Dietary ractopamine supplementation during the first lactation affects milk composition, piglet growth and sow reproductive performance

Wettere, W. H. E. J. van; Pain, S. J.; Hughes, Paul E.

doi:10.1016/j.anireprosci.2016.09.009

Cited by 4 publications

(2 citation statements)

References 22 publications

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“…Ractopamine (RAC) is an artificially synthesized β-adrenergic agonist, which was originally used as a bronchial dilating agent for the treatment of pulmonary disease and asthma [ 1 , 2 ]. However, in the farming industry, RAC is also illegally applied as a nutrient repartitioning agent to increase muscle and reduce fat accumulation [ 3 , 4 , 5 ]. It has been proven that RAC can be retained in animals and subsequently enters the human body through the food chain, causing cumulative toxicity.…”

Section: Introductionmentioning

confidence: 99%

Reproducible Molecularly Imprinted Piezoelectric Sensor for Accurate and Sensitive Detection of Ractopamine in Swine and Feed Products

Pan

et al. 2018

Sensors

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This paper describes the development of a reproducible molecularly imprinted piezoelectric sensor for the accurate and sensitive detection of ractopamine (RAC) in swine and feed products. The synthesized molecularly imprinted polymer (MIP) was directly immobilized on the surface of a quartz crystal microbalance (QCM) Au chip as the recognition element. The experimental parameters in the fabrication, measurement and regeneration process were evaluated in detail to produce an MIP-based piezoelectric sensor with high sensing capability. The developed piezoelectric sensor was verified to perform favorably in the RAC analysis of swine and feed products, with acceptable accuracy (recovery: 75.9–93.3%), precision [relative standard deviation (n = 3): 2.3–6.4%], and sensitivity [limit of detection: 0.46 ng g−1 (swine) and 0.38 ng g−1 (feed)]. This portable MIP-based chip for the piezoelectric sensing of RAC could be reused for at least 30 cycles and easily stored for a long time. These results demonstrated that the developed MIP-based piezoelectric sensor presents an accurate, sensitive and cost-effective method for the quantitative detection of RAC in complex samples. This research offers a promising strategy for the development of novel effective devices used for use in food safety analysis.

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Section: Introductionmentioning

confidence: 99%

Reproducible Molecularly Imprinted Piezoelectric Sensor for Accurate and Sensitive Detection of Ractopamine in Swine and Feed Products

Pan

et al. 2018

Sensors

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“…........................................................................... 42 Gráfico 4 -Avaliação do efeito de tempo sobre peso e ganho diário de peso dos leitões até o desmame ................................................................................................................................... 46 Gráfico 5 -Avaliação do efeito da suplementação de ractopamina sobre a quantidade de Plaquetas durante o período de gestação e lactação ................................................................. 48 Gráfico 6 -Avaliação do efeito de tempo sobre os valores de hemograma das fêmeas .......... 49 Gráfico 7 Avaliação do efeito de tempo sobre os valores da bioquímica sanguínea das fêmeas52 Gráfico 8 -Avaliação do efeito da suplementação de ractopamina sobre os valores de linfócitos durante o período de gestação e lactação ................................................................. 54 Gráfico 9 -Avaliação do efeito de tempo sobre os valores de leucócitos, neutrófilos e basófilos das fêmeas ................................................................................................................. 54 Gráfico 10 -Avaliação de concentração de hemoglobina corpuscular media e hematócrito de leitões nascidos de fêmeas suplementadas com ractopamina durante a gestação .................... 56 Gráfico 11 Avaliação do efeito de tempo sobre os valores de volume corpuscular médio, hemoglobina corpuscular média, plaquetas e hemoglobina dos leitões até o desmame .......... 56 Gráfico 12 -Avaliação do efeito de tempo sobre os valores de bioquímica sanguínea dos leitões até o desmame ............................................................................................................... 58 Gráfico 13 Avaliação do efeito de tempo sobre os valores de leucócitos, neutrófilos e linfócitos de leitões até o desmame .......................................................................................... 59 Gráfico 14 Avaliação do efeito de tempo sobre os valores de leucócitos, neutrófilos e linfócitos de leitões até o desmame .......................................................................................... 60 AGOSTINISMITH;PAULSON, 1994). O aumento no fluxo de nutrientes em nível placentário e tecidual apresenta impactos positivos na condição corporal da fêmea gestante e no desenvolvimento do feto(DALLANORA et al, 2017), o que pode garantir uma maior taxa de crescimento dos leitões e produção de leite(WETTERE et al, 2016).…”

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<b>Adição de ractopamina à nutrição de fêmeas suínas gestantes:</b> quais os impactos sobre o neonato?

Garcia¹

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pode estar relacionado a um aumento numérico do peso ao nascimento dos leitões. Contudo, a suplementação de Rac durante os 25 -50 dias da gestação não influencia negativamente no desempenho produtivo das fêmeas e sua progênie até o desmame. Palavras-chave: Ractopamina. Gestação. Fibra muscular. Suínos. Progênie. ABSTRACT MARTINEZ, C. H. G., Ractopamine addition to the nutrition of pregnant sows: What are the impacts on the neonate? [Adição de ractopamina à nutrição de fêmeas suínas gestantes: Quais os impactos sobre o neonato?] 2018. 76f. Dissertação (Mestrado em Ciências) -Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, 2108.The ractopamine (Rac) has been used in pregnant sows, aiming to improve the nutritional contribution to the fetus, being considered as nutrient delivery, promoting lipolysis and retention of nitrogen and protein synthesis. Increased nutrient flow may have positive impacts on the body condition of sows and fetal development. The present study evaluated the effects of the inclusion of 10 and 20 mg / kg of ractopamine in the diet sows from 25 to 50 days of pregnancy. Assessing possible effects on productive, reproductive performance, physiological parameters, complete blood count and blood serum biochemistry of females and on vitality, complete blood count, blood serum biochemistry, number of muscle fibers in the semitendinosus muscle and metabolic status of their piglets. Forty one sows of hybrid commercial line, DB 90 (DB-Genetics Swine, Patos de Minas, Minas Gerais),were used and divided according to the order of parity in 3 treatments: Control: No ractopamine; Rac10: 10 mg / kg ractopamine; Rac20: 20 mg / kg ractopamine. The treatment was administered daily via top dressed during the 25 to 50 days of gestation. The evaluations and sample collections were performed at 25, 37, 50, 107 days of gestation and at 1, 7, 14 and 21 days of lactation.Assessment of vitality was used the apgar score test modified by Motta-Rojas (2005). The supplementation of ractopamine during gestation did not influence the female reproductive performance, piglets performance until weaning and muscle fibers in the semitendinosus muscle at birth. There was an increase in heart rate and low vitality in females supplemented with Rac. There were alterations in the complete blood count, blood serum biochemistry of the females, but not in the piglets. The results obtained from the hemogram and blood biochemistry analysis indicate the action of ractopamine on the lipid and protein metabolism of the females without significant reflexes in the piglets values. The present study concluded that the supplementation of Rac during the 25 to 50 days of gestation does not negatively influence the metabolism of the females and their progeny until weaning. On the other hand, supplementation of Rac increases the heart rate without increasing respiratory rate and rectal temperature of the females, however, this can still be considered within the normal physiological parameters during gestation. The inc...

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Feeding the modern sow to sustain high productivity

Theil

Krogh

Bruun

et al. 2022

Molecular Reproduction Devel

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Selection for hyper-prolific sows has increased the litter size by more than 50% during the last three decades, and proper nutrition of the female pigs has concomitantly changed due to improved prolificacy and productivity of gilts and sows. This review summarizes the physiological characteristics and nutritional challenges associated with feeding modern hyper-prolific sows during the gilt rearing period and during gestation, transition, and lactation periods. The review presents up-to-date knowledge of the energy and lysine requirements of female pigs and focuses on how nutrition may increase fat gain and limit protein and weight gain in the gilt rearing period and in early and mid-gestation. In late gestation, fetal and mammary growth should be considered and during the transition, colostrum yield and farrowing performance need to be optimized.Finally, milk production should be optimized and body mobilization should be minimized in the lactation period to achieve high feed efficiency in hyperprolific sows.

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Dietary ractopamine supplementation during the first lactation affects milk composition, piglet growth and sow reproductive performance

Cited by 4 publications

References 22 publications

Reproducible Molecularly Imprinted Piezoelectric Sensor for Accurate and Sensitive Detection of Ractopamine in Swine and Feed Products

Reproducible Molecularly Imprinted Piezoelectric Sensor for Accurate and Sensitive Detection of Ractopamine in Swine and Feed Products

<b>Adição de ractopamina à nutrição de fêmeas suínas gestantes:</b> quais os impactos sobre o neonato?

Feeding the modern sow to sustain high productivity

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