“…A formulation containing 15 g protein and 30-45 g carbohydrate/day, gave nitrogen balance, only moderate ketosis, normal serum electrolytes and uric acid. Low calorie semi-synthetic diets were advocated as a safer and more acceptable form of weight reduction than complete starvation (2). The present study was designed to determine the feasibility of a short period of inpatient management on a low calorie semi-synthetic diet and then follow-up at weekly intervals.…”