Difference research of pectins extracted from tobacco waste by heat reflux extraction and microwave-assisted extraction

Zhang, Maolan; Zeng, Guoming; Pan, Yuzhu; Qi, Na

doi:10.1016/j.bcab.2018.06.022

Cited by 25 publications

(6 citation statements)

References 27 publications

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“…The medicinal parts of ginseng (roots and flower buds) are increasingly popular as dietary supplements due to the current trend towards a holistic approach to healthcare. Although numerous extraction methods exist in the typical home, including supercritical fluid, ultrasonic wave, microwave, and heat reflux (Dai and Orsat, 2010; Wang et al, 2010; Ajavakom et al, 2012; Johner et al, 2018; Zhang et al, 2018) traditional water extraction and powdering are the most frequently used methods to obtain the medicinal benefits of ginseng via ingestion (Nabavi et al, 2018; Taban and Saharkhiz, 2015). The main effective constituents of ginseng are the ginsenosides, of which Rb1, a protopanaxadiol (PPD)-type ginsenoside with a dammarane-type triterpenoid as an aglycone, is the main bioactive component (Quan et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

Rb1, the Primary Active Ingredient in Panax ginseng C.A. Meyer, Exerts Antidepressant-Like Effects via the BDNF–Trkb–CREB Pathway

et al. 2019

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Panax ginseng C.A. Meyer (Araliaceae), a popular tonic and dietetic herbal medicine, has been traditionally prescribed in China and other countries to treat affective disorders. The medicinal parts of ginseng, the roots and flower buds, have become increasingly popular as dietary supplements due to the current holistic healthcare trend. We have investigated for the first time the antidepressive actions of the different medicinal parts, namely, the main roots, fibrous roots, and flower buds (in water extract and powder), of garden-cultivated ginseng through behavioral and drug-induced tests in mice. The water extracts, but not the powders of ginseng fibrous roots, flower buds, and main roots (1.5 g of crude drug per kilogram, p.o.), significantly reduced the immobility time in the forced swim test (FST) and tail suspension test (TST); moreover, the water extracts enhanced the 5-hydroxytryptophan (5-HTP)-induced head-twitch response and antagonized the action of reserpine in the mouse. We then explored the antidepressive mechanism of action of the ginsenoside Rb1 (Rb1) related to the brain-derived neurotrophic factor (BDNF) and its downstream proteins in mice exposed to chronic unpredictable mild stress (CUMS). Treatment with Rb1 (20 mg/kg, p.o.) for 21 days significantly attenuated the CUMS-induced decrease in the activities of BDNF, tropomyosin-related kinase B (TrkB), protein kinase B (AKT), extracellular regulatory protein kinase (ERK), and cyclic adenosine monophosphate (cAMP) response element binding protein (CREB) in the mouse hippocampal CA3 region and prefrontal cortex (PFC). Interestingly, treatment with the novel TrkB antagonist ANA-12 (0.5 mg/kg, i.p.) did not alter the level of BDNF but significantly blocked the antidepressive effects of Rb1 on proteins downstream of BDNF in CUMS-treated mice. These results suggest that BDNF–TrkB–CREB signaling may be involved in the antidepressive mechanism of the action of Rb1.

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Section: Introductionmentioning

confidence: 99%

Rb1, the Primary Active Ingredient in Panax ginseng C.A. Meyer, Exerts Antidepressant-Like Effects via the BDNF–Trkb–CREB Pathway

et al. 2019

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“…The DE and chemical parameters are listed in Tables and , respectively. The SFHP had a pH value of 4.93, whereas high methoxyl pectin extracted from tobacco had a pH of 2.63 . Similarly, the obtained SFHP had a DE between 17.7 and 19.4%, which was comparatively lower than other sunflower head pectins extracted by ammonium oxalate and sodium citrate with DE values of 31.7 and 49%, respectively. , Note that the SWE process may have decreased the DE .…”

Section: Resultsmentioning

confidence: 87%

Extraction of Low Methoxyl Pectin from Fresh Sunflower Heads by Subcritical Water Extraction

Jing

Wang

et al. 2020

ACS Omega

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Subcritical water extraction (SWE) of pectin from fresh sunflower heads was optimized using the response surface methodology (RSM). The optimal conditions for the maximum yield of pectin (6.57 ± 0.6%) were found to be a pressure of 8 bar, temperature of 120 °C, time of 20 min, and liquid–solid ratio (LSR) of 7 mL/g. The degree of esterification (DE) of pectin was analyzed by titrimetry and Fourier transform infrared (FTIR) methods, which was low methoxyl pectin. The molecular weight (M w), galacturonic acid (GalA) content, and surface tension of pectin were 11.50 kDa, 82%, and 45.38 mN/m (1.5% w/v), respectively. Moreover, thermogravimetric (TG) and differential scanning calorimetry (DSC) analysis confirmed that pectin had excellent thermal stability. FTIR and 1H NMR spectra confirmed its structure. This study demonstrated that SWE could be used as a productive and environmentally friendly method for extracting pectin from fresh sunflower heads.

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“…The vapor trickles down to the flask, thus controlling the temperature of the reaction. The technology has been preferred due to its simplicity and easy operation (Zhang et al 2018a ). The technology has found application in extracting many natural, phytochemical compounds and essential oils (Gao and Liu 2005 ; Aliboudhar and Tigrine-Kordjani 2014 ).…”

Section: Extraction Methods Of Polyphenolsmentioning

confidence: 99%

Techniques and modeling of polyphenol extraction from food: a review

et al. 2021

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There is a growing demand for vegetal food having health benefits such as improving the immune system. This is due in particular to the presence of polyphenols present in small amounts in many fruits, vegetables and functional foods. Extracting polyphenols is challenging because extraction techniques should not alter food quality. Here, we review technologies for extracting polyphenolic compounds from foods. Conventional techniques include percolation, decoction, heat reflux extraction, Soxhlet extraction and maceration, whereas advanced techniques are ultrasound-assisted extraction, microwave-assisted extraction, supercritical fluid extraction, high-voltage electric discharge, pulse electric field extraction and enzyme-assisted extraction. Advanced techniques are 32-36% more efficient with approximately 15 times less energy consumption and producing higher-quality extracts. Membrane separation and encapsulation appear promising to improve the sustainability of separating polyphenolic compounds. We present kinetic models and their influence on process parameters such as solvent type, solid and solvent ratio, temperature and particle size.

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Difference research of pectins extracted from tobacco waste by heat reflux extraction and microwave-assisted extraction

Cited by 25 publications

References 27 publications

Rb1, the Primary Active Ingredient in Panax ginseng C.A. Meyer, Exerts Antidepressant-Like Effects via the BDNF–Trkb–CREB Pathway

Rb1, the Primary Active Ingredient in Panax ginseng C.A. Meyer, Exerts Antidepressant-Like Effects via the BDNF–Trkb–CREB Pathway

Extraction of Low Methoxyl Pectin from Fresh Sunflower Heads by Subcritical Water Extraction

Techniques and modeling of polyphenol extraction from food: a review

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