Differences in susceptibility of early life stages of rainbow trout (Salmo gairdneri) to environmental pollutants

Leeuwen, Cornelis van; Griffioen, P.S.; Vergouw, W.H.A.; Maas-Diepeveen, J.L.

doi:10.1016/0166-445x(85)90036-0

Cited by 98 publications

(52 citation statements)

References 30 publications

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“…-the yet improperly developed enzymatic system in embryos, -differences in metabolism pathways, -different processes of absorption of the substance into the organism (Van Leeuwen et al 1985).…”

Section: Discussionmentioning

confidence: 99%

Assessment of diclofenac LC50 reference values in juvenile and embryonic stages of the zebrafish (Danio rerio)

Prášková¹,

Voslářová²,

Široká³

et al. 2011

Polish Journal of Veterinary Sciences

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The aim of the study was to compare the acute toxicity of diclofenac to juvenile and embryonic stages of the zebrafish (Danio rerio). Acute toxicity tests were performed on the aquarium fish Danio rerio, which is one of the model organisms most commonly used in toxicity testing. The tests were performed using a semi-static method according to OECD guideline No. 203 (Fish, acute toxicity test). Embryo toxicity tests were performed in zebrafish embryos (Danio rerio) in compliance with OECD No. 212 methodology (Fish, short-term toxicity test on embryo and sac-fry stages). The results were subjected to a probit analysis using the EKO-TOX 5.2 programme to determine 96hLC50 and 144hLC50 (median lethal concentration, 50% mortality after a 96 h or 144 h interval, respectively) values of diclofenac. The statistical significance of the difference between LC50 values in juvenile and embryonic stages of Danio rerio was tested using the Mann-Whitney non-parametric test implemented in the Unistat 5.1 programme. The LC50 mean value of diclofenac was 166.6 ± 9.8 mg/L in juvenile Danio rerio, and 6.11 ± 2.48 mg/L in embryonic stages of Danio rerio. The study demonstrated a statistically higher sensitivity to diclofenac (P<0.05) in embryonic stages compared to the juvenile fish.

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Section: Discussionmentioning

confidence: 99%

Assessment of diclofenac LC50 reference values in juvenile and embryonic stages of the zebrafish (Danio rerio)

Prášková¹,

Voslářová²,

Široká³

et al. 2011

Polish Journal of Veterinary Sciences

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“…Within a species, different life stages may experience differential sensitivity to many contaminants (McKim, 1977;Van Leeuwen et al, 1985). For example, when DDT was aerially applied over a forest in New Brunswick in the 1960s to control spruce budworm, Atlantic salmon parr (2+ fish) numbers decreased by 40%, but young of the year (0+) salmon numbers decreased by 98% (Elson, 1967).…”

Section: Differential Effects Of Pesticidesmentioning

confidence: 99%

Changes in Salmonid Communities Associated with Pesticide Runoff Events

2005

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Two agricultural runoff events involving the pesticide azinphos-methyl occurred in July 2002 on the Wilmot River, Prince Edward Island, Canada, resulting in the death of thousands of fish. The fish communities from three sites on this river had been sampled in 2001, permitting comparisons of brook trout (Salvelinus fontinalis) and rainbow trout (Oncorhynchus mykiss) populations before and after the events. Samples taken immediately after the runoff events suggested that brook trout suffered higher mortality than rainbow trout. Young-of-the-year fish were more affected than older age classes for both species. Sampling in 2003, a year after the pesticide runoff events, revealed salmonid communities that were still skewed towards rainbow trout, and a decrease in the 1+ age class density (2002's young of the year) at affected sites. These results suggest a differential effect of the pesticide azinphos-methyl on salmonid species and age classes under natural conditions, and a subsequent change in population and community structure. The possibility of these pesticide runoff events selecting for rainbow trout, an exotic species, is a consideration in management of agriculturally impacted rivers.

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“…In the whole-body accumulation experiments the rate constants were estimated from a kinetic model which has been described in more detail in a previous paper [10]. The set of equations, however, had to be extended in order to comprise biotransformation processes.…”

Section: Discussionmentioning

confidence: 99%

“…In this case, the steady-state bioconcentration factor (BCF: l/kg) equals k,/k2. The parameter estimation procedure is described in [ 10].…”

Section: Discussionmentioning

confidence: 99%

Uptake, distribution and retention of zineb and ziram in rainbow trout (Salmo gairdneri)

et al. 1986

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SUMMARYIn short-term static bioaccumulation experiments with 14C-labelled zinc ethylenebisdithiocarbamate (zineb) and zinc dimethyldithiocarbamate (ziram) both compounds were rapidly disseminated through the tissues. Whole-body accumulation was low, with bioconcentration factors < 100. Whole-body elimination was rapid with 457o and 257o of the initial radioactivity from ziram and zineb, respectively, being retained by the end of the 16-day deputation period. Pigmented tissues appeared to be major distribution sites as well. This may be related to the affinity of the compounds and/or their degradation products to melanin or to complexation with phenoloxidase, a copper-containing enzyme involved in melanin synthesis. Autoradiography also revealed a high labelling of thyroid follicles. The results show that dithiocarbamates are selectively localized in various tissues, reported to be the target organs for their toxic action. The observed differences in toxicokinetics between zineb and ziram may, in part, explain the differences in toxicity to fish between ethylenebisdithiocarbamates and dialkyldithiocarbamates.

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Differences in susceptibility of early life stages of rainbow trout (Salmo gairdneri) to environmental pollutants

Cited by 98 publications

References 30 publications

Assessment of diclofenac LC50 reference values in juvenile and embryonic stages of the zebrafish (Danio rerio)

Assessment of diclofenac LC50 reference values in juvenile and embryonic stages of the zebrafish (Danio rerio)

Changes in Salmonid Communities Associated with Pesticide Runoff Events

Uptake, distribution and retention of zineb and ziram in rainbow trout (Salmo gairdneri)

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