Dietary fiber intake in relation to coronary heart disease and all-cause mortality over 40 y: the Zutphen Study

Abstract

Background:Little is known about the effects of dietary fiber intake on long-term mortality. Objective: We aimed to study recent and long-term dietary fiber intake in relation to coronary heart disease and all-cause mortality. Design: The effects of recent and long-term dietary fiber intakes on mortality were investigated in the Zutphen Study, a cohort of 1373 men born between 1900 and 1920 and examined repeatedly between 1960 and 2000. During that period, 1130 men died, 348 as a result of coronary heart disease. Hazard ratios were obtained from timedependent Cox regression models. Results: Every additional 10 g of recent dietary fiber intake per day reduced coronary heart disease mortality by 17% (95% CI: 2%, 30%) and all-cause mortality by 9% (0%, 18%). The strength of the association between long-term dietary fiber intake and all-cause mortality decreased from age 50 y (hazard ratio: 0.71; 95% CI: 0.55, 0.93) until age 80 y (0.99; 0.87, 1.12). We observed no clear associations for different types of dietary fiber. Conclusions: A higher recent dietary fiber intake was associated with a lower risk of both coronary heart disease and all-cause mortality. For long-term intake, the strength of the association between dietary fiber and all-cause mortality decreased with increasing age.

Dietary fibre and cardiovascular disease mortality in the UK Women’s Cohort Study

“…A number of observational studies have examined the relationship between dietary fibre and risk of myocardial infarction, stroke or CVD [18][19][20], with some additionally studying different types or sources of fibre [17,21].…”

Effects of Dietary Fiber Intake on Cardiovascular Risk Factors

“…Recently, Streppel et al (2008) also observed that CHD mortality and all-cause mortality were reduced by 17% and 9%, respectively for every additional 10 g of DF per day, with no clear associations for different types of DF.…”

Macronutrients and type 1 diabetes (revision number 6)

“…Eleven cohort studies were identified that presented evidence on dietary fibre intake and coronary events (Fehily et al, 1993;Knekt et al, 1994;Pietinen et al, 1996;Rimm et al, 1996;Todd et al, 1999;Appleby et al, 1999;Wolk et al, 1999;Liu et al, 2002;Bazzano et al, 2003;Mozaffarian et al, 2003;Streppel et al, 2008), eight of which were included in a meta-analysis. Three cohort studies, that could not be included in the metaanalysis as they did not report the necessary data, indicated no significant association between dietary fibre and coronary events (Fehily et al, 1993;Knekt et al, 1994;Todd et al, 1999).…”

“…Six cohort studies were identified that presented evidence on vegetable fibre intake and coronary events, all of which were included in a meta-analysis (Pietinen et al, 1996;Rimm et al, 1996;Wolk et al, 1999;Liu et al, 2002;Mozaffarian et al, 2003;Streppel et al, 2008). One cohort study was subsequently identified in the update search (Eshak et al, 2010) (Cardio-metabolic review, cardiovascular disease chapter p 78-81, 84; Update search table 24).…”

“…Eight cohort studies were identified that presented evidence on cereal fibre intake and coronary events (Fehily et al, 1993;Pietinen et al, 1996;Rimm et al, 1996;Wolk et al, 1999;Liu et al, 2002;Mozaffarian et al, 2003;Streppel et al, 2008;Kaushik et al, 2009), six of which were included in a meta-analysis. Two cohort studies could not be included in a meta-analysis as they did not report the necessary data.…”