Dietary polyphenols as therapeutic agents to combat COVID-19

Sarfraz, Iqra; Rasul, Azhar; Adem, Şevki; Uçak, İlknur; Sarfraz, Ayesha; Bukhari, Shazia Anwer; Elfiky, Abdo A.

doi:10.1016/b978-0-323-95578-2.00016-9

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2023

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“…), which shows that at least one monomer of SARS-CoV-2 spike RBD is in its “up” state [ [26] , [27] , [28] ]. Due to its pivotal role in the infection process, several studies targeted S with small molecules in an attempt to prevent the infection by blocking S-ACE2 binding [ 29 , 30 ].…”

Section: Introductionmentioning

confidence: 99%

“…Sarfraz et al reviewed the studied polyphenol compounds that show potential therapeutic efficacy against SAR-CoV and SARS-CoV-2 proteins, including the spike protein. They reported Naringenin, Epigallocatechin gallate (EGCG), and Curcumin as potential interest for the SARS-CoV-2 spike [ 30 ]. Singh et al studied plant-based bioactive compounds as inhibitors of the spike using computational methods.…”

Section: Introductionmentioning

confidence: 99%

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