Differences in imeglimin response in subgroups of patients with type 2 diabetes stratified by data‐driven cluster analysis: A post‐hoc analysis of imeglimin clinical trial data
Katsuhiko Hagi,
Kenji Kochi,
Hirotaka Watada
et al.
Abstract:AimTo explore differences in imeglimin response among type 2 diabetes (T2D) patient clusters using data‐driven cluster analysis.MethodsData‐driven cluster analysis (non‐hierarchical k‐means clustering) was performed on randomized, double‐blind, imeglimin monotherapy and adjunctive (to insulin) therapy trials based on four baseline variables: (1) disease duration; (2) body mass index (BMI); (3) HbA1c; and (4a) homeostatic model assessment of β‐cell function (HOMA‐β) (monotherapy trials) or (4b) insulin total da… Show more
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