Dietary exposure assessment of infant formula and baby foods’ oxidized lipids in the US population

Maldonado‐Pereira, Lisaura; Barnaba, Carlo; Medina-Meza, Ilce Gabriela

doi:10.1016/j.fct.2022.113552

Cited by 3 publications

(1 citation statement)

References 53 publications

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“…Our lab has led a few efforts to identify DOxS biomarkers in food items, including baby foods 14 and UPFs, 29 as well as performed dietary exposure modeling in selective populations using existing food consumption databases. 50 However, these efforts require further support to deepen our understanding of DOxS metabolism in humans, which remains incomplete.…”

Section: Papermentioning

confidence: 99%

FooDOxS: a database of oxidized sterols content in foods

Medina-Meza,

Vaidya,

Barnaba

2024

Food Funct.

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Section: Papermentioning

confidence: 99%

FooDOxS: a database of oxidized sterols content in foods

Medina-Meza,

Vaidya,

Barnaba

2024

Food Funct.

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Oxidative Status of the Ultra-Processed Foods in the Western Diet

Maldonado‐Pereira

Barnaba

Medina-Meza

2023

Preprint

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Ultra-processed foods (UPFs) and their nutritional value have become a trending topic in the scientific community because of their increasing demand, and their potentially adverse effects on human health. Besides the poor nutritional value attributed to UPFs, countless studies have also reported the presence of different dietary oxidized substances in these meals. DOxS are associated with several chronic diseases such as cardiometabolic diseases (CMD), cancer, diabetes, Parkinson's, and Alzheimer's disease. In this study, a database of DOxS and other dietary metabolites detected in 63 UPFs meals part of the Western diet is reported. Significant differences were found in DOxS and phytosterol contents between ready-to-eat and fast food (FF). Putative biomarkers were suggested for RTE (brassicasterol) and FF (7a-OH and 7b-OH), as well as for all 6 different food categories: dairy (brassicasterol), eggs & derivatives (stigmasterol and b-sitosterol), meat & poultry (7a-OH), seafood, baby food (b-sitosterol), and others (campesterol). Ideally, the use of dietary biomarkers could potentially help in the future to identify in an early stage the presence of different chronic diseases, and even, prevent their development. Nevertheless, an exposure assessment is critical to understand the exposure level of DOxS and their relationship with different chronic diseases.

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Oxidative Status of Ultra-Processed Foods in the Western Diet

Maldonado-Pereira,

Barnaba,

Medina-Meza

2023

Nutrients

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Ultra-processed foods (UPFs) have gained substantial attention in the scientific community due to their surging consumption and potential health repercussions. In addition to their well-established poor nutritional profile, UPFs have been implicated in containing various dietary oxidized sterols (DOxSs). These DOxSs are associated with a spectrum of chronic diseases, including cardiometabolic conditions, cancer, diabetes, Parkinson’s, and Alzheimer’s disease. In this study, we present a comprehensive database documenting the presence of DOxSs and other dietary metabolites in >60 UPFs commonly consumed as part of the Western diet. Significant differences were found in DOxS and phytosterol content between ready-to-eat (RTE) and fast foods (FFs). Biomarker analysis revealed that DOxS accumulation, particularly 25-OH and triol, can potentially discriminate between RTEs and FFs. This work underscores the potential utility of dietary biomarkers in early disease detection and prevention. However, an essential next step is conducting exposure assessments to better comprehend the levels of DOxS exposure and their association with chronic diseases.

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Dietary exposure assessment of infant formula and baby foods’ oxidized lipids in the US population

Cited by 3 publications

References 53 publications

FooDOxS: a database of oxidized sterols content in foods

FooDOxS: a database of oxidized sterols content in foods

Oxidative Status of the Ultra-Processed Foods in the Western Diet

Oxidative Status of Ultra-Processed Foods in the Western Diet

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