Differences in the Korea Acute Myocardial Infarction Registry Compared with Western Registries

Abstract

The Korea Acute Myocardial Infarction Registry (KAMIR) is the first nationwide registry that reflects current therapeutic approaches and acute myocardial infarction (AMI) management in Korea. The results of the KAMIR demonstrated different risk factors and responses to medical and interventional treatments. The results indicated that the incidence of ST-elevation myocardial infarction (STEMI) was relatively high, and that the prevalence of dyslipidemia was relatively low with higher triglyceride and lower high-density lipoprotein cholesterol levels. Percutaneous coronary intervention (PCI) rates were high for both STEMI and non-ST-elevation myocardial infarction (NSTEMI) with higher use of drug-eluting stents (DESs). DES were effective and safe without increased risk of stent thrombosis in Korean AMI patients. Triple antiplatelet therapy, consisting of aspirin, clopidogrel, and cilostazol, was effective in preventing adverse clinical outcomes after PCI. Statin therapy was effective in Korean AMI patients, including those with very low levels of low-density lipoprotein cholesterol and those with cardiogenic shock. The KAMIR score had a greater predictive value than Thrombolysis in Myocardial Infarction (TIMI) and Global Registry of Acute Coronary Events (GRACE) scores for long-term mortality in AMI patients. Based on these results, the KAMIR will be instrumental for establishing new therapeutic strategies and effective methods for secondary prevention of AMI and guidelines for Asian patients.

Lack of prognostic significance for major adverse cardiac events of soluble suppression of tumorigenicity 2 levels in patients with ST-segment elevation myocardial infarction

“…Acute ST-segment elevation myocardial infarction (STEMI) makes a significant contribution to morbidity and mortality in many parts of the world [1][2][3][4]. It is well known that early diagnosis and proper management, especially delay from the onset of symptoms to revascularization are important for long-term prognosis [5,6].…”

Comparison of First- and Second-Generation Drug-Eluting Stents in Patients with Acute Myocardial Infarction and Prediabetes Based on the Hemoglobin A1c Level

“…A total of 45863 patients from the Korea AMI Registry (KAMIR) who had AMI and underwent successful stent implantation between November 2005 and June 2015 were evaluated. KAMIR is the first nationwide and multicenter registry that included >50 community and teaching hospitals in South Korea since November 2005 [13]. Eligible patients were aged ≥18 years at the time of hospital admission.…”

Aspirin for Primary Prevention of Cardiovascular Disease

“… 47 48 In addition, Asian patients have a relatively low prevalence rate of obesity and dyslipidemia compared to Western patients. 47 49 50 Most risk calculation methods that are currently available are from the data of Western populations, and it is difficult to conclude that simply applying these risk scores to Asian populations is possible. Therefore, those with a very high risk of CVD should optionally be recommended to take aspirin by considering evidence, bleeding risks, and individual patient characteristics.…”