Dietary Dried Sweetspire (&lt;i&gt;Itea&lt;/i&gt;) Powder Reduces Body Fat Accumulation in Rats Fed with a High-fat Diet

Higaki, Shunsuke; Inai, Reiko; Mochizuki, Susumu; Yoshihara, Akihide; Matsuo, Tatsuhiro

doi:10.5650/jos.ess22111

Cited by 5 publications

(2 citation statements)

References 19 publications

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“…This suggests that longterm WBV may be a safe and promising approach for preventing and treating obesity, particularly under conditions that promote obesity. Further research is needed to understand the mechanisms and determine optimal WBV protocols for maximum benefits [72].…”

Section: Effects Of Low Frequency Whole-body Vibrations On Ratsmentioning

confidence: 99%

Investigation of vehicle-induced whole-body vibration with experimental rat models

Nur HAZAR YAVUZ,

YAVUZ

2023

jrp

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This comprehensive study delves into the profound impact of low frequency whole-body vibrations (WBV) on health, focusing on the utilization of rat models for understanding this complex phenomenon. It highlights the adverse effects of low frequency vehicle vibrations on human health, encompassing musculoskeletal discomfort, fatigue, concentration deficits, potential gastrointestinal issues, hearing impairment, and psychological stress. WBV's influence extends to physiological and cognitive consequences, affecting multiple systems. Prolonged WBV exposure, particularly in the lumbar region, is associated with spinal disorders. To navigate ethical challenges in studying WBV in humans, rat models are crucial tools. These models, with customized parameters, offer insights into various health aspects, including bone density, muscle strength, hormonal responses, cardiovascular parameters, and more. Advantages and disadvantages of using low-frequency vibrations in rat models are discussed. While demonstrating WBV's potential effect in research, further exploration is essential to optimize parameters and applications, always prioritizing ethical considerations and regulations. The article concludes by proposing measures to mitigate vehicle vibration impacts on drivers, emphasizing the collaboration of manufacturers, drivers, and regulators for safer and healthier driving experiences.

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Section: Effects Of Low Frequency Whole-body Vibrations On Ratsmentioning

confidence: 99%

Investigation of vehicle-induced whole-body vibration with experimental rat models

Nur HAZAR YAVUZ,

YAVUZ

2023

jrp

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“…In addition, allitol occurs naturally in Itea, a deciduous shrub belonging to the Saxifrageaceae family, along with D-allulose (Hough & Stacey, 1966). Our previous study revealed that the long-term feeding of rats with a dietary supplement of dried Itea powder suppresses body fat accumulation, even though contains very small amounts of rare sugars , 2022c. We hypothesized that this effect is due to the simultaneous intake of D-allulose and allitol in Itea.…”

Section: Introductionmentioning

confidence: 98%

Effect of simultaneous intake of rare sugars allitol and D-allulose on intra-abdominal fat accumulation in rats

Matsuo,

Higaki,

Inai

et al. 2023

jftr

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Allitol, one of the sugar alcohols, is a rare sugar produced by reducing d-allulose contained in Itea, a deciduous shrub belonging to the Saxifrageaceae family. We previously found that the long-term feeding of rats with a diet supplemented with Itea powder suppressed obesity. The present study aimed to further investigate whether this effect on body fat accumulation may be attributed to the simultaneous intake of allitol and d-allulose in Itea. Thirty-two male 3-week-old Wistar rats were randomly divided into four groups of eight. The rats had ad libitum access to the control (C), 3% allitol (A), 3% d-allulose (P), or 3% allitol + 3% d-allulose (AP) diet for 8 weeks, after which the rats were euthanized. d-Allulose significantly lowered the final body weight, weight gain, and quantities of perirenal, mesenteric, and total abdominal adipose tissue. Allitol significantly decreased the mesenteric adipose tissue weight. However, we found no combined effect between d-allulose and allitol on all abdominal fat. The liver glucose-6-phosphate dehydrogenase activity was significantly higher in the d-allulose-supplemented groups. Cecal weight, surface area, and content weight were found to be significantly higher in Groups A and AP than those in Groups C and P, suggesting a higher intestinal fermentability of allitol. Our results suggest that allitol and d-allulose have anti-obesity properties that are affected through different mechanisms but are non-synergistic.

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Impact of artificial sweeteners and rare sugars on the gut microbiome

Lee,

So,

Yoo

et al. 2024

Food Sci Biotechnol

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Dietary Dried Sweetspire (<i>Itea</i>) Powder Reduces Body Fat Accumulation in Rats Fed with a High-fat Diet

Cited by 5 publications

References 19 publications

Investigation of vehicle-induced whole-body vibration with experimental rat models

Investigation of vehicle-induced whole-body vibration with experimental rat models

Effect of simultaneous intake of rare sugars allitol and D-allulose on intra-abdominal fat accumulation in rats

Impact of artificial sweeteners and rare sugars on the gut microbiome

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