Dietary Therapies in Pediatric Inflammatory Bowel Disease

Lane, Erin R.; Lee, Dale; Suskind, David L.

doi:10.1016/j.gtc.2017.08.012

Cited by 19 publications

(13 citation statements)

References 98 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…One of the most studied exclusion diets is the specific carbohydrate diet (SCD). This diet removes all grains, sweeteners (except for honey), processed food, and all milk products except for hard cheeses and yogurt fermented longer than 24 h. Both clinical and laboratory improvement have been reported in pediatric and adult patients with IBD [49,50,51,52]. One study over 12 weeks in children and adolescents used capsule endoscopy and demonstrated mucosal healing [53].…”

Section: Scientific Basis Of Dietary Therapy For Ibdmentioning

confidence: 99%

“…One study over 12 weeks in children and adolescents used capsule endoscopy and demonstrated mucosal healing [53]. Therapy with the SCD has been shown to result in significant changes in microbial composition [49]. The SCD has been the best-studied food-based diet for IBD, and one survey with 417 respondents found patients reported significant improvement in symptoms, but that only 17% of patients partnered with a healthcare professional in the implementation of the SCD [50].…”

Section: Scientific Basis Of Dietary Therapy For Ibdmentioning

confidence: 99%

See 1 more Smart Citation

A Review of Dietary Therapy for IBD and a Vision for the Future

et al. 2019

Self Cite

View full text Add to dashboard Cite

Inflammatory bowel disease (IBD) is a chronic inflammatory condition affecting the gastrointestinal tract. The rising incidence of IBD has been associated with urbanization and shifts toward a Westernized diet. The intestinal microbiome has been a focus of disease pathogenesis and also therapeutic intervention. Dietary therapy for IBD has been well-studied with exclusive enteral nutrition, a formula-based diet with the exclusion of foods. In addition, interest in food-based exclusion diets has been increasing, with patients and families leading the charge. Challenges with dietary therapy for IBD include the lack of understanding of a detailed mechanistic pathway to explain the impact of diet on IBD pathogenesis and the difficult nature of designing and implementing dietary clinical trials. Epidemiological studies have demonstrated associations and intervention studies have demonstrated efficacy, but specific dietary targets remain as hypotheses at present. Current IBD therapy focuses on suppression of the immune system, yet the incomplete efficacy of present drugs suggests that other therapies must be developed and employed. Dietary interventions, with known ability to modulate the intestinal microbiome, are a unique opportunity to improve outcomes in IBD. Dietary intervention trials are challenging, and capturing both broad dietary patterns as well as exposure to individual food compounds is important. With increasing patient interest and preliminary research in dietary therapy indicating efficacy, it is imperative to further advance the science of utilizing diet in IBD, as well as to support patients by proactively addressing diet within their care plan.

show abstract

Section: Scientific Basis Of Dietary Therapy For Ibdmentioning

confidence: 99%

Section: Scientific Basis Of Dietary Therapy For Ibdmentioning

confidence: 99%

A Review of Dietary Therapy for IBD and a Vision for the Future

et al. 2019

Self Cite

View full text Add to dashboard Cite

show abstract

“…Patients with strictures continue the quantitative restriction of fruits and vegetables on an individual basis. Positive results are especially recorded in children and young adults [121][122][123][124][125][126].…”

Section: Crohn's Disease Exclusion Diet (Cded)mentioning

confidence: 99%

The Modification of the Gut Microbiota via Selected Specific Diets in Patients with Crohn’s Disease

et al. 2021

View full text Add to dashboard Cite

Gastrointestinal symptoms in Crohn’s disease (CD) are common and affect the quality of life of patients; consequently, a growing number of studies have been published on diet interventions in this group. The role of the gut microbiota in the pathogenesis and the progression of inflammatory bowel diseases (IBD), including CD, has been widely discussed. Mainly, a decreased abundance of Firmicutes, species of the Bifidobacterium genus, and the Faecalibacterium prausnitzii species as well as a reduced general diversity have been described. In this review article, we summarize available data on the influence of reduction diets on the microbiome of patients with CD. One of the most frequently used elimination diets in CD patients is the low-FODMAP (Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols) diet. Although many papers show it may reduce abdominal pain, diarrhea, or bloating, it also reduces the intake of prebiotic substances, which can negatively affect the gut microbiota composition, decreasing the abundance of Bifidobacterium species and Faecalibacterium prausnitzii. Other elimination diets used by IBD patients, such as lactose-free or gluten-free diets, have also been shown to disturb the microbial diversity. On the other hand, CDED (Crohn’s disease exclusion diet) with partial enteral nutrition not only induces the remission of CD but also has a positive influence on the microbiota. The impact of diet interventions on the microbiota and, potentially, on the future course of the disease should be considered when nutritional guidelines for IBD patients are designed. Dietetic recommendations should be based not only on the regulation of the symptoms but also on the long-term development of the disease.

show abstract

“…Since the Western diets have risk characteristics for the development of IBD, we can assume that diets which exclude or restrict certain types of food, such as CDED or semi-vegetarian diets, can help reduce symptoms and prolong remission, although more studies are necessary to validate their use. 3,[27][28][29]…”

Section: Crohn's Disease Exclusion Dietmentioning

confidence: 99%

“…Dietary therapies that involve enteral nutrition (EN), modification of carbohydrates, and dietary fibers have been discussed and prescribed in the pediatric field as therapeutic and preventive proposals for Crohn's Disease (CD) and ulcerative colitis (UC) inflammatory episodes. 3 Thus, a critical bibliographical survey on the existing dietary treatments and their outcomes is necessary to guide the health professional in their therapeutic choice.…”

Section: Introductionmentioning

confidence: 99%

Oral and Enteral Nutrition Therapy in Inflammatory Bowel Diseases Among the Pediatric Population: A Literature Review

Souza

Draghi

Yonamine

2020

Rev. paul. pediatr.

View full text Add to dashboard Cite

ABSTRACT Objectives: To review the literature on oral and enteral nutrition therapy and investigate the evidence of its efficacy as a treatment, as well as in preventing relapses and reducing symptoms of inflammatory bowel diseases in the pediatric population. Data source: We performed a bibliographic search in the PubMed, Web of Science, and Latin American and Caribbean Health Sciences Literature (Literatura Latino-Americana e do Caribe em Ciências da Saúde - Lilacs) databases, using the keywords “inflammatory bowel disease,” “diet,” and “diet therapy” in English and Portuguese, with filters for pediatric studies published in the previous five years. Data summary: We selected 16 articles for this study, nine on exclusive and/or partial enteral nutrition and seven on modified oral diets, such as the specific carbohydrate diet (SCD) and the Crohn’s Disease exclusion diet (CDED). The studies found evaluated the anthropometric profile of patients and the inflammatory profile of diseases in children before and after the introduction of each specific nutrition therapy. All interventions presented positive changes in these parameters; however, the results were inconclusive regarding the efficacy of SCD and CDED in the treatment and prevention of relapses. Conclusions: Exclusive enteral nutrition has proven to be effective in inducing remission of Crohn’s Disease, and the use of partial enteral nutrition for maintenance treatment has shown promising results. Other modified oral diets are inconclusive concerning their effectiveness, requiring further randomized controlled clinical trials.

show abstract

Dietary Therapies in Pediatric Inflammatory Bowel Disease

Cited by 19 publications

References 98 publications

A Review of Dietary Therapy for IBD and a Vision for the Future

A Review of Dietary Therapy for IBD and a Vision for the Future

The Modification of the Gut Microbiota via Selected Specific Diets in Patients with Crohn’s Disease

Oral and Enteral Nutrition Therapy in Inflammatory Bowel Diseases Among the Pediatric Population: A Literature Review

Contact Info

Product

Resources

About