Dietary calcium intake and bone loss from the spine in healthy postmenopausal women

Dawson‐Hughes, Bess; Jacques, Paul F.; Shipp, Clanton C.

doi:10.1093/ajcn/46.4.685

Cited by 92 publications

(25 citation statements)

References 11 publications

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“…Bone mass of the heel was assessed as stiffness units (SI) from calcaneal ultrasound using a Lunar Achilles InSight Works (GE Madison, Wisconsin). Participants completed food frequency questionnaires to evaluate calcium and vitamin D intake in their diet and vitamin supplements [17].…”

Section: Discussionmentioning

confidence: 99%

The effect of moderate impact exercise on skeletal integrity in master athletes

et al. 2008

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Section: Discussionmentioning

confidence: 99%

The effect of moderate impact exercise on skeletal integrity in master athletes

et al. 2008

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“…[17][18][19] The weaker association of adolescent milk consumption with bone mineral density may reflect less variation in intake (adults have greater independence in beverage choices), inaccuracies of longer recall, or the lower per capita milk consumption during the Great Depression, which coincided with many participants' adolescent years. Alternatively, it may reflect the fact that most members of this cohort were children or teenagers when vitamin 'D, which mediates the absorption of calcium,5 was first added to the US milk supply.0…”

Section: Discussionmentioning

confidence: 99%

Lifetime milk consumption and bone mineral density in older women.

Soroko¹,

Holbrook²,

Edelstein³

et al. 1994

Am J Public Health

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This study examined the relationship between lifetime milk consumption both axial and appendicular bone mineral density in 581 postmenopausal White women. Positive significant, graded associations between milk consumption in adulthood and bone mineral density at the spine, total hip, trochanter, intertrochanter, and midradius, but not the ultradistal wrist or femoral neck, were observed. Adolescent milk consumption showed similar, statistically significant associations (spine and midradius). Associations were independent of age, body mass index, years postmenopausal, thiazide, estrogen and alcohol use, smoking, and exercise. Regular milk consumption in youth and adulthood is associated with better bone mineral density at cortical and trabecular sites in elderly women.

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“…10 Subjects found to have calcium intake below 1,200 mg a day received supplements containing calcium carbonate 500 mg with 200 Us of vitamin D per tablet (Oscal plus D; GlaxoSmithKline, Middlesex, United Kingdom).…”

Section: Methodsmentioning

confidence: 99%

Risedronate Prevents Bone Loss in Breast Cancer Survivors: A 2-Year, Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Greenspan

Brufsky

Lembersky

et al. 2008

JCO

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Purpose-Limited data are available on the efficacy of oral bisphosphonate therapy in breast cancer survivors. Our goal was to examine prevention of breast cancer-related bone loss in this cohort.Patients and Methods-Eighty-seven postmenopausal women after chemotherapy for breast cancer were randomly assigned to once-weekly risedronate 35 mg or placebo for 24 months. Outcomes included bone mineral density (BMD) and turnover markers. AUTHORS' DISCLOSURES OF POTENTIAL CONFLICTS OF INTERESTAlthough all authors completed the disclosure declaration, the following author(s) indicated a financial or other interest that is relevant to the subject matter under consideration in this article. Certain relationships marked with a "U" are those for which no compensation was received; those relationships marked with a "C" were compensated. NIH-PA Author ManuscriptNIH-PA Author Manuscript NIH-PA Author ManuscriptResults-At study initiation, 13% of patients were on an aromatase inhibitor (AI). After 24 months, there were differences of 1.6 to 2.5% (P < .05) at the spine and hip BMD between the placebo and risedronate groups. At study completion, 44% were on an AI. Adjusting for an AI, women on placebo plus AI had a decrease in BMD of (mean ± SE) 4.8% ± 0.8% at the spine and 2.8% ± 0.5% at the total hip (both P < .001). In women on risedronate + AI, the spine decreased by 2.4% ± 1.1% (P < .05) and was stable at the hip. Women in the placebo group not on an AI, maintained BMD at the spine, and had a 1.2% ± 0.5% loss at the total hip (P < .05). Women who received risedronate but no AI had the greatest improvement in BMD of 2.2% ± 0.9% (P < .05) at the total hip. Bone turnover was reduced with risedronate. There were no differences in adverse events between the groups.Conclusion-We conclude that in postmenopausal women with breast cancer with or without AI therapy, once-weekly oral risedronate was beneficial for spine and hip BMD, reduced bone turnover, and was well tolerated.

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Dietary calcium intake and bone loss from the spine in healthy postmenopausal women

Cited by 92 publications

References 11 publications

The effect of moderate impact exercise on skeletal integrity in master athletes

The effect of moderate impact exercise on skeletal integrity in master athletes

Lifetime milk consumption and bone mineral density in older women.

Risedronate Prevents Bone Loss in Breast Cancer Survivors: A 2-Year, Randomized, Double-Blind, Placebo-Controlled Clinical Trial

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