Differences of cardiovascular risk assessment in clinical practice using SCORE and SCORE2

Abstract

ObjectiveCardiovascular risk estimation is an essential step to reduce the onset of adverse cardiovascular events. For this purpose, the Systematic Coronary Risk Evaluation (SCORE) risk chart method was used in Europe. In 2021, the SCORE2 algorithm was released, bringing changes in the calculation methodology. This study assessed and compared the level of cardiovascular risk in a population aged 40–65 years using the SCORE and SCORE2 methodologies.MethodsThis cross-sectional study included a total of 85 802 patients in Hungary. Cardiovascular risk levels were determined using the SCORE and SCORE2 risk estimation methods.ResultsUsing SCORE, 97.7% of men aged 40–50 years were classified as low–moderate risk, which decreased to 32.4% using SCORE2. Using SCORE, 100% of women aged 40–50 years were classified as low–moderate risk, compared with 75.6% using SCORE2. Using SCORE, 36.8% of men aged 50–65 years were classified as high risk and 14.8% as very high risk, and 5.4% of women aged 50–65 years were classified as high risk and 0.5% as very high risk. In this age group, using SCORE2, 50% of men were classified as high risk and 25.8% as very high risk, and 38.8% of women were classified as high risk and 11.9% as very high risk.ConclusionsWhen the SCORE2 method was used instead of SCORE 43.91% of the whole population were classified with a higher level of risk, which represents a radical increase in the number of patients with high or very high cardiovascular risk.

Validation of SCORE2 on a sample from the Russian population and adaptation for the very high cardiovascular disease risk region

“…Researchers were dissatisfied with the fact that based on SCORE2, a significant proportion of the population is considered at the very high risk instead of the previous low–moderate or high risk according to SCORE. That would lead to the unmanageable load in the primary healthcare systems of the countries of SCORE2 very high risk region [ 17 ]. In our study, an enormous fraction of 63% of ESSE-RF men among those who met SCORE2 target population criteria were classified into a very high 10-year CVD risk group.…”

Comparative Assessment of the Risks of Fatal and Non-Fatal Cardiovascular Events Using the Score/Score-2 Score in Patients With Cardiovacular Pathology

“…С целью предотвращения постоянной высокой тенденции смертности населения от сердечно-сосудистых событий с 2003 года базовой оценкой определения 10-летнего риска фатальных сердечно-сосудистых осложнений у пациентов без сопутствующих сердечно-сосудистых заболеваний принято считать шкалу SCORE, предложенную Европейским обществом кардиологов (ESC) [9]. Данная шкала учитывала показатели: пол, возраст, табакокурение, уровень общего холестерина и систолического артериального давления.…”