Differences in right and left ventricular remodeling after transcatheter closure of atrial septal defect among adults

Wu, En‐Ting; Akagi, Teiji; Taniguchi, Masaru; Maruo, Takeshi; Sakuragi, Satoru; Otsuki, Shinichi; Okamoto, Yoshio; Sano, Shunji

doi:10.1002/ccd.21075

Cited by 58 publications

(54 citation statements)

References 23 publications

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“…The unloading of the right ventricle may cause a decrease in RV function immediately after the procedure [2]. This phenomenon might also be related to myocardial compliance of the right ventricle [29]. We found that tissue Doppler-derived left ventricular Tei index was significantly decreased during the follow-up period.…”

Section: Myocardial Performance Indices Of Rv and LVmentioning

confidence: 93%

Incomplete RV Remodeling After Transcatheter ASD Closure in Pediatric Age

et al. 2015

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Published data showing the intermediate effect of transcatheter device closure of atrial septal defect (ASD) in the pediatric age-group are scarce. The objective of the study was to assess the effects of transcatheter ASD closure on right and left ventricular functions by tissue Doppler imaging (TDI). The study included 37 consecutive patients diagnosed as ASD secundum by transthoracic echocardiography and TEE and referred for transcatheter closure at Cairo University Specialized Pediatric Hospital, Egypt, from October 2010 to July 2013. Thirty-seven age- and sex-matched controls were selected. TDI was obtained using the pulsed Doppler mode, interrogating the right cardiac border (the tricuspid annulus) and lateral mitral annulus, and myocardial performance index (MPI) was calculated at 1-, 3-, 6- and 12-month post-device closure. Transcatheter closure of ASD and echocardiographic examinations were successfully performed in all patients. There were no significant differences between two groups as regards the age, gender, weight or BSA. TDI showed that patients with ASD had significantly prolonged isovolumetric contraction, relaxation time and MPI compared with control group. Decreased tissue Doppler velocities of RV and LV began at one-month post-closure compared with the controls. Improvement in RVMPI and LVMPI began at 1-month post-closure, but they are still prolonged till 1 year. Reverse remodeling of right and left ventricles began 1 month after transcatheter ASD closure, but did not completely normalize even after 1 year of follow-up by tissue Doppler imaging.

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Section: Myocardial Performance Indices Of Rv and LVmentioning

confidence: 93%

Incomplete RV Remodeling After Transcatheter ASD Closure in Pediatric Age

et al. 2015

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“…Several studies and our own experience have demonstrated clinical benefits and positive right-heart remodeling, with reduction of the right ventricular end-diastolic diameter. (8)(9)(10)(11)(12)(13)(14)(15)(16)(17) However, few studies were published considering geriatric patients, who older than 70 years. (18)(19)(20)(21) In this aged population, not only catheter closure of ASD but also surgical closure has been reported very limited experiences, little data are published on functional results.…”

Section: Introductionmentioning

confidence: 99%

Atrial Septal Defect Closure in Geriatric Patients

Akagi¹

2012

Atrial Septal Defect

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“…These values approached to those in healthy controls (0.39±0.04 a year after vs. 0.38±0.04 in healthy controls, P=ns) indicating that closure of ASD improves global RV function [41]. Wu et al [42] reported that while LV Tei index improved soon after the procedure, RV Tei index worsened until 1 month after the procedure, then recovered by the 3-month follow-up visit indicating that Device closure of ASDs caused rapid improvement of LV function, but RV function underwent transient deterioration, probably due to delayed changes in RV ventricular mass in the face of acute volume reduction [42]. Our study showed non-significant difference between RV Tei index 1year after ASD closure and normal values.…”

Section: Discussionmentioning

confidence: 68%

Intermediate Outcome of Transcatheter Closure of Secundum Atrial Septal Defect on Cardiac Remodeling in Egyptian Children and Adults

Ammar¹,

Arab²,

Hammady³

et al. 2016

JCCR

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Background: Atrial septal defects (ASDs) are the second most common congenital lesion in adults. ASD closure is followed by symptomatic improvement and regression of pulmonary artery pressure (PAP), reduction in right heart volume overload and hence the prevalence of arrhythmias, thus quantification of the RV function is an important prognostic factor. Tissue Doppler and strain imaging are helpful tools for the assessment of RV systolic and diastolic function. Results:At the 1 year follow up of transcatheter ASD closure, the RVEDD had decreased from 22.93±5.889 mm to 18±4.06 mm(P=0.000), and the LVEDD had increased from 33.23±5.393 mm to 36.27±6.75 mm(P=0.001). Mean PAP decreased from 18.37±4.796 mmHg to 14.77±4.75 mmHg (P=0.022). RVSP decreased from 28.9±4.425 mmHg to 15.83±4.17 mmHg (P=0.000). Regarding electrocardiography, the P wave duration decreased from 107.13±19.62 ms to 77±14.18 ms (P=0.000) and the PR interval decreased from 177.97±21.932 ms to 160.33±26.06 ms (P=0.000).The QRS duration decreased from 134.40± 4.97 ms to a mean of 119.87±4.12 ms (P=0.000). All the patients had normal sinus rhythm before closure and no one developed arrhythmia until 1 year after closure. 50 % of the patients had normal RV size at the 1-year follow up. Tricuspid annular velocities, longitudinal strain, and strain rate measurement showed no significant difference as compared to normal values, which suggest improvement of the RV systolic and diastolic function after transcatheter closure. Conclusion:Transcatheter ASD closure leads to a significant improvement in heart cavity dimensions and RV function and reversal of electrical and mechanical changes. Novel parameters for assessment of RV function are promising and appear to be helpful for the assessment of RV function and its response to correction of volume

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Differences in right and left ventricular remodeling after transcatheter closure of atrial septal defect among adults

Cited by 58 publications

References 23 publications

Incomplete RV Remodeling After Transcatheter ASD Closure in Pediatric Age

Incomplete RV Remodeling After Transcatheter ASD Closure in Pediatric Age

Atrial Septal Defect Closure in Geriatric Patients

Intermediate Outcome of Transcatheter Closure of Secundum Atrial Septal Defect on Cardiac Remodeling in Egyptian Children and Adults

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