2013
DOI: 10.1155/2013/421832
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Dietary Treatment Options for Depression among Diabetic Patient, Focusing on Macronutrients

Abstract: There is a bidirectional adverse association between diabetes and depression. The odds for experiencing depressive symptoms in diabetic patients are two times more than nondiabetic persons, and depression is an independent predictor for the onset of diabetes. However, depression has been approximately unrecognized and untreated in two-thirds of diabetic patients, which may lead to worsened diabetes complications. A cornerstone strategy for managing depression among diabetic patients is the use of diet to impro… Show more

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Cited by 6 publications
(5 citation statements)
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“…18 Dietary recommendations for depression are the same for chronic NCDs. 19 Personal counselling sessions and medications to manage depression (if required) could improve PA levels in these diabetic patients.…”
Section: Discussionmentioning
confidence: 99%
“…18 Dietary recommendations for depression are the same for chronic NCDs. 19 Personal counselling sessions and medications to manage depression (if required) could improve PA levels in these diabetic patients.…”
Section: Discussionmentioning
confidence: 99%
“…Many unpredictable effects such as changes in nutritional behaviour over time, which are difficult to control for, bias results even in carefully designed studies [ 25 ]. The nutritional effect of carbohydrates and protein on mood has been discussed for some time [ 26 - 28 ]. A high-fat diet is supposed to have a protective effect on chronic stress exposure in mice [ 29 ].…”
Section: Discussionmentioning
confidence: 99%
“…The changes described may be related to increased intake of omega-3 unsaturated fatty acids and possibly also by mediating levels of brainderived neurotrophic factor (BDNF), a neurotrophin implicated in depressive disorder. Patients with pre-existing metabolic and cardiovascular comorbidities have been shown to have inverse relationships with depressive symptoms and adherence to a Mediterranean diet that correlate with increases in serum BDNF [19,20]. While the sample sizes in these studies are small, it is reasonable to recommend consumption of a Mediterranean diet as an adjunct treatment for depressive symptoms and general mood disorders.…”
Section: Mediterranean Dietmentioning
confidence: 99%
“…Patients with depression showed changes in white matter integrity after six weeks of high-dose supplementation with omega-3 fatty acids [26], and one meta-analysis demonstrated inverse associations between depressive symptoms and omega-3 fatty acid intake in patients with diabetes [20]. A small RCT in elderly patients demonstrated improved geriatric depression scale scores (GDS) in patients with depression and cognitive decline after supplementation with omega-3 fatty acids [27], and several studies on patients with either major depressive disorder or depressive symptoms have suggested an association between omega-3 fatty acid supplementation and clinical improvement in depressive symptoms.…”
Section: Omega-3 Fatty Acidsmentioning
confidence: 99%