Diferencias entre cirugía en bloque y enucleación en el tratamiento del sarcoma retroperitoneal

López, José Antonio González; Raventós, Vicente Artigas; Blanco, Manuel Rodríguez; Pousa, Antonio López; Bagué, Sílvia; Abellan, M. Lopez; Folch, Manel Trías

doi:10.1016/j.ciresp.2014.02.002

Cited by 9 publications

(3 citation statements)

References 19 publications

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“…Surgical resection remains the standard treatment for LGFMS, with wide en bloc surgical resection being the most effective [5, 19] and enucleation, which was performed, being optimal for eliminating functional impairment of the anal sphincter muscle. We performed no adjuvant treatments because such practices to LGFMS are not conventional.…”

Section: Discussionmentioning

confidence: 99%

Low-grade fibromyxoid sarcoma of the external anal sphincter: a case report

et al. 2017

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BackgroundLow-grade fibromyxoid sarcoma (LGFMS) is a rare soft tissue tumor that has a tendency to grow in the deep soft tissue of the trunk and extremities. Despite its benign appearance, the tumor has a high recurrence rate and metastatic potential. LGFMS in the perineal space is rare, and only a few cases have been reported. We present the first case of LGFMS to be located at the external anal sphincter.Case presentationA 27-year-old male patient admitted to our Surgical Department with perianal pain and swollen for a year. The digital rectal examination revealed a perianal mass. Oral metronidazole and analgesia were prescribed on suspicion of perianal abscess failed to alleviate the symptom; hence, the patient was scheduled for surgery. Intraoperative diagnosis revealed an encapsulated tumor in the external anal sphincter that extended from the perianal region orally to the pararectal space. The results of immunohistochemistry (MUC4 staining) and FUS gene rearrangement by fluorescence in situ hybridization confirmed the diagnosis of LGFMS.ConclusionsThis case is unique in terms of the location of the rare soft tissue tumor. Although LGFMS is considered low grade, its unpredictable behavior necessitates a long-term follow-up.

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Section: Discussionmentioning

confidence: 99%

Low-grade fibromyxoid sarcoma of the external anal sphincter: a case report

et al. 2017

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“…En bloc resection of the tumour including adjacent organs is the only curative treatment for RPS, negative margins being the main prognostic factor (IV B) [ 59 ]. Post-operative radiation is an option in highly selected patients with well-defined target regions (IV B) [ 60 ].…”

Section: Therapeutic Considerations For Specific Sts Subtypesmentioning

confidence: 99%

Clinical practice guidelines for the diagnosis and treatment of patients with soft tissue sarcoma by the Spanish group for research in sarcomas (GEIS)

Muro

Álava

Artigas

et al. 2015

Cancer Chemother Pharmacol

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Soft tissue sarcomas (STS) constitute an uncommon and heterogeneous group of tumours, which require a complex and specialized multidisciplinary management. The diagnostic approach should include imaging studies and core needle biopsy performed prior to undertaking surgery. Wide excision is the mainstay of treatment for localized sarcoma, and associated preoperative or postoperative radiotherapy should be administered in high-risk patients. Adjuvant chemotherapy was associated with a modest improvement in survival in a meta-analysis and constitutes a standard option in selected patients with high-risk STS. In metastatic patients, surgery must be evaluated in selected cases. In the rest of patients, chemotherapy and, in some subtypes, targeted therapy often used in a sequential strategy constitutes the treatment of election. Despite important advances in the understanding of the pathophysiology of the disease, the advances achieved in therapeutic results may be deemed still insufficient. Moreover, due to the rarity and complexity of the disease, the results in clinical practice are not always optimal. For this reason, the Spanish Group for Research on Sarcoma (GEIS) has developed a multidisciplinary clinical practice guidelines document, with the aim of facilitating the diagnosis and treatment of these patients in Spain. In the document, each practical recommendation is accompanied by level of evidence and grade of recommendation on the basis of the available data.

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“…El tratamiento de estos tumores es la resección quirúrgica con márgenes oncológicos, ya que en caso de pasar por tumor la recidiva es la regla. Esto último, junto al subtipo histológico y su grado de diferenciación, son los principales factores pronósticos de sobrevida (6).…”

Section: Introductionunclassified