Dietary Taraxacum mongolicum polysaccharide ameliorates the growth, immune response, and antioxidant status in association with NF-κB, Nrf2 and TOR in Jian carp (Cyprinus carpio var. Jian)

Yu, Zhe; Zhao, Lei; Zhao, Jun-Liang; Xu, Wei; Guo, Ze-hao; Zhang, Aizhong; Li, Muyang

doi:10.1016/j.aquaculture.2021.737522

Cited by 68 publications

(32 citation statements)

References 94 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Correspondingly, sod and gpx gene expression was also enhanced by 400 mg/kg AMP. Similarly, polysaccharide additives can enhance antioxidant defense in carp and tilapia by activating the Nrf2 signaling pathway [ 50 , 51 ]. However, the Nrf2 decreased in fish fed a diet supplemented with 4000 and 8000 mg/kg AMP, accompanied with a decrease in sod and gpx gene expression compared to 400 mg/kg AMP supplementation group.…”

Section: Discussionmentioning

confidence: 99%

Tolerance Assessment of Atractylodes macrocephala Polysaccharide in the Diet of Largemouth Bass (Micropterus salmoides)

Dong

Chen

et al. 2022

Antioxidants

View full text Add to dashboard Cite

Atractylodes macrocephala polysaccharide (AMP) can enhance antioxidant defense and anti-inflammation, as the tolerance levels of AMP in aquaculture is important for additive utilization. However, the tolerance dose of AMP is unknown. We assess the tolerance levels of AMP in juvenile largemouth bass (3.38 ± 0.11 g) by feeding them a 0, 400, 4000, or 8000 mg/kg AMP supplemented diet for 10 weeks. The 400 mg/kg AMP dose increased growth performance. The Nrf2/Keap1 signaling pathway was activated, as indicated by Keap1 and Nrf2 protein levels in the liver. Enhanced activity of antioxidant enzymes (SOD, GPx), together with increased mRNA levels of antioxidant genes (sod, gpx) and decreased accumulation of reactive oxygen species (ROS) and MDA, was found in the liver, implying the antioxidant effect of AMP. Nutrient absorption was enhanced by AMP, as reflected by the increased length of intestinal villi and microvilli. However, 4000 and 8000 mg/kg AMP induced oxidant stress, as indicated by increased plasma ALT and AST content and decreased mRNA levels of antioxidant genes (sod, gpx) in the liver and intestinal tissues. Inflammatory reactions were also induced by high doses of AMP, as reflected by enhanced levels of pro-inflammatory cytokines (tnfα, nfκb) in the liver, intestinal, and kidney tissues and inhibited levels of anti-inflammatory cytokines (tgfβ, iκb). Histological analysis reveals inflammatory cell infiltration and tissue damage. Thus, the safe tolerance margin of AMP supplement for largemouth bass was 400–4000 mg/kg.

show abstract

Section: Discussionmentioning

confidence: 99%

Tolerance Assessment of Atractylodes macrocephala Polysaccharide in the Diet of Largemouth Bass (Micropterus salmoides)

Dong

Chen

et al. 2022

Antioxidants

View full text Add to dashboard Cite

show abstract

“…Recently, Zhao et al, (2022) reported that diets containing DPs improved the growth, antioxidant response and inhibits the inflammation in Channa asiatica after exposure to hexavalent chromium. Yu et al (2022b) demonstrated that dietary inclusion of DP improves the growth performance, digestive enzyme activity and immune response of Cyprinus carpio. To best of our knowledge, very few studies was conducted using DP in fish.…”

Section: Dandelion Polysaccharides (Dp)mentioning

confidence: 97%

Potential Role of Plant Polysaccharides as Immunostimulants in Aquaculture – A Review

Rajan

Dharmaraj

Mohan³

2023

Annals of Animal Science

View full text Add to dashboard Cite

Aquaculture is one of the primary food-producing sectors in the world that ensures human nourishment. However, aqua farmers are facing serious problems due to disease out breaks and development of antimicrobial resistance. Until now, chemical or antibiotic based strategies has been applied to control disease related concern in aquaculture. Frequent usage of antibiotics in feed or usage of disinfectant to overcome the disease may end up with negative impacts to the environment and human. Utilization of plant derived polysaccharides has been drastically increased due to their effective roles and could serve as a best replacement for chemical agents and antibiotics. In addition, plant derived compounds and plant extracts was utilized to improve the immunity, intestinal health and growth performance of aquaculturable organisms. In addition, large number of plant-based polysaccharides was utilized as immunostimulants in aquaculture. Hence, this review aims to highlight the multifunctional properties of plant-based polysaccharides in aquaculture. Moreover, advantages and different concentration of plant polysaccharides as a feed additives in aquaculture sector has been discussed herein.

show abstract

“…(2) Polysaccharides can retain water, promote peristalsis, encourage the feeling of satiety, and retard the rate of emptying [ 20 ], thus promoting the digestion and absorption of nutrients. (3) The reason why dietary plant-derived polysaccharides positively influence the activity of digestive enzymes may be attributed to their beneficial effects on beneficial bacteria in the intestinal tract and the intestinal morphology of poultry [ 64 ].…”

Section: Effects Of Plant-derived Polysaccharides On Intestinal Barri...mentioning

confidence: 99%

Progress of Studies on Plant-Derived Polysaccharides Affecting Intestinal Barrier Function in Poultry

Guo

Xing

et al. 2022

Animals

View full text Add to dashboard Cite

As natural bioactive components, plant-derived polysaccharides have many biological functions, such as anti-inflammatory, antioxidant, anticoccidial, and immunity regulation, and have been widely used in poultry production. In this review paper, firstly, the sources and structures of plant-derived polysaccharides are reviewed; secondly, the effects of plant-derived polysaccharides on the intestinal microbiome, permeability, morphology and immune function of poultry are summarized; thirdly, the potential molecular regulation mechanism of plant-derived polysaccharides on the intestinal barrier function of poultry was preliminarily analyzed. The review paper will bring a basis for the scientific utilization of plant-derived polysaccharides in the poultry industry.

show abstract

Dietary Taraxacum mongolicum polysaccharide ameliorates the growth, immune response, and antioxidant status in association with NF-κB, Nrf2 and TOR in Jian carp (Cyprinus carpio var. Jian)

Cited by 68 publications

References 94 publications

Tolerance Assessment of Atractylodes macrocephala Polysaccharide in the Diet of Largemouth Bass (Micropterus salmoides)

Tolerance Assessment of Atractylodes macrocephala Polysaccharide in the Diet of Largemouth Bass (Micropterus salmoides)

Potential Role of Plant Polysaccharides as Immunostimulants in Aquaculture – A Review

Progress of Studies on Plant-Derived Polysaccharides Affecting Intestinal Barrier Function in Poultry

Contact Info

Product

Resources

About