Dietary sodium restriction in the prophylaxis of hypertensive disorders of pregnancy: effects on the intake of other nutrients

Abstract

Dietary sodium restriction is used in the Neth erlands in the prophylaxis of preeclampsia. To study the effects of long-term sodium restriction on the intake of other nutrients and the outcome of pregnancy, 6 8 healthy nulliparous pregnant women were randomly assigned to either a low-sodium diet (20 mmol/24 h) or an unrestricted diet. The diet was consumed between week 14 of gestation and delivery. The dietary intakes of energy, fat, protein, carbohydrate, sodium, potassium, and calcium were esti mated with the dietary-history technique. A low-sodium diet re duced the intake of protein (by «=15 g/24 h), fat (by 20 g/24 h), and calcium (by 350 mg/24 h) and tended to decrease the energy intake (by ^O.? MJ/24 h). The intakes of carbohydrate and potassium did not differ between the groups. The maternal weight gain was less in the low-sodium group (6.0 ± 3 .7 compared with 11.7 ± 4.7 kg). Mean birth weight was not significantly different (3.2 ± 0.5 compared with 3.4 ± 0.5 kg).Am J Clin Nutv 1995;62:49-57.KEY WORDS Sodium-restricted diet, pregnancy, prophy laxis of preeclampsia, energy intake, fat intake, protein intake, carbohydrate intake, calcium intake, maternal weight gain, birth weight, body fat mass

Intrauterine growth restriction in rats is associated with hypertension and renal dysfunction in adulthood

“…Hence, we wanted to characterize the outcome of rat offspring born from dams on low-sodium diet. However, many studies have shown that dietary sodium restriction in humans does not reduce gestational hypertension (14,47). Our findings in the rat would support the latter statement.…”

First Trimester Dietary Intake, Biochemical Measures, and Subsequent Gestational Hypertension Among Nulliparous Women

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Differentiation of HELLP patients from healthy pregnant women by proteome analysis—On the way towards a clinical marker set☆

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