Dietary supplement for relieving menopausal symptoms in Egyptian perimenopausal women

Shebini, Salwa M. El; Fouad, Suzanne; Abdel-Moaty, Maha; Ahmed, Nihad H.; Hussein, Ahmed Mohamed Saied; Essa, Hend A.; Tapozada, Salwa T.

doi:10.1186/s42269-020-00291-2

Cited by 3 publications

(1 citation statement)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Therefore, post menopause, when they suffer from estrogen deficiency, phytoestrogen rich foods can be provided as supplements to improve the symptoms as well as quality of life. A study performed in Egypt on perimenopausal women, to analyze the efficiency of dietary supplements comprising peanut, sesame, coriander seeds and thyme, demonstrated the efficiency of the formulation in improving psychological, somatic and urogenital symptoms [30]. Dairy proteins have positive health implications in post-menopausal women.…”

Section: Functional Food For Post-menopausementioning

confidence: 99%

Proposed Design and In-silico Studies of Functional Idli as a Prophylactic Measure to Reduce Post-Menopausal Adverse Effects in Women

Mishra,

Vuppu

2023

Food Science and Engineering

View full text Add to dashboard Cite

Food Science and Engineering have become a rapidly evolving domain that has gained prominence in recent years to facilitate the development of enriched food products (like functional foods). It is utilized as a prophylactic measure for several health conditions like osteoporosis, obesity, cardiovascular diseases, and so on. Functional foods perform prophylactic activity through components like phytochemicals in their ingredients which may interact with the target receptors in susceptible people. The post-menopausal women become susceptible to numerous complications, including bone atrophy, osteoporosis, depression, dementia, obesity, vasomotor symptoms, and other lifestyle disorders. As reduced estrogen production is the major reason for such conditions' development, therapeutic interventions like hormone replacement therapy are administered to treat the complications associated with post-menopause. Hormone therapy is identified to be associated with some important limitations. This gives rise to the need to develop safer approaches for prophylaxis of post-menopausal adverse. In this review, we attempt to propose a design of functional idli made up of oats (Avena sativa), soybean (Glycine max), decorticated black gram (Vigna mungo), rice (Oryza sativa), moringa leaves (Moringa oleifera), spinach (Spinacia oleraceae) and fenugreek (Trigonella foenum-graceum) as a prophylactic measure to reduce post-menopausal adverse effects in women. These ingredients are sources of phytoestrogen (that structurally mimics human estrogen), consumption of which is beneficial in promoting healthy life in post-menopausal women. Computational studies like molecular docking can be utilized for in-silico validation of the efficacy of the formulation by demonstrating the effective binding of the phytoestrogens with the estrogen receptors α and β.

show abstract

Section: Functional Food For Post-menopausementioning

confidence: 99%

Proposed Design and In-silico Studies of Functional Idli as a Prophylactic Measure to Reduce Post-Menopausal Adverse Effects in Women

Mishra,

Vuppu

2023

Food Science and Engineering

View full text Add to dashboard Cite

show abstract

The effects of life style modification versus food supplementation on menopausal symptoms

et al. 2021

View full text Add to dashboard Cite

Background Nutrition and good health are two dependent parallel axes; female’s health at different ages in general and at the time of menopause in particular has received a lot of attention last several years. The objective of this experimental study was to evaluate the effect of consuming food supplement versus lifestyle modification in the dietary habit on menopausal symptoms in perimenopausal Egyptians females. Results Forty seven females in the perimenopausal stage of life with mean age 46.04 ± 5.88 years participated on the food supplement consumption group, they consumed 75 g per day of a rusk (prepared from corn flour, wheat flour 72%, full cream milk powder, flaxseed oil, wheat germ, clove and cinnamon powder) for 2 months. They were compared with the control group (forty nine females with mean age 46.91 ± 5.39 years) who changed their foods habits to a healthy life style. Menopause rating scale and the biochemical analysis were comparable on day 1 and on day 60. The total menopause rating scale and its three subscales (psychological, urogenital and somatic), waist circumference, serum follicle stimulating hormone and estradiol in the corn rusk supplement group showed a statistically significant improvement. No significant difference was noted in the control group apart of the psychological subscale and waist circumference. Conclusions Corn Rusk enriched with clove and cinnamon as a food supplement snake is promising to relief menopausal symptoms and should be considered on the diet of menopausal females.

show abstract

Impact of Cumulative Exposure to Circulating Ovarian Sex Hormones on Increasing the Risk of Hormone Receptor-Positive Breast Cancer

Mohanty,

Panda

et al. 2024

J Bio-X Res

View full text Add to dashboard Cite

There were 2.3 million new cases of breast cancer registered in 2020, establishing it as the world’s leading cancer. The regular exposure of breast cells to circulating ovarian sex hormones may contribute to cancer growth at all stages. A literature review was performed by downloading research articles from PubMed Central, with keywords such as breast cancer, hormone exposure in breast cancer, estrogen/progesterone exposure in breast cancer, and breast cancer risk factors. Since breast cancer is a hormone-related disease, several factors that influence hormonal conditions or are indicators of alterations in hormonal conditions have been linked with the risk for breast cancer. Likewise, an elevated risk for breast cancer has been related to reproductive history and exogenous estrogen exposure because they may amplify lifetime estrogen exposure. All these factors address the total cumulative exposure to circulating ovarian sex hormones that a female is vulnerable to in her lifetime. A healthy lifestyle, a more extended breastfeeding period, and regular physical activity may help lower one’s risk. This review summarizes the factors that increase the risk of estrogen/progesterone (hormone receptor) receptor-positive breast cancer due to overall cumulative estrogen exposure, with an understanding of estrogen biosynthesis mechanisms and estrogen receptor signaling.

show abstract

Dietary supplement for relieving menopausal symptoms in Egyptian perimenopausal women

Cited by 3 publications

References 26 publications

Proposed Design and In-silico Studies of Functional Idli as a Prophylactic Measure to Reduce Post-Menopausal Adverse Effects in Women

Proposed Design and In-silico Studies of Functional Idli as a Prophylactic Measure to Reduce Post-Menopausal Adverse Effects in Women

The effects of life style modification versus food supplementation on menopausal symptoms

Impact of Cumulative Exposure to Circulating Ovarian Sex Hormones on Increasing the Risk of Hormone Receptor-Positive Breast Cancer

Contact Info

Product

Resources

About