Dietary fluoride prevents phosphorus-induced nephrocalcinosis in female rats

Grooten, H. N. A.; Ritskes-Hoitinga, J.; Mathot, J. N. J. J.; Lemmens, A. G.; Beynen, A.C.

doi:10.1007/bf03032692

Cited by 13 publications

(4 citation statements)

References 11 publications

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“…The powdered, pre-experimental diet consisted of the following (g/kg diet) : casein 175.3, soya-bean oil 30, coconut fat 87.2, cholesterol 9.96, cellulose 30, glucose 614.79,CaCO,12.45,NaH2PO,.2H,O 8.93, MgCO, 1.37, KCI 1.0, KHCO, 7.0, mineral premix 10, vitamin premix 12. The composition of the mineral and vitamin premix has been described (Grooten et al 1991). After another week, on day 0 of the experiment, the rats were divided into eight groups of twelve animals each on the basis of plasma cholesterol concentration and body weight.…”

Section: Animals and Experimental Proceduresmentioning

confidence: 99%

“…t Constant components consisted of the following (g/kg feed): cellulose 30, KCI 1.0, KHCO, 7.0, mineral premix 10, vitamin premix 12. The composition of the mineral and vitamin premix has been described (Grooten et al 1991). Cholesterol and triacylglycerols in plasma were measured enzymically using kits (Monotest and Test-Combination) supplied by Boehringer Mannheim GmbH, Mannheim, Germany.…”

Section: Animals and Experimental Proceduresmentioning

confidence: 99%

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Lowering effect of dietary milk-whey proteinv. casein on plasma and liver cholesterol concentrations in rats

Zhang

Beynen

1993

Br J Nutr

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The effect of dietary whey protein v. casein on plasma and Liver cholesterol concentrations was investigated in female, weanling rats. Balanced, purified diets containing either whey protein or casein, or the amino acid mixtures simulating these proteins, were used. The high-cholesterol diets (10 g cholesterol/kg feed) had either 150 or 300 g protein or amino acids/kg feed. The diets were fed for 3 weeks. At the low dietary protein level, whey protein v. casein did not affect plasma total cholesterol, but lowered the concentration of liver cholesterol. At the high dietary protein level, whey protein significantly lowered plasma and liver cholesterol and also plasma triacylglycerols. The hypocholesterolaemic effect of whey protein was associated with a decrease in very-low-density-lipoprotein cholesterol. At the high dietary protein concentration, whey protein reduced the faecal excretion of bile acids when compared with casein. The effects of intact whey protein v. casein were not reproduced by the amino acid mixtures simulating these proteins. It is suggested tentatively that the cholesterol-lowering effect of whey protein in rats is caused by inhibition of hepatic cholesterol synthesis.

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Section: Animals and Experimental Proceduresmentioning

confidence: 99%

Section: Animals and Experimental Proceduresmentioning

confidence: 99%

Lowering effect of dietary milk-whey proteinv. casein on plasma and liver cholesterol concentrations in rats

Zhang

Beynen

1993

Br J Nutr

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“…The cholesterol-free diet consisted of (g/kg): soy isolate, 180; methionine, 1.5; soybean oil, 20; coconut fat, 90; glucose, 605.4; cellulose, 30; calcium carbonate, 12.4; sodium dihydrogen phosphate, 25.2; sodium carbonate, 3.4; magnesium carbonate, 1.4, potassium hydrogen carbonate, 7.7, potassium chloride, 1 .O; mineral premix, 10; and vitamin premix; 12. The composition of the mineral and vitamin premixes has been described elsewhere [6]. Cholesterol was added at the expense of the glucose component.…”

Section: Methodsmentioning

confidence: 99%

Dietary cholesterol lowers the activity of plasma butyrylcholinesterase in rats

Lith

Beynen

1992

Nahrung

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“…H,O 33 nig,I and Zn-free mineral premix 10, vitamin premix 12. The composition of the mineral and vitamin premix has been reported elsewhere (Grooten et al 1991). After the pre-experimental period (day 0 of the experiment), the rats were divided into four groups of twelve rats each and one group of six rats.…”

Section: Diets Andfeedingmentioning

confidence: 99%

Thyroid function in rats with iodine deficiency is not further impaired by concurrent, marginal zinc deficiency

Smit

Heide

Tintelen³

et al. 1993

Br J Nutr

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The hypothesis tested was that Zn deficiency aggravates impaired thyroid function as induced by I deficiency. In two separate experiments male rats were fed on diets either deficient in Zn or in I, or deficient in both. An identical, restricted amount of food was given to each rat so that body-weight gain of the experimental groups was comparable. Zn deficiency was evidenced by reduced tibia1 Zn concentrations. I deficiency was evidenced by goitre, reduced urinary I excretion, reduced plasma thyroxine concentrations and reduced absolute amounts and concentrations of thyroxine in the thyroid. Zn deficiency had no effect on the raised thyroid weight as induced by I deficiency. Zn restriction from 184 pmol Zn/kg diet to 31 p n o l Zn/kg diet, but not to 92 pmol Zn/kg diet, significantly lowered plasma thyroxine concentration. There were no interrelated effects of Zn and I deficiencies on thyroid hormone levels. These results indicate that marginal Zn deficiency does not influence thyroid hormone metabolism in 1 deficiency.

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Dietary fluoride prevents phosphorus-induced nephrocalcinosis in female rats

Cited by 13 publications

References 11 publications

Lowering effect of dietary milk-whey proteinv. casein on plasma and liver cholesterol concentrations in rats

Lowering effect of dietary milk-whey proteinv. casein on plasma and liver cholesterol concentrations in rats

Dietary cholesterol lowers the activity of plasma butyrylcholinesterase in rats

Thyroid function in rats with iodine deficiency is not further impaired by concurrent, marginal zinc deficiency

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