Dietary Manipulations for Nonalcoholic Fatty Liver Disease (NAFLD)

Cheah, Mark; McCullough, Arthur J.; Goh, George Boon‐Bee

doi:10.1016/b978-0-12-813822-9.00005-9

Cited by 7 publications

(8 citation statements)

References 103 publications

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“…The health-promoting quality of meat depends on the saturated fatty acid (SFA) content. A high saturated fatty acid diet has long been implicated with an increased risk of cardiovascular disease [ 21 ]. Studies have shown that C12:0, C14:0, and C16:0 have atherogenic properties, while C14:0, C16:0, and C18:0 have thrombogenic properties [ 22 ].…”

Section: Resultsmentioning

confidence: 99%

“…PUFAs, as essential fatty acids, are only available through dietary consumption [ 21 ]. The highest content of LA, 8.70 g/100 g, was found in meat obtained from the Limousins.…”

Section: Resultsmentioning

confidence: 99%

“…Table 5 presents the content of selected fatty acids in the muscle tissue of Polish Holstein-Friesian, Limousin, and PHF × Limousin hybrids. Cheah et al [21] reported that MUFAs may be an ideal substitute for SFA, obviating the adverse effects of SFAs; therefore, the aim should be to increase their share in the diet. The first of the lipid components analyzed was vaccenic acid (C18:1 trans-11; TVA), responsible for the efficiency of tissues and organs.…”

Section: Resultsmentioning

confidence: 99%

“…Das [ 20 ] reported that the ability of eicosapentaenoic acid (EPA, C20:5 n-3) and docosahexaenoic acid (DHA, C22:6 n-3) to suppress the production of pro-inflammatory cytokines and induce their anti-inflammatory effects results indirectly from their ability to increase mRNA Peroxisome proliferator-activated receptor gamma and protein activity. Additionally, Cheah et al [ 21 ] reported that diets rich in monounsaturated fatty acids (MUFAs) have been shown to have favorable anti-inflammatory and cardiovascular benefits.…”

Section: Introductionmentioning

confidence: 99%

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Effect of Breed on the Level of the Nutritional and Health-Promoting Quality of Semimembranosus Muscle in Purebred and Crossbred Bulls

Solarczyk

Gołębiewski

Slósarz

et al. 2020

Animals

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Meat from commercial breed cattle are very often used to crossbreed with dairy breeds. The effect of heterosis is most evident when crossbreeds are genetically different from each other. Therefore, the aim of the study was to determine the influence of breed types on the nutritional and pro-health quality of beef. The experiment was conducted on 62 bulls from three breeds: Limousin, Polish Holstein-Friesian, and Polish Holstein-Friesian (PHF) × Limousin. During the fattening period, the animals were fed ad libitum using the same diet. Bulls were slaughtered at 21–23 months of age. The meat of PHF × Limousin hybrids was characterized by the lowest level of SFA and the highest content of n-3 PUFA fatty acids, carnosine, and α-tocopherol compared to the values obtained for the Polish Holstein-Friesian and Limousin breeds. In the case of PHF × Limousin hybrids, there was a 6% increase in n-3 PUFA, 21% in carnosine, and 66% in α-tocopherol compared to the Polish Holstein-Friesian breed. Commodity crossbreeding significantly improved the quality of beef analyzed in this study, resulting in similar or even better results than purebred cattle. This meant that beef from the hybrids with PHF was of the best nutritional and health-promoting quality.

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Section: Resultsmentioning

confidence: 99%

“…PUFAs, as essential fatty acids, are only available through dietary consumption [ 21 ]. The highest content of LA, 8.70 g/100 g, was found in meat obtained from the Limousins.…”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Effect of Breed on the Level of the Nutritional and Health-Promoting Quality of Semimembranosus Muscle in Purebred and Crossbred Bulls

Solarczyk

Gołębiewski

Slósarz

et al. 2020

Animals

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“…Non-alcoholic fatty liver disease is a common chronic disease wherein triglycerides accumulate excessively in the liver without alcohol abuse (29). Moreover, NAFLD is closely associated with diabetes and metabolic syndrome, which are both related to the pathophysiology of inflammation and insulin resistance (30,31). Dietary MUFAs have been reported to improve lipid profile through their anti-inflammatory characteristics (30,32).…”

Section: Discussionmentioning

confidence: 99%

Effects of oily fish and its fatty acid intake on non-alcoholic fatty liver disease development among South Korean adults

Tan

Shin

2022

Front. Nutr.

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BackgroundThe benefits of fish fatty acid intake for non-alcoholic fatty liver disease (NAFLD) are rarely reported, although a previous study assessed the relationship between oily fish consumption and the prevalence of NAFLD.AimsWe investigated whether oily fish and fish-based monounsaturated fatty acids, polyunsaturated fatty acids, and omega-3 fatty acids affect the development of NAFLD in South Korean adults.MethodsIn this large-scale cohort study, 44,139 participants of the Health Examinees study were selected for analysis after 5 years of follow-up. NAFLD is diagnosed with a non-invasive index, the fatty liver index. Using multivariable Cox proportional hazards models, adjusted for age, body mass index, total energy intake, education, physical activity, smoking status, and drinking (alcohol) status, we calculated the hazard ratios and 95% confidence intervals.ResultsFor men, NAFLD had no statistically significant associations with quartiles of total oily fish or its fatty acid intake. However, among women, an inverse association was observed (all p for trend <0.05). Regarding the standard deviation (SD) increment of total oily fish or its fatty acid intake by one, all fatty acids from oily fish showed inverse associations for NAFLD in both men and women. After stratified analyses, we found that drinking status and menopause status were independent risk factors for NAFLD. Oily fish or its fatty acid intake has the same benefit pattern on metabolic dysfunction-associated fatty liver disease as NAFLD.ConclusionOily fish and its fatty acid intake showed a preventative benefit for NAFLD and metabolic dysfunction-associated fatty liver disease, especially in South Korean women.

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