Dietary Approaches for Bone Health: Lessons from the Framingham Osteoporosis Study

Sahni, Shivani; Mangano, Kelsey M.; McLean, Robert R.; Hannan, Marian T.; Kiel, Douglas P.

doi:10.1007/s11914-015-0272-1

Cited by 88 publications

(64 citation statements)

References 121 publications

(103 reference statements)

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“…The reason for these negative patterns of association are unclear. Cream was previously reported to have a negative effect on aBMD because of its low nutrient density, but surprisingly the proposed negative associations were not observed in the current study.…”

Section: Discussioncontrasting

confidence: 84%

Higher Dairy Food Intake Is Associated With Higher Spine Quantitative Computed Tomography (QCT) Bone Measures in the Framingham Study for Men But Not Women

Dongen

Kiel

Soedamah‐Muthu

et al. 2018

Journal of Bone and Mineral Research

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Previous studies found that dairy foods were associated with higher areal bone mineral density (BMD). However, data on bone geometry or compartment-specific bone density is lacking. In this cross-sectional study, the association of milk, yogurt, cheese, cream, milk+yogurt, and milk+yogurt+cheese intakes with quantitative computed tomography (QCT) measures of bone were examined, and we determined if associations were modified by serum vitamin D (25-OH D, tertiles) or age (<50 versus ≥50 years). Participants were 1522 men and 1104 women (aged 32 to 81 years, mean 50 years [men]; 55 years [women]) from the Framingham Heart Study with measures of dairy food intake (servings/wk) from a food-frequency questionnaire, volumetric BMD (vBMD, integral and trabecular, g/cm ), cross-sectional area (CSA, cm ), and estimated vertebral compressive strength (VCS, N) and 25-OH D (radioimmunoassay). Sex-specific multivariable linear regression was used to calculate the association of dairy food intake (energy adjusted) with each QCT measure, adjusting for covariates. Mean milk intake ±SD was 6 ± 7 servings/week in both men and women. In men, higher intake of milk, milk+yogurt, and milk+yogurt+cheese was associated with higher integral (p = 0.001 to 0.006) and trabecular vBMD (p = 0.006 to 0.057) and VCS (p = 0.001 to 0.010). Further, a higher cheese intake was related with higher CSA (p = 0.049). In women, no significant results were observed for the dairy foods, except for a positive association of cream intake with CSA (p = 0.016). The associations appeared to be stronger in older men. Across 25-OH D tertiles, dairy was positively associated with bone health. In summary, men with higher intakes of milk, milk+yogurt, and milk+yogurt+cheese had higher trabecular and integral vBMD and VCS but not CSA. Dairy intake seems to be most beneficial for older men, and dairy continued to have positive associations among all 25-OH D levels. © 2018 American Society for Bone and Mineral Research.

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Section: Discussioncontrasting

confidence: 84%

Higher Dairy Food Intake Is Associated With Higher Spine Quantitative Computed Tomography (QCT) Bone Measures in the Framingham Study for Men But Not Women

Dongen

Kiel

Soedamah‐Muthu

et al. 2018

Journal of Bone and Mineral Research

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“…Studies have shown that poor dietary quality, characterized by lower intakes of fiber, fruits, vegetables, whole grains, lean protein, and a higher intake of unhealthy fats are associated higher risk for diabetes, 23 cardiovascular diseases, 24 certain types of cancer, 25 decline in physical and cognitive functions, 26,27 fall injuries, 28 hip fractures, 29 and earlier loss of independent living. 30,31 Racial differences in diet quality may contribute to health disparities in older age.…”

Section: Discussionmentioning

confidence: 99%

Racial differences in eating patterns and food purchasing behaviors among urban older women

Youssef

Procter-Gray

et al. 2017

The Journal of nutrition, health and aging

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Objectives To examine differences in diet and food purchasing behaviors between Black and White older women living in urban neighborhoods. Design Cross-sectional observational study. Setting Urban neighborhoods in Washington, DC, USA. Participants Community-dwelling White and Black women of age 65 and older. Measurements Participants were queried on diet via 24-hour recalls, food purchasing habits, their use of neighborhood resources and local travel patterns. Frequency and location of self-reported food purchasing and consumption were compared by race. Results In 2014 and 2015, 49 White and 44 Black older women were enrolled in the study. Compared to Whites, Blacks reported lower daily caloric intake (mean (SD) 1314 (404) vs. 1529 (448), p=0.02), with a higher percent of calories from protein and fat 1.8 (7.0), p=0.03), and a slightly higher polyunsaturated to saturated fat ratio (p=0.05). Blacks had substantially lower healthy eating index (HEI) (33.5 (10.2) vs. 43.9 (10.8) of 80 possible points, p<0.001), daily intake (grams) of total fiber (15.3 (8.1) vs. 22.9 (8.5), p<0.001), insoluble fiber (10.8 (6.9) vs. 15.9 (6.5), p<0.001), and soluble fiber (4.5 (2.0) vs. 6.9 (2.8), p<0.001). Blacks had lower intake of micronutrients, alcohol and caffeine. Blacks shopped for groceries less often (4.4 (3.0) vs. 6.2 (3.0) monthly; p=0.006) and spent a longer time traveling to stores (15.8 (9.1) vs. 11.5 (7.2) minutes per trip, p=0.02). A lower percent of Blacks walked to stores (14% vs. 40%, p=0.003) and a higher percent of Blacks rode in a car with someone else (33% vs. 6%, p<0.001). Conclusions In an urban setting, food consumption and purchasing behaviors differed substantially between older Black and White women, which should be further investigated and considered to promote healthy eating in older populations.

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“…Dietary contributors to osteoporosis have focused on vitamin D and calcium, but nutrients beyond these (3,4) may also affect bone health. Intake of fruits and vegetables (5) and a fruit, vegetable and cereal pattern (6) in the Framingham cohorts have been suggested to be positively related to change in hip BMD in men but not in women.…”

Section: Introductionmentioning

confidence: 99%

Association Between Dietary Fiber Intake and Bone Loss in the Framingham Offspring Study

Felson

Kiel

et al. 2017

Journal of Bone and Mineral Research

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Dietary fiber may increase calcium absorption, but its role in bone mineralization is unclear. Furthermore, the health effect of dietary fiber may be different between genders. We examined the association between dietary fiber (total fiber and fiber from cereal, fruits, vegetables, nuts and legumes) and bone loss at the femoral neck, trochanter and lumbar spine (L2–4) in older men and women. In the Framingham Offspring Study, at baseline (1996–2001), diet was assessed using the Willett food frequency questionnaire and bone mineral density (BMD) was measured using dual-energy X-ray absorptiometry. Follow-up BMD was measured in 2001–2005 and 2005–2008 among 792 men (mean age, 58.1yr; BMI, 28.6kg/m2) and 1,065 women (57.3yr; 27.2kg/m2). We used sex-specific generalized estimating equations in multivariable regressions to estimate the difference (β) of annualized BMD change in percent (%ΔBMD) at each skeletal site per 5 g/d increase in dietary fiber. We further estimated the adjusted mean for bone loss (annualized %ΔBMD) among participants in each higher quartile (Q2, Q3 or Q4) compared with those in the lowest quartile (Q1) of fiber intake. Higher dietary total fiber (β=0.06, p=0.003) and fruit fiber (β=0.04, p=0.008) was protective against bone loss at the femoral neck in men but not in women. When examined in quartiles, men in Q2–Q4 of total fiber had significantly less bone loss at the femoral neck versus those in Q1 (all p<0.04). Fiber from vegetables appeared to be protective against spine bone loss in women but not men. There were no associations with cereal fiber or nut and legume fiber and bone loss in men or women. Our findings suggest that higher dietary fiber may modestly reduce bone loss in men at the hip.

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Dietary Approaches for Bone Health: Lessons from the Framingham Osteoporosis Study

Cited by 88 publications

References 121 publications

Higher Dairy Food Intake Is Associated With Higher Spine Quantitative Computed Tomography (QCT) Bone Measures in the Framingham Study for Men But Not Women

Higher Dairy Food Intake Is Associated With Higher Spine Quantitative Computed Tomography (QCT) Bone Measures in the Framingham Study for Men But Not Women

Racial differences in eating patterns and food purchasing behaviors among urban older women

Association Between Dietary Fiber Intake and Bone Loss in the Framingham Offspring Study

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