Dietary zero-dimensional fullerene supplementation improves the meat quality, lipid metabolism, muscle fiber characteristics, and antioxidative status in finishing pigs

Liao, Simeng; Liu, Guang; Tan, Bin; Qi, Ming; Wu, X.; Li, Jianjun; Li, Xiaoqing; Zhu, Changfeng; Huang, Jiamei; Zhang, Shuo; Tang, Yulong; Yin, Yulong

doi:10.1016/j.aninu.2022.06.017

Cited by 4 publications

(3 citation statements)

References 34 publications

(43 reference statements)

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“…ROS accumulation is considered as the principal cause of sperm motility decline during semen preservation [49]. In this regard, CF-C 60 has been shown to act as a powerful antioxidant that exerts important protective effects in cells [50][51][52]. For example, it has been reported that CF-C 60 protected the gut from the toxic effects of deoxyniurenol by reducing ROS levels and that it signi cantly improved growth performance and immune function in mice [53].…”

Section: Discussionmentioning

confidence: 99%

Carboxyfullerene C60 preserves sperm by enhancing antioxidant capacity and inhibiting apoptosis and harmful bacteria

Li,

Zhang,

Xiao

et al. 2024

Preprint

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Background The current approaches for the preservation of human sperm have several limitations, and there are a lack of effective non-freezing preservation methods. Recently, carboxyfullerene C60 (CF-C60) has gained attention as an important nanocarbon derivative with strong antioxidant and antibacterial activity. This study uses a porcine model to systematically investigate whether CF-C60 can be used for the preservation of sperm. Results The results indicate that CF-C60 supplementation can preserve sperm quality during storage at 17°C. This effect is attributable to improvement in the antioxidant capacity of sperm through a decrease in the ROS level. Additionally, CF-C60 can maintain mitochondrial function, inhibit sperm apoptosis through the ROS/Cytochrome C/Caspase 3 signaling pathway, and mediate suppression of bacterial growth through the effects of ROS. Finally, the results of artificial insemination experiments indicate that insemination with CF-C60-treated sperm can increase the total number of offspring born and reduce the number of deformed piglets. Conclusions Thus, CF-C60 can preserve sperm quality by inhibition of apoptosis and bacterial growth via a reduction in ROS levels and is safe for use as a component of semen diluent for storage. These findings pave the way for the prospective clinical application of carbon nano-materials as antioxidants for non-freezing sperm preservation methods.

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Section: Discussionmentioning

confidence: 99%

Carboxyfullerene C60 preserves sperm by enhancing antioxidant capacity and inhibiting apoptosis and harmful bacteria

Li,

Zhang,

Xiao

et al. 2024

Preprint

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“…The IMF positively influences sensory quality traits of meat including tenderness, juiciness, and flavor of meats [ 48 ]. In this study, although the supplementation of CB alone did not change IMF content, it increased the IMF content with RPF addition in the diets, suggesting an additive effect between CB and RPF on the IMF content.…”

Section: Discussionmentioning

confidence: 99%

Effects of dietary Clostridium butyricum and rumen protected fat on meat quality, oxidative stability, and chemical composition of finishing goats

Zhang,

Zhang

et al. 2024

J Animal Sci Biotechnol

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Background Clostridium butyricum (CB) is a probiotic that can regulate intestinal microbial composition and improve meat quality. Rumen protected fat (RPF) has been shown to increase the dietary energy density and provide essential fatty acids. However, it is still unknown whether dietary supplementation with CB and RPF exerts beneficial effects on growth performance and nutritional value of goat meat. This study aimed to investigate the effects of dietary CB and RPF supplementation on growth performance, meat quality, oxidative stability, and meat nutritional value of finishing goats. Thirty-two goats (initial body weight, 20.5 ± 0.82 kg) were used in a completely randomized block design with a 2 RPF supplementation (0 vs. 30 g/d) × 2 CB supplementation (0 vs. 1.0 g/d) factorial treatment arrangement. The experiment included a 14-d adaptation and 70-d data and sample collection period. The goats were fed a diet consisted of 400 g/kg peanut seedling and 600 g/kg corn-based concentrate (dry matter basis). Result Interaction between CB and RPF was rarely observed on the variables measured, except that shear force was reduced (P < 0.05) by adding CB or RPF alone or their combination; the increased intramuscular fat (IMF) content with adding RPF was more pronounced (P < 0.05) with CB than without CB addition. The pH24h (P = 0.009), a* values (P = 0.007), total antioxidant capacity (P = 0.050), glutathione peroxidase activities (P = 0.006), concentrations of 18:3 (P < 0.001), 20:5 (P = 0.003) and total polyunsaturated fatty acids (P = 0.048) were increased, whereas the L* values (P < 0.001), shear force (P = 0.050) and malondialdehyde content (P = 0.044) were decreased by adding CB. Furthermore, CB supplementation increased essential amino acid (P = 0.027), flavor amino acid (P = 0.010) and total amino acid contents (P = 0.024) as well as upregulated the expression of lipoprotein lipase (P = 0.034) and peroxisome proliferator-activated receptor γ (PPARγ) (P = 0.012), and downregulated the expression of stearoyl-CoA desaturase (SCD) (P = 0.034). The RPF supplementation increased dry matter intake (P = 0.005), averaged daily gain (trend, P = 0.058), hot carcass weight (P = 0.046), backfat thickness (P = 0.006), concentrations of 16:0 (P < 0.001) and c9-18:1 (P = 0.002), and decreased the shear force (P < 0.001), isoleucine (P = 0.049) and lysine content (P = 0.003) of meat. In addition, the expressions of acetyl-CoA carboxylase (P = 0.003), fatty acid synthase (P = 0.038), SCD (P < 0.001) and PPARγ (P = 0.022) were upregulated due to RPF supplementation, resulting in higher (P < 0.001) content of IMF. Conclusions CB and RPF could be fed to goats for improving the growth performance, carcass traits and meat quality, and promote fat deposition by upregulating the expression of lipogenic genes of Longissimus thoracis muscle.

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“…Nanomaterials with zero dimensions (0D), such as carbon quantum dots, fullerenes, magnetic nanoparticles, up conversion nanoparticles, graphene quantum dots, inorganic quantum dots, noble metal nanoparticles, and polymer nanoparticles, exhibit dimensions that are all within the nanometer scale (less than 100 nm) in each direction [16]. The supplementation of fullerene to the diet has shown to enhance the nutritional value of pigs in the field of livestock agriculture [17].…”

Section: Classifications Of Nanomaterialsmentioning

confidence: 99%

Nanotechnology in agriculture: A review of innovative utilization

Zamri

2023

MNIJ

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The escalating challenges posed by swift population growth, global climate change, and occurrences of disease outbreaks to ensure food security necessitate innovate agricultural improvement techniques. In this intricate milieu, nanotechnology, with its remarkable advancements, emerges as a potent avenue for enhancing sustainable agricultural practices. This review underscores the current landscape of nanotechnology in agriculture, highlighting the classification and synthesis of nanomaterials. Furthermore, insightful applications of nano-based products in agriculture are meticulously elucidated in term of advantages and risks possessed. Notably, the regulatory frameworks from different countries have been addressed to ensure the safety of consumers and the environment. However, despite its myriad benefits, nanotechnology is not exempt from limitations and potential negative consequences, which are explored in the final section of this review. Keywords: nanomaterials, agriculture, nano-based products, regulatory frameworks

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Dietary zero-dimensional fullerene supplementation improves the meat quality, lipid metabolism, muscle fiber characteristics, and antioxidative status in finishing pigs

Cited by 4 publications

References 34 publications

Carboxyfullerene C60 preserves sperm by enhancing antioxidant capacity and inhibiting apoptosis and harmful bacteria

Carboxyfullerene C60 preserves sperm by enhancing antioxidant capacity and inhibiting apoptosis and harmful bacteria

Effects of dietary Clostridium butyricum and rumen protected fat on meat quality, oxidative stability, and chemical composition of finishing goats

Nanotechnology in agriculture: A review of innovative utilization

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