Difference in DNA Methylation between Cleft Lip and Cleft Lip and Palate
Ruby Riana Asparini,
David S. Perdanakusuma,
Retno Handajani
et al.
Abstract:It is suspected that environmental exposure to non-syndromic oral clefts, which includes cleft lip (CL), cleft lip and palate (CLP) has an effect on epigenetic mechanisms, particularly deoxyribonucleic acid (DNA) methylation. DNA methylation will be expressed during facial morphogenesis and have an impact on facial development. This study aimed to observe differences in DNA methylation between CL and CLP, between CL mothers and CLP mothers, and correlation between CL and CL mothers, CLP and CLP mothers. Th… Show more
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