Abstract:Iron (Fe) deficiency is endemic worldwide. We have recently found that increasing dietary protein dose‐dependently improves Fe balance in rats. This change is associated with increased DMT1 transcript expression, a key regulator of intestinocyte Fe uptake. To confirm the Fe balance results, Fe absorption studies were performed in rats fed either a 20% (control) or 40% (high) protein diet for 1 wk. Rats on the 40% protein diet absorbed 30±9% of ingested Fe while those on the 20% protein diet absorbed 18±8% (p= … Show more
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