Difference between MCF-ExTEM and MCF-FibTEM (ROTEM) and platelet activity after cardiopulmonary bypass

Duchemin, G.; Kiss, Gabriel; Guéret, Gildas; Rossignol, Benoît; Corre, Olivier Le; Kerautret, P.; Blouch, M. T.; Abgrall, Jean-François; Goerlinger, Klaus; Arvieu, C. C.

doi:10.1097/00003643-200606001-00304

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“…1, 2). Clot firmness (A10 or MCF) in ExTEM and FibTEM have to be compared to differentiate between fibrinogen deficiency/polymerisation disorders and thrombocytopenia/platelet function disorders [111,110,117]. Heparin effects as well as a protamine overdosage can be detected or excluded by comparing the clotting times of InTEM and HepTEM [22,116,118].…”

Section: Rotem Parameters and Reference Rangementioning

confidence: 99%

“…Based on our experience with POC coagulation management, we developed -in cooperation with our colleagues from the university clinics of Frankfurt/M. and Hannover -an algorithm for ROTEM and Multiplate based coagulation management in cardiac surgery which was first presented at the Deutscher Anästhesie-Con- gress 2007 in Hamburg [22,96,106,117,121,138,139] (fig. 3, 4).…”

Section: Algorithm For Poc Coagulation Management In Cardiac Surgerymentioning

confidence: 99%

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Perioperative Coagulation Management and Control of Platelet Transfusion by Point-of-Care Platelet Function Analysis

Görlinger

Jámbor²,

Hanke

et al. 2007

Transfus Med Hemother

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About one third of all blood components transfused intraoperatively is used in cardiac surgery, whereas mortality of cardiosurgical patients correlates nearly linear with the number of transfused units of packed red blood cells. Acquired platelet function disorders play a major role in perioperative bleeding in cardiac surgery. Therefore, the use of point-of-care-suitable platelet function analyzers seems to be reasonable in this field. Methods: Platelet function analyzer PFA-100®, rotational thrombelastometry (ROTEM®), and multiple platelet function analyzer (Multiplate®) are in principle applicable for point-of-care testing. Since these three analyzers monitor different aspects of platelet function and have different limitations, the selection of the right test system depends on the right question. Results: Perioperative use of platelet function analyzers is helpful in prediction of blood loss in cardiac surgery. Perioperative usage of blood components and their respective costs can be reduced by an appropriate coagulation management. Conclusion: Algorithms for perioperative coagulation management based on point-of-care testing permit a fast diagnostic and goal-directed therapy of coagulation and functional platelet disorders. The possibility to reduce the mortality of patients and the overall cost for hospital stay is subject of further studies.

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Section: Rotem Parameters and Reference Rangementioning

confidence: 99%

Section: Algorithm For Poc Coagulation Management In Cardiac Surgerymentioning

confidence: 99%

Perioperative Coagulation Management and Control of Platelet Transfusion by Point-of-Care Platelet Function Analysis

Görlinger

Jámbor²,

Hanke

et al. 2007

Transfus Med Hemother

View full text Add to dashboard Cite

show abstract

Difference between MCF-ExTEM and MCF-FibTEM (ROTEM) and platelet activity after cardiopulmonary bypass

Cited by 1 publication

References 0 publications

Perioperative Coagulation Management and Control of Platelet Transfusion by Point-of-Care Platelet Function Analysis

Perioperative Coagulation Management and Control of Platelet Transfusion by Point-of-Care Platelet Function Analysis

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