited by 6 publications

(6 citation statements)

References 17 publications

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“…varied with age groups: <1 y (0%), 1–5 y (8.9%), 5–10 y (20.0%), and ≥ 11 y (17.1%); the higher the age, the higher the prevalence of Campylobacter spp. These results concurred with previous findings and may be attributed to changes in eating habits with increasing age [ 17 ]. In the present study, among the 20 cases of Campylobacter spp.…”

Section: Discussionsupporting

confidence: 93%

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Evaluation of the BioFire Gastrointestinal Panel to Detect Diarrheal Pathogens in Pediatric Patients

Kim

Cho

et al. 2021

Diagnostics

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Infectious diarrhea is a global pediatric health concern; therefore, rapid and accurate detection of enteropathogens is vital. We evaluated the BioFire® FilmArray® Gastrointestinal (GI) Panel with that of comparator laboratory tests. Stool samples of pediatric patients with diarrhea were prospectively collected and tested. As a comparator method for bacteria, culture, conventional PCR for diarrheagenic E. coli, and Allplex GI-Bacteria(I) Assay were tested. For discrepancy analysis, BD MAX Enteric Bacterial Panel was used. As a comparator method for virus, BD MAX Enteric Virus Panel and immunochromatography was used and Allplex GI-Virus Assay was used for discrepancy analysis. The “true positive” was defined as culture-positive and/or positive results from more than two molecular tests. Of the 184 stool samples tested, 93 (50.5%) were true positive for 128 pathogens, and 31 (16.9%) were positive for multiple pathogens. The BioFire GI Panel detected 123 pathogens in 90 of samples. The BioFire GI Panel demonstrated a sensitivity of 100% for 12 targets and a specificity of >95% for 16 targets. The overall positive rate and multiple pathogen rate among patients in the group without underlying diseases were significantly higher than those in the group with hematologic disease (57.0% vs. 28.6% (p = 0.001) and 20.4% vs. 4.8% (p = 0.02), respectively). The BioFire GI Panel provides comprehensive results within 2 h and may be useful for the rapid identification of enteropathogens.

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Section: Discussionsupporting

confidence: 93%

“…isolation in pediatric patients has increased compared with that of E. coli or Salmonella spp., in our country, and the introduction of multiple molecular assays may be attributed to the increasing rate of Campylobacter spp. isolation [ 16 , 17 ]. In the present study, the rate of detection of Campylobacter spp.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the BioFire Gastrointestinal Panel to Detect Diarrheal Pathogens in Pediatric Patients

Kim

Cho

et al. 2021

Diagnostics

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“…or C. perfringens . 8) The previous study of Shim et al 9) , it was similar to the present study that the incidence and age were significantly higher in patients infected with Campylobacter spp. However, the lack of statistical significance of CRP was different from the present study.…”

Section: Discussionsupporting

confidence: 90%

Clinical manifestation of Campylobacter enteritis in children

Bae

Lee

et al. 2018

Korean J Pediatr

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PurposeTimely antibiotic therapy in selected cases of diarrhea associated with bacterial infections can reduce the duration and severity of illness and prevent complications. The availability of a predictive index before identification of causative bacteria would aid in the choice of a therapeutic agent.MethodsThe study included patients admitted to the pediatrics unit at Konyang University Hospital for acute inflammatory diarrhea from August 1, 2015 to July 31, 2016 who underwent multiplex polymerase chain reaction testing. Of 248 patients, 83 had positive results. The clinical symptoms and blood test results were examined in 61 patients with Campylobacter spp. (25 patients), Salmonella spp. (18 patients), and Clostridium perfringens (18 patients) infections. The mean age of the 61 patients (male:femal=31:30) was 84.0±54.8 months, and the mean hospital stay was 4.6±1.7 days.ResultsThere were no statistical differences in sex, age, clinical symptoms, or signs. Patients with Campylobacter infection were significantly older (P=0.00). C-reactive protein (CRP) levels in patients with Campylobacter infection were higher than those in the other 2 groups, at 9.6±6.1 mg/dL. The results of receiver-operating characteristic curve analysis showed that the cutoff age was ≥103.5 months (sensitivity, 72%; specificity, 86%) and the CRP cutoff level was ≥4.55 mg/dL (sensitivity, 80%; specificity, 69%).ConclusionAge (≥103.5 months) and higher CRP level (≥4.55 mg/dL) were good predictors of Campylobacter enterocolitis. If neither criterion was met, Campylobacter enterocolitis was unlikely (negative predictive value 97.2%). When both criteria were met, Campylobacter enterocolitis was highly likely.

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“…Although most of the NTS in this study were isolated from patients 5-years-ofage, a considerable number of patients were 5-yearsof-age. A similar trend has been reported in other Asian countries (11)(12)(13)(14).…”

Section: Discussionsupporting

confidence: 89%

Prevalence of Multidrug Resistant Salmonellae with Increasing Frequency of <i>Salmonella enterica</i> Serovars Kentucky and Virchow among Hospitalized Diarrheal Cases in and around Delhi, India

Sharma¹,

Kumar

Sarkar

et al. 2020

Jpn J Infect Dis

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Different Age Distribution between Campylobacteriosis and Nontyphoidal Salmonellosis in Hospitalized Korean Children with Acute Inflammatory Diarrhea

Cited by 6 publications

References 17 publications

Evaluation of the BioFire Gastrointestinal Panel to Detect Diarrheal Pathogens in Pediatric Patients

Evaluation of the BioFire Gastrointestinal Panel to Detect Diarrheal Pathogens in Pediatric Patients

Clinical manifestation of Campylobacter enteritis in children

Prevalence of Multidrug Resistant Salmonellae with Increasing Frequency of <i>Salmonella enterica</i> Serovars Kentucky and Virchow among Hospitalized Diarrheal Cases in and around Delhi, India

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