Diethylhydrogensilyl-Cyclic Diethylsilylene (DEHS-DES) Derivatives in Gas Chromatography-Mass Spectrometry (GC/MS) of Prostanoids. II. : GC and GC/MS Properties of DEHS-DES Derivative of Thromboxane B&lt;SUB&gt;2&lt;/SUB&gt; Methyl Ester-Methyloxime

Ishibashi, Masataka; Watanabe, Keiko; Miyazaki, Hiroshi; Krolik, Stefan

doi:10.1248/yakushi1947.106.12_1118

Cited by 2 publications

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“…Thromboxane B 2 ( 262 ) formed a methyl ester/methyloxime/diethylsilylene/DES derivative with structure 263 (Fig. a, Scheme ) (Ishibashi et al, ) following opening of the tetrahydropyran ring. Unlike the spectra of the derivatized steroids, no molecular ion was present and the [M − C 2 H 5 • ] + ion was of low relative abundance.…”

Section: Other Silyl Derivativesmentioning

confidence: 99%

“…Ions produced by α‐cleavage and loss of OCH 3 • ( m/z 552, [M − 31] + ) were prominent and the base peak ( m/z 269, pb ) was produced by cleavage of the diethylsilylene ring (Scheme , Fig. a) (Ishibashi et al, ).…”

Section: Other Silyl Derivativesmentioning

confidence: 99%

“…Proposed mechanism (Ishibashi et al., ) for the formation of the fragment ion at m/z 269 ( pb ) from the methyl ester/methyloxime/diethylsilylene/DES derivative of thromboxane B 2 ( 263 ).…”

Section: Other Silyl Derivativesmentioning

confidence: 99%

“…Proposed mechanism (Ishibashi et al, 1987b) for the formation of the fragment ion at m/z 157 (pf/pg) from the methyl ester/ diethylsilylene/DES derivative of prostaglandin F. SCHEME 192. Proposed mechanism (Ishibashi et al, 1986a) for the formation of the fragment ion at m/z 269 (pb) from the methyl ester/ methyloxime/diethylsilylene/DES derivative of thromboxane B 2 (263).…”

Section: Ive3 Cyclic-di-tert-butylsilylene Derivativesmentioning

confidence: 99%

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Mass Spectrometric Fragmentation of Trimethylsilyl and Related Alkylsilyl Derivatives

Harvey

Vouros

2019

Mass Spectrometry Reviews

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This review describes the mass spectral fragmentation of trimethylsilyl (TMS) and related alkylsilyl derivatives used for preparing samples for analysis, mainly by combined gas chromatography and mass spectrometry (GC/MS). The review is divided into three sections. The first section is concerned with the TMS derivatives themselves and describes fragmentation of derivatized alcohols, thiols, amines, ketones, carboxylic acids and bifunctional compounds such as hydroxy‐ and amino‐acids, halo acids and hydroxy ethers. More complex compounds such as glycerides, sphingolipids, carbohydrates, organic phosphates, phosphonates, steroids, vitamin D, cannabinoids, and prostaglandins are discussed next. The second section describes intermolecular reactions of siliconium ions such as the TMS cation and the third section discusses other alkylsilyl derivatives. Among these latter compounds are di‐ and trialkyl‐silyl derivatives, various substituted‐alkyldimethylsilyl derivatives such as the tert‐butyldimethylsilyl ethers, cyclic silyl derivatives, alkoxysilyl derivatives, and 3‐pyridylmethyldimethylsilyl esters used for double bond location in fatty acid spectra. © 2019 Wiley Periodicals, Inc. Mass Spec Rev 0000:1–107, 2019

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Section: Other Silyl Derivativesmentioning

confidence: 99%

Section: Other Silyl Derivativesmentioning

confidence: 99%

Section: Other Silyl Derivativesmentioning

confidence: 99%

Section: Ive3 Cyclic-di-tert-butylsilylene Derivativesmentioning

confidence: 99%

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