Dietary fatty acids alter mitochondrial phospholipid fatty acyl composition and proton leak in <i>Drosophila melanogaster</i>

Abstract

Two groups of fruit flies (Drosophila melanogaster) were maintained on different diets.Mitochondria were isolated, proton leak was measured and phospholipid fatty acid composition determined. Mitochondria from flies fed on corn-base meal (containing high amounts of polyunsaturated fatty acids, 18:2(n-6) and 18:3(n-3) and low amounts of monounsaturated fatty acid, 18:1(n-9)) contained more polyunsaturated fatty acids in their membranes than mitochondria from flies fed on yeast-base meal (containing less amount of polyunsaturates and high amount of monounsaturates). The more polyunsaturated mitochondria were leakier to protons than the more monounsaturated mitochondria.

Foraging at wastewater treatment works affects brown adipose tissue fatty acid profiles in banana bats

“…BrAT phospholipids can also be selectively mobilised to provide much-needed fatty acids to other tissues, such as highly oxidative muscles ( Groscolas and Herzberg, 1997 ). EFAs, such as PUFAs, are important in maintaining torpor by allowing minimum body temperature to decrease without the risk of death, and maintaining basal metabolic rates during periods of inactivity ( Chalvardjian, 1964 ; Ocloo, 2006 ). In fact, an optimal n-6 to n-3 PUFA ratio in tissues is even more important than merely high EFA concentrations ( Ruf and Arnold, 2008 ).…”