Differences in the Cardiovascular Risk Factor Profiles in Patients With Transient Global Amnesia and Transient Ischemic Attack

Abstract

The purpose of the study is to examine the characteristics of cardiovascular risk factors in patients with transient global amnesia and transient ischemic attack.
 Materials and Methods. A study was conducted of patients with transient global amnesia and transient ischemic attack admitted to the primary vascular department, City Clinical Hospital named after N.I. Pirogov (January 2021 – March 2023). All patients were examined for main cardiovascular risk factors, such as age, male gender, coronary artery disease, atrial fibrillation, previous stroke, diabetes mellitus, smoking, arterial hypertension, dyslipidemia, increased hematocrit, left ventricular hypertrophy, valvular heart disease, and atherosclerosis of the brachiocephalic arteries. Statistical data processing was carried out with Data Analysis package, Microsolft Excel 2019. One-way ANOVA test was used to calculate statistical significance between the groups. For all data, statistical significance was p<0.05.
 Results. We examined 37 patients with transient global amnesia and 103 patients with transient ischemic attack. In patients with transient global amnesia, such cardiovascular risk factors as male gender, coronary artery disease, stroke, and atrial fibrillation were significantly less common, and the level of total cholesterol was significantly higher. There were no statistically significant differences in the incidence of other risk factors.
 Conclusion. Cardiovascular risk factor profiles differ in patients with transient global amnesia and those with transient ischemic attacks. The identified risk factors make it possible to focus on the developmental mechanisms of these pathologies and optimize primary and secondary prevention techniques.