Abstract:Background: Insomnia and hypersomnia are common in bipolar disorder (BD) but it is unclear whether genetic factors influence this association.Stratifying by bipolar subtypes could elucidate the nature of this association and inform research on sleep and BD. We therefore aimed to determine whether polygenic risk scores (PRS) for insomnia, daytime sleepiness and sleep duration differ according to bipolar subtypes (bipolar I disorder, BD-I or bipolar II disorder, BD-II). Methods: In this case-control study, we us… Show more
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