Dietary Fibre and the Risk of Colorectal Cancer: a Case-Control Study

Abstract

Background: Colorectal cancer is one of the most commonly occurring cancers in China. Dietary fibre has been thought to decrease the risk of colorectal cancer in Western countries. However, studies investigating the association between dietary fibre (particularly soluble and insoluble fibres) and colorectal cancer have hitherto been lacking in China. Objective: This case-control study examined the effect of dietary fibre intake on the risk of colorectal cancer, stratified by tumour site. Materials and Methods: The study included 265 cases (colon cancer, 105; rectal cancer, 144; colon and rectal cancer, 16) and 252 controls residing in Qingdao. A food frequency questionnaire that included 121 food items was used to collect dietary information. Odds ratio (OR) and 95% confidence intervals (CI) were calculated using unconditional logistic regression analysis. Results: For food groups, controls in the study consumed more vegetables, soy food and total fibre than did colorectal cancer patients (p<0.05). The intakes of fruit, meat and sea-food did not differ significantly between cases and controls. However, we did not find any association between soy food intake and colon cancer. We observed inverse associations between total fibre intake and colorectal, colon and rectal cancer (

Dietary Patterns and Empirical Dietary Inflammatory Index in Southern Brazil and Risk of Colorectal Cancer: A Case-Control Study

“…In our investigation, the consumption of bread and white rice was associated with increased risk for intestinal carcinogenesis. In the other hand, the consumption of bread and brown rice had a protective effect, in agreement with other related epidemiological studies [8] [56].…”

Pengaruh Konsumsi Serat Dengan Pengurangan Risiko Kanker Kolon Di Negara Barat: Studi Meta Analisis

“…Beberapa penelitian sebelumnya telah menunjukkan bahwa serat makanan dikaitkan dengan pengurangan risiko kanker kolorektal. (8)(9)(10) Tetapi hasil lainnya tidak menemukan efek serat dalam penurunan risiko kanker kolorektal. (11,12) Beberapa hasil penelitian ini menggambarkan tidak selalu konsistennya hasil yang didapatkan mengenai pengaruh serat terhadap kanker kolorektal.…”

“…Asupan serat yang tinggi, terutama dari sereal atau biji-bijian dan buah-buahan, dikaitkan dengan penurunan risiko insiden kanker kolorektal. (8,12,20) Studi prospektif dalam uji skrining berbasis populasi menunjukkan bahwa individu yang mengonsumsi asupan serat makanan tertinggi telah mengurangi risiko insiden kanker kolorektal. (11) Sumber serat dari buah, sayuran, kacang-kacangan, sereal dan biji-bijian.…”

Chinese consensus on the prevention of colorectal cancer (2016, Shanghai)

“…A case‐control study in China consisting of 265 CRC patients and 252 controls showed that the amount of red meat and processed poultry meat intake was not significantly correlated with the development of CRC. Shao et al summarized the case‐control studies on risk factors for CRC in China and a meta‐analysis of the data from 6646 CRC patients and 9957 controls showed that red meat consumption was a risk factor for CRC (OR 1.62, 95% CI 1.27–2.07).…”