2008
DOI: 10.1016/j.atherosclerosis.2007.12.034
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Dietary salt restriction increases plasma lipoprotein and inflammatory marker concentrations in hypertensive patients

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Cited by 40 publications
(31 citation statements)
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“…The results of our study are in line with those of an intervention study by Nakandakare et al (22) who studied the effects of 1 wk of consumption of a control diet (160 mmol Na/d) followed by 3 wk of low sodium intake (60 mmol Na/d). Nonpharmacologically treated hypertensive adult patients were included in the study, whereas subjects with severe hypertriglyceridemia, obesity, diabetes, alcohol abuse, and the use of any drug that could interfere with lipid metabolism were excluded.…”
Section: Discussionsupporting
confidence: 93%
See 1 more Smart Citation
“…The results of our study are in line with those of an intervention study by Nakandakare et al (22) who studied the effects of 1 wk of consumption of a control diet (160 mmol Na/d) followed by 3 wk of low sodium intake (60 mmol Na/d). Nonpharmacologically treated hypertensive adult patients were included in the study, whereas subjects with severe hypertriglyceridemia, obesity, diabetes, alcohol abuse, and the use of any drug that could interfere with lipid metabolism were excluded.…”
Section: Discussionsupporting
confidence: 93%
“…An intervention study showed that a reduction of sodium intake was accompanied by an increase in hsCRP (22). In contrast, a cross-sectional study showed that higher amounts of 24-h sodium excretion were associated with increased concentrations of serum hsCRP (23).…”
Section: Introductionmentioning
confidence: 83%
“…Severe salt restriction (20 to 60 mmol sodium/day) has been associated with higher cholesterol levels (37,38); however, moderate salt restriction of 85 mmol sodium/ day does not modify lipid concentration (37). The present study showed a modest increase of cholesterol levels after prolonged high salt intake.…”
Section: Discussionsupporting
confidence: 49%
“…Por outro lado, também tem sido evidenciado que a restrição alimentar crônica de cloreto de sódio, frequentemente, encontra-se associada a efeitos adversos como: diminuição da sensibilidade à insulina (AMES, 2001;FLISER et al, 1995;GARG et al, 2011;TOWNSEND et al, 2007), aumento na atividade dos sistemas nervoso simpático (TADDEI et al, 1995;BROOKS et al, 2001) e renina-angiotensina IVANOVSKI et al, 2005), além de hiperlipidemia (GRAUDAL et al, 2012;CATANOZI et al, 2001CATANOZI et al, e 2003NAKANDAKARE et al, 2008;RUPPERT et al, 1994).…”
Section: Sódio Alimentar E Risco De Doença Cardiovascularunclassified
“…No presente estudo, o aumento da colesterolemia e da trigliceridemia nos grupos tratados com dieta hipossódica (N-NS vs N-HS e H-NS vs H-HS) corrobora os resultados obtidos em estudos prévios do laboratório (CATANOZI et al, 2001;NAKANDAKARE et al, 2008), nos quais foram observados hiperlipidemia decorrente de menor remoção plasmática VLDL após restrição de NaCl (CATANOZI et al, 2001 (CHAI et al, 2010). Estudos em humanos confirmaram esta relação, demonstrando que a ANG II diminui o fluxo sanguíneo microvascular à musculatura esquelética e que este efeito é revertido com a administração de bloqueador do receptor AT1 (GOOSSENS et al, 2004;SAUDER et al, 2012).…”
Section: )unclassified