Dietary palygorskite-based antibacterial agent supplementation as an alternative to antibiotic improves growth performance, intestinal mucosal barrier function, and immunity in broiler chickens

Zha, Pingping; Chen, Yueping; Wang, Shiqi; Wang, Aiqin; Zhou, Yanmin

doi:10.1016/j.psj.2021.101640

Cited by 10 publications

(13 citation statements)

References 77 publications

(115 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore, secretory IgA (SIgA) in the intestinal tract represents the first defense line against the damage to the intestinal epithelium from luminal antigens (e.g., bacteria, viruses, toxins) (Corthésy, 2010). As previously summarized, PAL possesses immunoregulatory property, and the application of PAL would improve immune organ function and promote the antibody production (Zha et al, 2022). Dietary PAL supplementation has shown to increase the intestinal SIgA, IgM and IgG concentrations to enhance the immunity of ducks (Wang et al, 2019).…”

Section: Discussionmentioning

confidence: 99%

Effects of dietary palygorskite supplementation on the growth performance, oxidative status, immune function, intestinal barrier and cecal microbial community of broilers

Chen

Wang

et al. 2022

Front. Microbiol.

Self Cite

View full text Add to dashboard Cite

The present study aimed to investigate the effects of palygorskite (PAL) as an alternative to antibiotic on the growth performance, oxidative status, immune function, intestinal barrier and cecal microbial community of broilers. A total of 360 1-day-old male Ross-308 broilers were randomly allotted to three treatments with eight replicates. Broilers in the three groups were designated as follows: basal diet (CON group), basal diet+50 mg/kg chlorotetracycline (ANT group), and basal diet+ 10 g/kg PAL (PAL group). Supplementing PAL reduced feed to gain ratio in broilers during 22 to 42 days of age (P < 0.05), with its value being similar to that of the ANT group (P > 0.05). Broilers fed a PAL-supplemented diet exerted decreased contents of interferon-γ (IFN-γ) and interleukin-1β in serum, and the same reduction was found in jejunal IFN-γ level, when compared to the CON group (P < 0.05). Moreover, compared with the CON group, broilers after PAL treatment had a lower malondialdehyde content in jejunal mucosa (P < 0.05). Supplementing PAL elevated jejunal villus height (VH) and ratio of VH to crypt depth compared with the ANT group (P < 0.05). Cecal microbiota communities among the three groups were significant different, as demonstrated by distinct clusters from partial least squares discriminant analysis, although dietary treatments had no significant effects on the bacterial richness and diversity indices (P > 0.05). At genus level, the addition of PAL increased the relative abundance of norank_f__Barnesiellaceae and decreased that of unclassified_f__Oscillospiraceae in cecal digesta compared with those in the CON group (P < 0.05); the proportion of genus norank_f__Barnesiellaceae was increased by PAL treatment when compared with the ANT group (P < 0.05). Moreover, spearman's correlations showed that the modulation of cecal microflora composition by PAL supplementation was closely correlated with the promotion of growth performance (feed to gain ratio) and intestinal health-related (contents of malondialdehyde and IFN-γ, and VH value in jejunum) variables of broilers (P < 0.05). Taken together, dietary PAL could improve the growth performance, antioxidant capacity, and immune status, as well as intestinal barrier function in broilers, which might be partially associated with the alteration of cecal microbiota. Moreover, dietary PAL may be a promising alternative to antibiotic growth promoter for broilers.

show abstract

Section: Discussionmentioning

confidence: 99%

Effects of dietary palygorskite supplementation on the growth performance, oxidative status, immune function, intestinal barrier and cecal microbial community of broilers

Chen

Wang

et al. 2022

Front. Microbiol.

Self Cite

View full text Add to dashboard Cite

show abstract

“…Many herbal extracts can slow down the emptying of the gastrointestinal tract ( Manzanilla, 2004 ), stimulate the secretion of digestive juices (saliva, bile, mucus) ( Platel, 2004 ) and increase the activity of digestive enzymes ( Platel, 1996 ), G of the animals, which i/G of the animals, which is one of the possible reasons why HE leads to an increase in ADG and FCR in broilers. Many studies have confirmed that the addition of substances such as palygorskite-based antibacterial agent ( Zha et al. 2021 ) and cetylpyridinium-montmorillonite ( Ke et al.…”

Section: Discussionmentioning

confidence: 99%

Effects of honeycomb extract on the growth performance, carcass traits, immunity, antioxidant function and intestinal microorganisms of yellow bantam broilers

Song

Chen

et al. 2022

Poultry Science

View full text Add to dashboard Cite

“…The histological measurement was performed as reported previously ( Zha et al, 2022 ). In detail, the formalin-fixed small intestinal segments were dehydrated in ethanol series of increasing concentrations up to absolute, cleared in xylene, and embedded in paraffin wax prior to sectioning.…”

Section: Methodsmentioning

confidence: 99%

An evaluation of graded levels of beta-sitosterol supplementation on growth performance, antioxidant status, and intestinal permeability-related parameters and morphology in broiler chickens at an early age

et al. 2022

Self Cite

View full text Add to dashboard Cite

Dietary palygorskite-based antibacterial agent supplementation as an alternative to antibiotic improves growth performance, intestinal mucosal barrier function, and immunity in broiler chickens

Cited by 10 publications

References 77 publications

Effects of dietary palygorskite supplementation on the growth performance, oxidative status, immune function, intestinal barrier and cecal microbial community of broilers

Effects of dietary palygorskite supplementation on the growth performance, oxidative status, immune function, intestinal barrier and cecal microbial community of broilers

Effects of honeycomb extract on the growth performance, carcass traits, immunity, antioxidant function and intestinal microorganisms of yellow bantam broilers

An evaluation of graded levels of beta-sitosterol supplementation on growth performance, antioxidant status, and intestinal permeability-related parameters and morphology in broiler chickens at an early age

Contact Info

Product

Resources

About