Dietary self-selection in chronically insulin-treated golden hamsters.

DiBattista, David; Helm, K. Jennifer

doi:10.1037/0735-7044.100.1.129

Cited by 3 publications

(4 citation statements)

References 11 publications

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“…It is not known if the opposite parametric relationship is true for the involvement of the hippocampus in EBC. Previous studies examining the role of the hippocampus during trace EBC kept the CS duration the same (around 250 ms) and manipulated the duration of the trace interval (Kim, Clark, & Thompson, 1995; Moyer, Deyo, & Disterhoft, 1990; Port et al, 1986; Solomon et al, 1986; Weiss et al, 1999). …”

Section: Discussionmentioning

confidence: 99%

Differential effects of the cannabinoid agonist WIN55,212–2 on delay and trace eyeblink conditioning.

Steinmetz¹,

Freeman²

2013

Behavioral Neuroscience

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Central cannabinoid-1 receptors (CB1R) play a role in the acquisition of delay eyeblink conditioning but not trace eyeblink conditioning in humans and animals. However, it is not clear why trace conditioning is immune to the effects of cannabinoid receptor compounds. The current study examined the effects of variants of delay and trace conditioning procedures to elucidate the factors that determine the effects of CB1R agonists on eyeblink conditioning. In Experiment 1 rats were administered the cannabinoid agonist WIN55,212-2 during delay, long delay, or trace conditioning. Rats were impaired during delay and long delay but not trace conditioning; the impairment was greater for long delay than delay conditioning. Trace conditioning was further examined in Experiment 2 by manipulating the trace interval and keeping constant the conditioned stimulus (CS) duration. It was found that when the trace interval was 300 ms or less WIN55,212-2 administration impaired the rate of learning. Experiment 3 tested whether the trace interval duration or the relative durations of the CS and trace interval were critical parameters influencing the effects of WIN55,212-2 on eyeblink conditioning. Rats were not impaired with a 100 ms CS, 200 ms trace paradigm but were impaired with a 1000 ms CS, 500 ms trace paradigm, indicating that the duration of the trace interval does not matter but the proportion of the interstimulus interval occupied by the CS relative to the trace period is critical. Taken together the results indicate that cannabinoid agonists affect cerebellar learning the CS is longer than the trace interval.

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Section: Discussionmentioning

confidence: 99%

Differential effects of the cannabinoid agonist WIN55,212–2 on delay and trace eyeblink conditioning.

Steinmetz¹,

Freeman²

2013

Behavioral Neuroscience

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“…Furthermore, the long-term food intake of Choice hamsters following deprivation was not limited simply by the mass of the ingested food, as hamsters on the more calorically dense Choice diet typically consumed only about half as many grams of food each day as did chow-fed hamsters. It thus remains unclear why hamsters do not become hyperphagic following deprivation, when they readily increase their intake in a variety of other circumstances (e.g., Browne & Borer, 1978; DiBattista & Helm, 1986; Fleming & Miceli, 1983; Rowland, 1984a; Silverman & Zucker, 1976).…”

Section: Discussionmentioning

confidence: 99%

“…, chronic exposure to cold (Rowland, 1984a), lactation (Fleming & Miceli, 1983), diabetes (Rowland & Caputo, 1985), and both acute and chronic insulin administration (DiBattista, 1984;DiBattista & Helm, 1986;Rowland, 1978). Thus the failure of hamsters to compensate for food deprivation and restriction by increasing their food consumption is not the result of a global inability to increase intake above normal levels.…”

mentioning

confidence: 99%

“…The basis for the failure of hamsters to increase food intake in response to either food deprivation or restriction is not obvious, as deprived hamsters demonstrate physiological changes similar to those seen in other species, including increases in circulating free fatty acids and ketones, decreased insulin levels, and rapid liver glycogen depletion (Borer et al, 1979; Rowland, 1982, 1984b). Furthermore, hamsters increase their food consumption under circumstances of dietary dilution (Silverman & Zucker, 1976), voluntary exercise (Browne & Borer, 1978), chronic exposure to cold (Rowland, 1984a), lactation (Fleming & Miceli, 1983), diabetes (Rowland & Caputo, 1985), and both acute and chronic insulin administration (DiBattista, 1984; DiBattista & Helm, 1986; Rowland, 1978). Thus the failure of hamsters to compensate for food deprivation and restriction by increasing their food consumption is not the result of a global inability to increase intake above normal levels.…”

mentioning

confidence: 99%

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Dietary self-selection of golden hamsters in response to acute food deprivation and chronic food restriction.

DiBattista¹

1987

Behavioral Neuroscience

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Adult male golden hamsters were maintained on either Purine Rat Chow (Chow diet) or a self-selection diet consisting of high-protein chow, pure fat, and pure carbohydrate (Choice diet). In Experiment 1, animals were deprived of food for single periods of up to 48 hr. Animals on the Chow diet did not increase intake at any time after deprivation; animals on the Choice diet selectively increased their consumption of fat-derived calories and increased their total caloric intake during the first 6 hr of refeeding, but not thereafter. The nature of the diet did not influence the rate at which animals regained weight following deprivation. In Experiment 2, hamsters were placed on food-restriction schedules (access to food either for 1 hr/day only or on alternate days only) until they lost 20% of starting body weight. Chow-fed animals demonstrated little or no change in food intake either during or after food restriction. Hamsters on the Choice diet consumed more calories and lost weight more slowly than did chow-fed animals during 1-hr/day feeding; intake of fat-derived calories was elevated during restriction. Choice hamsters increased total caloric intake only towards the end of the alternate-days restriction schedule. Choice hamsters were hyperphagic following both types of food-restriction schedules, but no increased preference for fat-derived calories was observed. Factors influencing food consumption of hamsters in response to deprivation and restriction are discussed.

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Dietary protein restriction and selective preference for a protein-containing diet in the golden hamster (Mesocricetus auratus)

DiBattista

Campbell

1998

Physiology & Behavior

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Dietary self-selection in chronically insulin-treated golden hamsters.

Cited by 3 publications

References 11 publications

Differential effects of the cannabinoid agonist WIN55,212–2 on delay and trace eyeblink conditioning.

Differential effects of the cannabinoid agonist WIN55,212–2 on delay and trace eyeblink conditioning.

Dietary self-selection of golden hamsters in response to acute food deprivation and chronic food restriction.

Dietary protein restriction and selective preference for a protein-containing diet in the golden hamster (Mesocricetus auratus)

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