Differences in sensitivity to the anthelmintic praziquantel by the skin-parasitic monogeneans Benedenia seriolae and Neobenedenia girellae

Anthelmintic effects of 75 ppm hydrogen peroxide treatment on the monogeneans Benedenia seriolae , Neobenedenia girellae , and Zeuxapta japonica infecting the skin and gills of greater amberjack Seriola dumerili

“…The source of B. seriolae, its propagation on S. quinqueradiata and the obtainment of oncomiracidia has been described (Hirazawa et al, 2013). Four uninfected individuals of S. dumerili, weighing 150 g on average, were transferred to a 100-l tank and were acclimated at 25 ± 0.5°C for 1 week.…”

“…Oral administration of praziquantel-supplemented feed has proven an efficient way of eliminating B. seriolae in S. dumerili (Hirazawa et al, 2013) and Zeuxapta seriolae in Seriola lalandi (Williams et al, 2007), but the effectiveness of this treatment is markedly poor against N. girellae in S. dumerili and Seriola quinqueradiata (Hirazawa et al, 2013). An alternative way to control capsalid monogeneans infecting fish is to submerge fish in freshwater, which dislodges the parasites (Leong, 1997).…”

Albendazole, levamisole and ivermectin are effective against monogeneans of Colossoma macropomum (Pisces: Serrasalmidae)

“…In intensive fish farming, managing and controlling helminth infections pose a constant challenge, since these tasks are greatly complicated by the limited availability of licensed anthelmintic drugs (Morales‐Serna et al, ; Zuskova et al, ) with varying degrees of effectiveness. Anthelmintic drugs such as albendazole, mebendazole, ivermectin, levamisole and praziquantel have been employed for the control and treatment against monogenean parasites that infest farmed fish (Hirazawa, Akiyama, & Umeda, ; Hirazawa, Ohtaka, & Hata, ; Kim & Choi, ; Martins, Onaka, Moraes, & Fujimoto, ; Morales‐Serna et al, ; Onaka, Martins, & Moraes, ; Santamarina, Tojo, Ubeira, Quinteiro, & Sanmartin, ; Sitjà‐Bobadilla, Felipe, & Alvarez‐Pellitero, ; Zhang et al, ). Parasite infections can be controlled and treated by eliminating developmental stages in hosts, thus interrupting the life cycle of parasites (Bader, Chelladurai, Starling, Jones, & Brewer, ).…”

“…Various studies have demonstrated ivermectin toxicity in fish (Mladineo, Marsic‐lucic, & Buzancic, ; Santamarina et al, ; Thiripurasundari, Sathya, Uma, Srinivasan, & Rajasekar, ; Varó et al, ), whereas clinical concentrations of albendazole, mebendazole, levamisole and praziquantel present a low toxicity (Hirazawa et al, ; Kim & Choi, ; Martins et al, ; Onaka et al, ). However, these anthelminthics have not been assayed to ascertain their effectiveness in controlling monogeneans of Colossoma macropomum (tambaqui), a fish of great economic importance to aquaculture from the Amazon.…”

Mebendazole dietary supplementation controls Monogenoidea (Platyhelminthes: Dactylogyridae) and does not alter the physiology of the freshwater fish Colossoma macropomum (Cuvier, 1818)

“…On the other hand, other drugs have been tested to treat monogeneans such as mebendazole, bitionol and praziquantel used as therapeutic bath and in the diet (Schmahl and Taraschewski, 1987;Kim and Choi, 1998;Martins et al, 2001;Hirazawa et al, 2013). The mebendazole is considered the most effective drug with low toxicity (Buchmann and Bresciani, 1994;Martins et al, 2001).…”