Nutritional Oncology 2006
DOI: 10.1016/b978-012088393-6/50084-1
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Dietary Supplements in Cancer Prevention and Therapy

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“…The gains made in in vitro investigations and the use of animal models for in vivo experimentation on the mechanisms of action of various phytochemicals and their bioavailability provide the foundation for pre-clinical and clinical trials. The paradigm of a rigorous systematic research approach to access the health benefits of nutraceuticals and their recommendation has been proposed by Dr. Mary Frances Picciano and colleagues (Table 1.2) (Picciano et al 2006). The paradigm begins with preclinical in vitro and in vivo studies and epidemiological evidence, before human clinical trials are conducted.…”
Section: Current Research and Future Directionsmentioning
confidence: 99%
“…The gains made in in vitro investigations and the use of animal models for in vivo experimentation on the mechanisms of action of various phytochemicals and their bioavailability provide the foundation for pre-clinical and clinical trials. The paradigm of a rigorous systematic research approach to access the health benefits of nutraceuticals and their recommendation has been proposed by Dr. Mary Frances Picciano and colleagues (Table 1.2) (Picciano et al 2006). The paradigm begins with preclinical in vitro and in vivo studies and epidemiological evidence, before human clinical trials are conducted.…”
Section: Current Research and Future Directionsmentioning
confidence: 99%