Dietary Control and Etiology of Dental Caries

SCHOENTHAL, LUDWIG

doi:10.1001/archpedi.1933.01960010101010

Cited by 7 publications

(9 citation statements)

References 20 publications

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“…Fifty‐three references were evaluated in detail, 24 of which were excluded because of the absence of incident caries outcome statistics, the lack of assignment to vitamin D by the investigator for the purpose of caries control, or the lack of controls . Twenty‐nine references remained, which included articles, abstracts, and excerpts of grant reports . In one reference that reported on three CCTs, one CCT without reported follow‐up time was eliminated.…”

Section: Resultsmentioning

confidence: 99%

“…Thirteen of the 24 CCTs assigned patients to treatments (Table ). Five of these 13 CCTs assigned patients to vitamin D on the basis of health awareness or caries experience . Eleven of the 24 CCTs assigned clusters of patient to treatment, with the clusters being institutions ( n = 2), cottages ( n = 6), classrooms ( n = 1), schools ( n = 1), or unspecified groupings ( n = 1) None of the 11 cluster CCTs reported assigning vitamin D on the basis of health awareness or caries experience.…”

Section: Resultsmentioning

confidence: 99%

“…Comparability in baseline caries score between intervention and control groups could be evaluated for 23 of 38 treatment comparisons, and significant baseline inequality in caries experience was present for 4 vitamin D estimates (Appendix S3) . The quality score ranged from 6 to 21, with a mean of 14.8 (standard deviation, 4.0).…”

Section: Resultsmentioning

confidence: 99%

“… The “–” indicates that no information was provided about whether caries was diagnosed on primary or permanent dentition …”

Section: Methodsmentioning

confidence: 99%

“… Significant baseline inequality may have been due to a typographical error in Table , p. 96 of the Schoenthal publication.…”

Section: Methodsmentioning

confidence: 99%

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Vitamin D and dental caries in controlled clinical trials: systematic review and meta-analysis

2012

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Vitamin D has been used to prevent and treat dental caries. The objective of this study was to conduct a systematic review of controlled clinical trials (CCTs) assessing the impact of vitamin D on dental caries prevention. Random-effects and meta-regression models were used to evaluate overall and subgroup-specific relative-rate estimates. Twenty-four CCTs encompassing 2,827 children met the inclusion criteria. Twenty-two of the 24 CCTs predated modern clinical trial design, some of which nonetheless reported characteristics such as pseudo-randomization (n = 2), blinding (n = 4), or use of placebos (n = 8). The relative-rate estimates of the 24 CCTs exhibited significant heterogeneity (P < 0.0001), and there was evidence of significant publication bias (P < 0.001). The pooled relative-rate estimate of supplemental vitamin D was 0.53 (95% CI, 0.43-0.65). No robust differences were identified between the caries-preventive effects of vitamin D(2) , vitamin D(3) , and ultraviolet radiation (Prob > F = 0.22). The analysis of CCT data identified vitamin D as a promising caries-preventive agent, leading to a low-certainty conclusion that vitamin D may reduce the incidence of caries.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

“… The “–” indicates that no information was provided about whether caries was diagnosed on primary or permanent dentition …”

Section: Methodsmentioning

confidence: 99%

“… Significant baseline inequality may have been due to a typographical error in Table , p. 96 of the Schoenthal publication.…”

Section: Methodsmentioning

confidence: 99%

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Vitamin D and dental caries in controlled clinical trials: systematic review and meta-analysis

2012

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Concentration of Calcium and Phosphorus in the Serum of Children

SCHOENTHAL¹

1933

Arch Pediatr Adolesc Med

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Data on calcium and phosphorus 1 of the serums of 250 healthy children from 5 to 16 years of age were analyzed in an investigation of dental caries.2 This gave us an opportunity of studying the physiologic relation of these substances to such factors as age, sex and development and their physiologic variation. METHODSAfter the children had rested for at least fifteen minutes, blood was withdrawn with as little stasis as possible. It was not collected under oil. As soon as the blood clotted, the specimens were centrifugated, and the serum was separated from them. All determinations were made immediately after the collection of the blood. Duplicates for calcium were done, except in a few cases.Calcium.\p=m-\Amodification of the Clark-Collip method,3 involving the adjustment of the ph to about 5, and two washings of the precipitate were used. The average deviation of duplicates was 0.25 mg. per hundred cubic centimeters (about 3.6 per cent).Phosphorus.\p=m-\Inthe great majority of the cases the Tisdall method4 was used. Duplicates with this method showed an average difference of 2.6 per cent. The Fiske-Subbarrow method5 was employed in 8 cases ; the average difference between duplicates was 1.9 per cent. The results obtained with the Tisdall and From the

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Effect of a Milk Supplement on the Physical Status of Institutional Children

Roberts¹

1938

Am J Dis Child

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The two preceding articles in this series 1 have shown that the daily addition of a pint (473 cc.) equivalent of evaporated milk to the diets of children in an institution (one group receiving irradiated and the other nonirradiated milk) produced a measurable increase of growth in height and weight and in ossification of the bones in the wrists as compared with that of the control group given the regular institutional diet. The present study deals with the progress of dental caries in the same groups of children during the same period. LITERATURE A number of workers have reported a striking arrest of dental caries as a result of different types of dietary supplement. Since their findings have been reviewed many times (Hanke,2 1934) they will be only briefly The expenses of this investigation were defrayed in part by the Irradiated Evaporated MilkInstitute.

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Dietary Control and Etiology of Dental Caries

Cited by 7 publications

References 20 publications

Vitamin D and dental caries in controlled clinical trials: systematic review and meta-analysis

Vitamin D and dental caries in controlled clinical trials: systematic review and meta-analysis

Concentration of Calcium and Phosphorus in the Serum of Children

Effect of a Milk Supplement on the Physical Status of Institutional Children

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