Dietary intake and micronutrient status of adolescents: effect of vitamin and trace element supplementation on indices of status and performance in tests of verbal and non-verbal intelligence

Southon, Susan; Wright, Anthony J; Finglas, Paul; Bailey, Angela L.; Loughridge, Julie M.; Walker, Alexander D.

doi:10.1079/bjn19940195

Cited by 43 publications

(44 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This is still largely true of the latest edition of the food tables (Holland et al, 1991) since only a portion of the data has been produced by more modern HPLC methods. Using directly analysed vitamin B 6 intakes no correlation was found between intake and plasma PLP values in female adolescents, but there was a signi®cant correlation for boys (r 0.56, P`0.05; Southon et al, 1994, Bailey et al, 1997. Schuster et al (1984) found a positive correlation between PLP and vitamin B 6 intake from the previous day.…”

Section: Plasma Plp Concentrations In Human Population Groupsmentioning

confidence: 90%

High performance liquid chromatography method for the determination of pyridoxal-5-phosphate in human plasma: How appropriate are cut-off values for vitamin B6 deficiency?

1999

View full text Add to dashboard Cite

Objectives: Application of a HPLC (high performance liquid chromatography) method, using cyanide derivatisation, to the determination of plasma pyridoxal-5-phosphate (PLP) concentrations as an indicator of vitamin B 6 adequacy. Setting: The study was performed at the Institute of Food Research, Norwich, UK. Blood samples were taken at the Institute, at Health Centres, or in the volunteer's home. Subjects: 51 adolescent, 131 adult, 68 non-institutionalized elderly and 44 aged ( b 73 y) volunteers were recruited from local authority schools, local Health Centres and General Practitioners. Results: The mean PLP recovery was 92.8%. The intra-and inter-assay coef®cients of variation were 2.8% and 5.2% respectively. Mean PLP concentrations for males and females, respectively, were: adolescents (13 ± 14 y), 36.4 and 43.5 nM; adults (20 ± 64 y), 39.2 and 40.0 nM; elderly (68 ± 73 y), 34.8 and 35.3 nM; aged ( b 73 y), 57.8 and 49.0 nM. Percentages of subjects with PLP concentrations`34.4 nM were over 26% in all population groups. Mean vitamin B 6 intakes (mgag protein intake), as assessed by weighed dietary records, were all above reference nutrient intakes (15 mgag protein). Conclusions: An HPLC method, using cyanide derivitisation, has been applied to the determination of plasma PLP. Comparisons of results for local population groups with current cut-off values for plasma PLP, show large numbers of volunteers at risk of vitamin B 6 de®ciency although this is not re¯ected by vitamin B 6 intakes calculated from food tables. The 34.4 nM cut-off value for value for plasma PLP, indicating de®ciency, is questioned.

show abstract

Section: Plasma Plp Concentrations In Human Population Groupsmentioning

confidence: 90%

High performance liquid chromatography method for the determination of pyridoxal-5-phosphate in human plasma: How appropriate are cut-off values for vitamin B6 deficiency?

1999

View full text Add to dashboard Cite

show abstract

“…Published intervention studies have mainly investigated the effect of nutrient supplements and the presence/absence and content of the breakfast meal on a range of subjective and objective learning outcomes (Dickie and Bender, 1982;Meyers et al, 1989;Southon et al, 1994;Wolraich et al, 1994;Rampersaud et al, 2005;Dalton et al, 2009;Micha et al, 2010). Few studies have addressed the relationship between school lunch consumption and educational outcomes (Gietzen and Vermeersch, 1980;Kim et al, 2003;Florence et al, 2008;Selvik Ask et al, 2010) and no study has focussed on classroom behaviour in the post-lunchtime period.…”

Section: Introductionmentioning

confidence: 99%

A randomized controlled trial of the effect of school food and dining room modifications on classroom behaviour in secondary school children

Storey¹,

Pearce²,

Ashfield‐Watt³

et al. 2010

Eur J Clin Nutr

View full text Add to dashboard Cite

Background/Objectives: Adequate nutrition is considered important for learning, but there is little robust research on the association between diet and learning in school-aged children in industrialized countries. This study investigated the effect of tailored modifications to the food and dining experience in secondary schools on learning-related behaviours. Subjects/Methods: In 2008, 12 co-educational secondary schools in England were recruited. Schools were randomly allocated to receive a tailored action plan and support to modify their food provision and dining environment over a 15-week period (intervention or to control). Learning-related behaviours were systematically observed during post-lunchtime classes at all schools. Observations were made by trained observers using a validated protocol to determine whether pupils were 'on-task' (concentrating and alert) or 'off-task' (disruptive or disengaged). Results: In total, 156 pupils were observed (control n ¼ 58, intervention n ¼ 98) at baseline (12 210 and 20 560 observations, control and intervention, respectively) and at follow-up (16 846 and 23 462, respectively). On-task and off-task behaviours were similar across treatment groups at baseline. At follow-up, intervention group pupils were 18% more likely to be on-task (odds ratio (OR) 1.18, 95% confidence interval ((95% CI) 1.05-1.33) and 14% less likely to be off-task (OR 0.86, 95% CI 0.75-0.98) compared with control group pupils. Conclusions: This study suggests that modifying food provision and the dining environment can improve learning-related behaviours of secondary school pupils in the post-lunch period. This finding supports ongoing investment and interventions by local authorities across the United Kingdom to improve school food and lunchtime dining facilities.

show abstract

“…[1][2][3][4] The B group vitamins are very important water-soluble vitamins that play vital roles in metabolism, and their absences are associated with serious diseases. 5,6 The human diet sometimes does not meet the daily requirements of vitamins necessary to maintain body functions and normal development.…”

Section: Introductionmentioning

confidence: 99%

Simultaneous Determination of B Group Vitamins in Supplemented Food Products by High Performance Liquid Chromatography-Diode Array Detection

Suh¹,

Yang²,

Lee³

et al. 2011

Bulletin of the Korean Chemical Society

View full text Add to dashboard Cite

A simple HPLC-DAD method was developed and validated to determine B group vitamin content (thiamine, riboflavin, nicotinamide, pantothenic acid, pyridoxine and folic acid) in supplemented food samples, i.e., infant formula, cereal, low-calorie food, a multi-vitamin pill and a vitamin drink. In this study, the most significant advantages were simultaneous determination of the six B group vitamins in various food matrices and a small number of sample treatment steps that required only an organic solvent, acetonitrile. Moreover, this method prevents reduction of column durability, because the mobile phase does not contain ion-pairing reagents. Analytes were separated on a Develosil RPAQUEOUS C 30 (4.6 mm × 250 mm, 5 µm particle size) column with a gradient elution of acetonitrile and 20 mM phosphate buffer (pH 3.0) at a flow rate between 0.8 and 1.0 mL/min. Detection was performed at 275 nm, except for that of pantothenic acid (205 nm). The calibration curves for all six vitamins showed good linearity with correlation coefficients (r 2 ) higher than 0.995. The developed method was validated with respect to linearity, intra-and inter-day accuracy and precision, limit of quantification (LOQ), recovery and stability. The method showed good precision and accuracy, with intra-and inter-assay coefficients of variation less than 15% at all concentrations. The recovery was carried out according to the standard addition procedure, with yields ranging from 89.8 to 104.4%. This method was successfully applied to the determination of vitamin B groups in supplemented food products.

show abstract

Dietary intake and micronutrient status of adolescents: effect of vitamin and trace element supplementation on indices of status and performance in tests of verbal and non-verbal intelligence

Cited by 43 publications

References 33 publications

High performance liquid chromatography method for the determination of pyridoxal-5-phosphate in human plasma: How appropriate are cut-off values for vitamin B6 deficiency?

High performance liquid chromatography method for the determination of pyridoxal-5-phosphate in human plasma: How appropriate are cut-off values for vitamin B6 deficiency?

A randomized controlled trial of the effect of school food and dining room modifications on classroom behaviour in secondary school children

Simultaneous Determination of B Group Vitamins in Supplemented Food Products by High Performance Liquid Chromatography-Diode Array Detection

Contact Info

Product

Resources

About