Dietary intake of saturated fat by food source and incident cardiovascular disease: the Multi-Ethnic Study of Atherosclerosis

Otto, Marcia C. de Oliveira; Mozaffarian, Dariush; Kromhout, Daan; Bertoni, Alain G.; Sibley, Christopher T.; Jacobs, David R.; Nettleton, Jennifer A.

doi:10.3945/ajcn.112.037770

Cited by 300 publications

(239 citation statements)

References 42 publications

Supporting

Mentioning

204

Contrasting

Unclassified

Order By: Relevance

“…5 Esta relación ha sido confirmada por estudios recientes que señalan que el consumo de productos lácteos está inversamente asociado con enfermedades cardiovasculares y posiblemente también con el incremento del IMC. 31 Es necesario destacar que la presente investigación sólo estudió la relación entre el IMC y el consumo de lácteos con azúcar añadida por lo que, si se analizaran lácteos más saludables que no contuvieran hidratos de carbono añadidos como azúcar, chocolate u otros, la relación podría aumentar.…”

Section: 29unclassified

Ingesta de bebidas azucaradas analcohólicas e índice de masa corporal en escolares chilenos

Araneda¹,

Bustos²,

Cerecera³

et al. 2015

Salud Publica Mex

View full text Add to dashboard Cite

Objective. To estimate the association between the intake of sugar-sweetened non-alcoholic beverages and body mass index (BMI) in Chilean school children. Materials and methods. Food consumption frequency data were analyzed for school children aged 6 to 18. The association between consumption of sugar-sweetened beverages and BMI was estimated by multivariate lineal regression models. Results. Sugar-sweetened beverages are consumed on a daily basis by 92% (95%CI:90-94) of subjects with daily intake medians of 424 mL (p25-p75:212-707). Every extra daily portion of sugar-sweetened beverages consumed by school children aged 6 to 13 is associated with 0.13 BMI z-scores (95%CI:0.04-0.2;p=0.01). Conclusions. School children consume sugarsweetened beverages daily with intake medians close to 0.5 L.There is an association between sugar-sweetened beverage consumption and higher BMI in Chilean school children.Key words: beverages; body mass index; children; adolescents; Chile E l consumo de azúcares agregados -es decir, los que son incorporados a los alimentos durante su elaboración pero que no pertenecen a éstos de manera natural-en países desarrollados representa 16% de las calorías consumidas al día y, de éstas, 40% proviene de bebidas azucaradas analcohólicas, incluidas las energéticas y las bebidas para deportistas.

show abstract

Section: 29unclassified

Ingesta de bebidas azucaradas analcohólicas e índice de masa corporal en escolares chilenos

Araneda¹,

Bustos²,

Cerecera³

et al. 2015

Salud Publica Mex

View full text Add to dashboard Cite

show abstract

“…However, the majority of studies in recent years suggest no adverse effects on surrogate markers of cardiovascular disease (CVD) or cardiovascular prognosis [18,32]. The milk and dairy products used in those studies are mostly from cow and have a lower fat content than those from ewe’s milk, and their lipid profile is different.…”

Section: Introductionmentioning

confidence: 99%

Effect of ewe’s (semi-skimmed and whole) and cow’s milk yogurt consumption on the lipid profile of control subjects: a crossover study

Olmedilla‐Alonso

Nova-Rebato

García-González³

et al. 2017

Food & Nutrition Research

View full text Add to dashboard Cite

Yogurt is the most widely consumed fermented milk product worldwide. Studies have mainly used milk and dairy products from cow, which have a lower fat content than those from ewe and a different lipid profile. This study investigated the effect on the lipid profile of control subjects of three different set yogurts: (a) semi-skimmed ewe´s milk yogurt (2.8% milk fat); (b) whole ewe´s milk yogurt (5.8 % milk fat); (c) cow´s milk yogurt (3 % milk fat). A randomized crossover study included 30 healthy adults (16 women) to consume 250 g/yogurt/day during three consecutive 5-weeks periods separated by 4-week washouts. Blood samples were collected at the start and end of each period for the analysis of serum cholesterol (total, HDL-, LDL-) and triglycerides. We found no differences in the serum concentrations of lipid and lipoprotein fractions of the volunteers after the intake of any of the three types of yogurts. When the volunteers were grouped into two risk groups of risk according to their total cholesterol/HDL cholesterol ratio, the same differences between the groups in terms of the cholesterol (HDL-, LDL-) and triglyceride responses at baseline and after yogurt intake were found, with no effects due to the different types of yogurts. Moreover, we performed compositional analysis of the yogurts including determination of protein, fat, minerals and fatty acids (FA). Contents in protein, calcium, magnesium, non-protein nitrogen and some FA (mainly short-chain-FA) were higher for ewe’s than for cow’s milk yogurt. n6-n3 ratio was lower in the ewe’s milk yogurt. In conclusion, yogurt intake, from ewe’s and cow’s milk, at levels of consumption compatible with a varied diet, neither decreases nor increases plasma lipoprotein cholesterol levels in apparently healthy individuals. As ewe’s milk yogurt has a high content of macro- and micronutrients, certain target populations could benefit from its consumption.

show abstract

“…A lower hazard ratio (HR) for CVD was reported for every 5 g/d (HR 0·79; 95 % CI 0·68, 0·92) or 5 % of energy from dairy SFA (HR 0·62; 95 % CI 0·47, 0·82), whereas the equivalent intake of SFA from meat sources was associated with greater HR for CVD (HR for +5 g/d and a +5 % of energy from meat sources of SFA: 1·26; 95 % CI 1·02, 1·54 and 1·48; 95 % CI 0·98, 2·23, respectively) (13) . Furthermore, the substitution of 2 % of energy from meat sources of SFA with energy from dairy SFA was associated with a 25 % lower CVD risk (HR 0·75; 95 % CI 0·63, 0·91), suggesting that dairy foods containing SFA attenuated the detrimental association of SFA with CVD mortality.…”

Section: )mentioning

confidence: 99%

“…This can give rise to disparity between the biological effects of nutrients in different foods that may have contributed to the inconsistencies in the relationships of different SFA-rich foods and CVD mortality. Clear evidence for this comes from the Multi Ethnic Study of Atherosclerosis, in which different SFA-rich foods were shown to produce differential effects on CVD risk (13) . In 5209 subjects after a 10-year period (from 2000 to …”

Section: Saturated Fat From Milk and Cvdmentioning

confidence: 99%

New perspectives on dairy and cardiovascular health

Lovegrove

Hobbs

2016

Proc. Nutr. Soc.

View full text Add to dashboard Cite

CVD are the leading cause of mortality and morbidity worldwide. One of the key dietary recommendations for CVD prevention is reduction of saturated fat intake. Yet, despite milk and dairy foods contributing on average 27 % of saturated fat intake in the UK diet, evidence from prospective cohort studies does not support a detrimental effect of milk and dairy foods on risk of CVD. The present paper provides a brief overview of the role of milk and dairy products in the diets of UK adults, and will summarise the evidence in relation to the effects of milk and dairy consumption on CVD risk factors and mortality. The majority of prospective studies and meta-analyses examining the relationship between milk and dairy product consumption and risk of CVD show that milk and dairy products, excluding butter, are not associated with detrimental effects on CVD mortality or risk biomarkers that include serum LDL-cholesterol. In addition, there is increasing evidence that milk and dairy products are associated with lower blood pressure and arterial stiffness. These apparent benefits of milk and dairy foods have been attributed to their unique nutritional composition, and suggest that the elimination of milk and dairy may not be the optimum strategy for CVD risk reduction.Milk: Dairy products: CVD: Blood pressure: Serum lipids CVD remains the leading cause of morbidity and mortality worldwide. The WHO estimated that 17·3 million people in the world died from CVD in 2008, including 7·3 million from CHD, and 6·2 million from strokes (1) . There are a number of modifiable risk factors for CVD, such as high levels of serum LDL-cholesterol (LDL-C), hypertension, diabetes, overweight/obesity, smoking, low physical activity and diet. Indeed, diets that are rich in SFA and trans fatty acids (TFA) are associated with an increased risk of CVD, and it is largely agreed that this is due, in the most part, to increased serum LDL-C (2) . Furthermore, evidence from pharmacological studies show that lowering LDL-C by an average of 1·8 mmol/l (by use of statins) reduces risk of IHD and stroke by 60 and 17 %, respectively (3) . Despite this, the relationship between SFA and CVD risk remains controversial (4) . The UK dietary guidelines recommend <10 % of total energy intake from SFA, but according to the most recent National Diet and Nutrition Survey consumption of SFA is above these recommendations, at 11·9 % of total energy intake (5) . Milk and dairy products contribute about 27 % of SFA intake in the UK diet (5) . However, evidence from a number of prospective cohort studies show that consumption of milk and other dairy products (excluding butter) are not consistently associated with an increased risk of CVD. Milk is a unique and complex food that is nutritionally complete for the sustenance of young mammals. Milk consumption in most mammals ceases soon after weaning, this coincides with down-regulation of the gene *Corresponding author: Professor J. A. Lovegrove, fax +44 (0)118 931 0080, email j.a.lovegrove@reading.ac.uk Abbreviations: BP, ...

show abstract

Dietary intake of saturated fat by food source and incident cardiovascular disease: the Multi-Ethnic Study of Atherosclerosis

Abstract: Associations of SF with health may depend on food-specific fatty acids or other nutrient constituents in foods that contain SF, in addition to SF.

Cited by 300 publications

References 42 publications

Ingesta de bebidas azucaradas analcohólicas e índice de masa corporal en escolares chilenos

Ingesta de bebidas azucaradas analcohólicas e índice de masa corporal en escolares chilenos

Effect of ewe’s (semi-skimmed and whole) and cow’s milk yogurt consumption on the lipid profile of control subjects: a crossover study

New perspectives on dairy and cardiovascular health

Contact Info

Product

Resources

About